Daily Papers

Learning long-horizon humanoid loco-manipulation poses a dual challenge: it requires not only the robust execution of meta-skills but also their seamless, closed-loop chaining equipped with autonomous recovery. Existing approaches remain limited: explicit humanoid-object interaction representations offer precision but are notoriously difficult for high-level planning, whereas implicit skill embeddings are compact but lack the interpretability required for reliable composition. We propose \ours, a hierarchical framework centered on contact flow (CF), a compact representation consisting of key body trajectories and time-series binary contact signals. Leveraging this shared interface, our low-level policy CF-Track learns a unified library of loco-manipulation skills, while our high-level module CF-Gen heuristically synthesizes future contact-flow sequences. To support this setting, we additionally collect the OmniContact dataset, a MoCap-based HOI corpus for humanoid loco-manipulation (Appendix~sec:dataset). Together, they enable robust execution, autonomous failure recovery, and flexible composition of meta-skills for long-horizon tasks. Experiments show that OmniContact achieves \(98.7\%\) success on Carry Box and \(76.5\%\) on Push-Stack Boxes, outperforming prior baselines by average margins of \(40.9\%\) in meta-skill and \(66.5\%\) in skill chaining. Besides, our framework naturally integrates with VLMs for semantic task decomposition, enabling complex, semantically grounded loco-manipulation behaviors, such as arranging scattered boxes into a heart shape.

World models offer a promising route toward robot planning by enabling agents to imagine and verify the consequences of actions before execution. However, current video-based world models often struggle to capture the physical constraints that govern manipulation, particularly contact. Further, their action conditioning is often constrained to specific embodiments such as parallel grippers. We propose Contact Flow, an embodiment-agnostic action representation that encodes manipulation through the trajectory of 3D contact points between an actor and a target object. By discarding actor-specific appearance and kinematics, Contact Flow provides a shared conditioning signal for both human demonstrations and robotic execution. Therefore, we can train a large-scale video generative model on both human and robotic object interaction videos conditioned on Contact Flow, yielding a world model that predicts physically plausible manipulation outcomes. We integrate this model into a propose-imagine-verify-act pipeline, where generated rollouts are assessed by a vision-language model before execution. Experiments on the DROID dataset and real-world tabletop manipulation tasks demonstrate that Contact Flow enables transfer between human demonstrations and different robotic embodiments.

Most learned dexterous grasp generators relegate contact forces to a downstream verification step, so a kinematically-plausible pose can still violate the conditions for a stable physical grasp. We address this with EquiDexFlow, an SE(3)-equivariant flow-matching model that jointly predicts wrist pose, joint angles, fingertip contacts, surface normals, and contact forces from an object point cloud. Our architecture projects contacts onto the object surface and forces into the Coulomb friction cone by construction, so placement and friction compliance hold without loss penalties. We prove end-to-end SE(3) equivariance and verify it empirically over 200 rotations, with wrist residuals below 0.04^circ and exactly zero joint deviation. Trained on 8,100 force-closure grasps across 81 objects for the 16-DoF Allegro Hand, our model achieves zero friction violations, the best composite score, and the lowest wrench residual among all ablation variants. We retarget decoded fingertip contacts to a 16-DoF LEAP Hand via per-finger inverse kinematics, and our hardware-feasible refinement places every joint at least 5% inside its actuator envelope while preserving wrench balance. On the physical robot, retargeted EquiDexFlow-decoded grasps complete open-loop pick-and-hold trials on all six test objects, with every asymmetric object succeeding at both the canonical pose and a 120^circ co-rotation. Videos, code, and checkpoints are available at https://equidexflow.github.io.

Tactile sensing is a crucial capability for Vision-Language-Action (VLA) architectures, as it enables dexterous and safe manipulation in contact-rich tasks. However, reliance on dedicated tactile hardware increases cost and reduces reproducibility across robotic platforms. We argue that tactile-aware manipulation can be learned offline and deployed without direct haptic feedback at inference. To this end, we present HapticVLA, which proceeds in two tightly coupled stages: Safety-Aware Reward-Weighted Flow Matching (SA-RWFM) and Tactile Distillation (TD). SA-RWFM trains a flow-matching action expert that incorporates precomputed, safety-aware tactile rewards penalizing excessive grasping force and suboptimal grasping trajectories. TD further transfers this tactile-aware capability into a conventional VLA: we distill a compact tactile token from the SA-RWFM teacher and train a student VLA to predict that token from vision and state modalities, enabling tactile-aware action generation at inference without requiring on-board tactile sensors. This design preserves contact-rich tactile-aware reasoning within VLA while removing the need for on-board tactile sensors during deployment. On real-world experiments, HapticVLA achieves a mean success rate of 86.7%, consistently outperforming baseline VLAs - including versions provided with direct tactile feedback during inference.

Capillary-driven transport offers a simple, self-sustained alternative to externally pumped microfluidic systems, yet achieving precise control of such flows remains challenging. We experimentally and theoretically investigate capillary flow in rectangular microchannels when a liquid meniscus encounters a geometric step with varying channel width and height. Depending on the contact angle and step dimensions, the meniscus either pins or advances, defining distinct flow and no-flow regimes. Introducing a lateral offset between channel sidewalls provides an additional geometric control that enables reversible switching from a pinned to a flowing state, even for liquids with relatively high contact angles. We rationalize these transitions using numerical simulations and an energy-based scaling model that captures the balance between surface tension and Laplace pressure at the step. Finally, we demonstrate synchronization of capillary fronts in parallel microchannels by combining stepped and offset geometries. These results establish a simple, geometry-mediated mechanism for passive control and synchronization of capillary flows, expanding the design space for microfluidic systems.

We address the problem of understanding when and why Vision-Language-Action models struggle with contact-rich manipulation tasks that require precise physical interaction. Prior work has primarily focused on addressing contact failures through force-augmented architectures and training-time regularizers, yet the root causes of these failures remain underexplored. We identify two distinct failure modes underlying this gap. Precision failures are rooted in a flow-matching policy training mismatch, and force failures arise from the distinctive structure of force signals. We address each failure mode with a targeted mechanism and combine them into FACT, which achieves 66% average success rate across five contact-rich tasks against 41% for the best prior baseline, in an evaluation spanning almost 2,500 real-world rollouts.

We present LYRIC, a generative flow-matching controller for language-driven physics-based contact-rich interaction control, that enables simulated characters to perform contact-rich whole-body object interactions from a free-form language instruction and a sparse terminal object goal. To obtain reliable expert trajectories from imperfect motion-capture references, a single tracking policy is trained using geometry-conditioned interaction rewards and relaxed reference tracking near hand-object contact. To guide interaction progress without prescribing a full-body kinematic reference, we factorize the controller into a task-level planner that predicts short-horizon object and humanoid-root trajectories, and an action generator that resolves whole-body motion and contacts in closed loop. After behavior cloning, we freeze the planner and post-tune the action generator on policy using the planner's predictions as stable supervision for intermediate task progression. In a controlled OMOMO evaluation, our tracker achieves 64.3% success compared with 53.2% for an InterMimic reimplementation, while a unified policy achieves 76.5% on the full OMOMO dataset. On the held-out split, LYRIC achieves 90.3% task success, compared with 74.2% for the strongest matched kinematic-planner baseline, with better semantic alignment and motion quality. Without retraining, the controller also supports test-time object-waypoint guidance. Qualitative results further demonstrate robust, natural contact-rich interactions and zero-shot transfer to novel object shapes. The webpage is available at https://neu-vi.github.io/LYRIC/

Touch sensing is beneficial for solving a wide variety of manipulation tasks. While there exists a wide range of tactile sensors with different properties, exploiting the fusion of multiple heterogeneous tactile sensors to improve manipulation learning remains underexplored. We present Multi-Resolution Tactile Sensing (MiTaS), a representation framework that leverages multiple tactile sensors operating at different temporal resolutions in order to solve complex contact-rich manipulation tasks. We propose a novel architecture using modality-specific convolutional stems and transformer-based fusion that effectively fuses information from an RGB camera stream, a vision-based GelSight Mini sensor and a high-frequency event-based Evetac sensor. This multi-sensor representation then conditions a flow-matching policy for solving downstream tasks. Experimental results across five contact-rich manipulation tasks demonstrate the effectiveness of multi-resolution tactile features in imitation learning. MiTaS achieves an average success rate of 80 %, while vision-only (31 %) and visual-tactile (54 %) baselines cannot solve the task reliably. Co-training a visuo-tactile model with multi-tactile data boosts performance by over 10 \% in certain tasks, without having access to the Evetac sensor during policy evaluation. A detailed sensor-reading and attention analysis reveals the importance of different sensors throughout task execution, validating our multi-resolution tactile sensing approach. Project Page: http://mitas-touch.github.io.

Recent vision-language-action (VLA) models can generate plausible end-effector motions, yet they often fail in long-horizon, contact-rich tasks because the underlying hand-object interaction (HOI) structure is not explicitly represented. An embodiment-agnostic interaction representation that captures this structure would make manipulation behaviors easier to validate and transfer across robots. We propose FlowHOI, a two-stage flow-matching framework that generates semantically grounded, temporally coherent HOI sequences, comprising hand poses, object poses, and hand-object contact states, conditioned on an egocentric observation, a language instruction, and a 3D Gaussian splatting (3DGS) scene reconstruction. We decouple geometry-centric grasping from semantics-centric manipulation, conditioning the latter on compact 3D scene tokens and employing a motion-text alignment loss to semantically ground the generated interactions in both the physical scene layout and the language instruction. To address the scarcity of high-fidelity HOI supervision, we introduce a reconstruction pipeline that recovers aligned hand-object trajectories and meshes from large-scale egocentric videos, yielding an HOI prior for robust generation. Across the GRAB and HOT3D benchmarks, FlowHOI achieves the highest action recognition accuracy and a 1.7times higher physics simulation success rate than the strongest diffusion-based baseline, while delivering a 40times inference speedup. We further demonstrate real-robot execution on four dexterous manipulation tasks, illustrating the feasibility of retargeting generated HOI representations to real-robot execution pipelines.

In this paper, we explore osmotic transport by means of molecular dynamics (MD) simulations. We first consider osmosis through a membrane, and investigate the reflection coefficient of an imperfectly semi-permeable membrane, in the dilute and high concentration regimes. We then explore the diffusion-osmotic flow of a solute-solvent fluid adjacent to a solid surface, driven by a chemical potential gradient parallel to the surface. We propose a novel non-equilibrium MD (NEMD) methodology to simulate diffusion-osmosis, by imposing an external force on every particle, which properly mimics the chemical potential gradient on the solute in spite of the periodic boundary conditions. This NEMD method is validated theoretically on the basis of linear-response theory by matching the mobility with their Green-Kubo expressions. Finally, we apply the framework to more realistic systems, namely a water-ethanol mixture in contact with a silica or a graphene surface.

Generating high-quality dexterous grasps remains challenging for learning-based methods, which often depend on carefully tuned contact losses or costly contact-based test-time refinement. We present KPGrasp, a flow-matching framework that learns dexterous grasp priors from large-scale data rather than relying on contact losses or contact-based test-time refinement. KPGrasp couples an all-Euclidean 3D hand-keypoint parameterization with a simple yet scalable Transformer flow model. The parameterization avoids the drawbacks of the conventional mixed SE(3) pose and joint-angle output space, expresses grasps in the same frame as the object point cloud, and thus enables native spatial reasoning; the Transformer flow model is trained with only the standard flow-matching loss and scales effectively with data, model capacity, and batch size. Experiments demonstrate state-of-the-art performance on two simulation benchmarks. On the Dexonomy benchmark, it reaches a 76.3% grasp success rate, improving over the strongest directly comparable baseline by 47.4% while reducing penetration depth to 2.4 mm. The same model also achieves the best average performance on the DexGrasp Anything benchmark without fine-tuning. For batched inference, KPGrasp requires only 0.032 s per grasp. Finally, real-world experiments on 20 diverse objects demonstrate that the pipeline can be deployed in a real-world setup. Project Page: https://yuansen-huang.github.io/KPGrasp-page/

We introduce CRISP, a method that recovers simulatable human motion and scene geometry from monocular video. Prior work on joint human-scene reconstruction relies on data-driven priors and joint optimization with no physics in the loop, or recovers noisy geometry with artifacts that cause motion tracking policies with scene interactions to fail. In contrast, our key insight is to recover convex, clean, and simulation-ready geometry by fitting planar primitives to a point cloud reconstruction of the scene, via a simple clustering pipeline over depth, normals, and flow. To reconstruct scene geometry that might be occluded during interactions, we make use of human-scene contact modeling (e.g., we use human posture to reconstruct the occluded seat of a chair). Finally, we ensure that human and scene reconstructions are physically-plausible by using them to drive a humanoid controller via reinforcement learning. Our approach reduces motion tracking failure rates from 55.2\% to 6.9\% on human-centric video benchmarks (EMDB, PROX), while delivering a 43\% faster RL simulation throughput. We further validate it on in-the-wild videos including casually-captured videos, Internet videos, and even Sora-generated videos. This demonstrates CRISP's ability to generate physically-valid human motion and interaction environments at scale, greatly advancing real-to-sim applications for robotics and AR/VR.

Real-world robotic assembly at sub-millimeter tolerances demands spatial precision, compliant interaction, and robustness to contact failures. We present Facet-0, a robotic foundation model that predicts and values the contact consequences of its actions. Facet-0 unifies multimodal representation learning and reinforcement learning (RL) post-training around a joint action-wrench proposal: a causal wrench history is aligned with vision-language semantics and kinematic state, and flow matching generates each action chunk together with the future wrist-wrench profile it is expected to induce. Deployment rollouts train a distributional Action-Wrench Critic to distinguish motions with similar task progress but different contact outcomes, while phase-aware rewards and contact-selective credit concentrate policy improvement on decisive interactions. To accommodate part-specific dynamics, a lightweight bounded actor reuses the frozen representation for on-robot adaptation; RL remains defined over executable Cartesian actions, while an auxiliary wrench head preserves predictive, non-commanded action-contact coupling. Trained on ManuFacet-1K, a 1,000-hour force-synchronized corpus spanning three embodiments and multiple manufacturing cells, the bounded task-adapted system reaches 82% mean success on five sub-millimeter computer-assembly tasks, compared with 15% for the strongest baseline, with 0.5 mm placement accuracy and 50 ms command latency.

Contact-rich manipulation is central to many everyday human activities, requiring continuous adaptation to contact uncertainty and external disturbances through multi-modal perception, particularly vision and tactile feedback. While imitation learning has shown strong potential for learning complex manipulation behaviors, most existing approaches rely on action chunking, which fundamentally limits their ability to react to unforeseen observations during execution. This limitation becomes especially critical in contact-rich scenarios, where physical uncertainty and high-frequency tactile feedback demand rapid, reactive control. To address this challenge, we propose Tube Diffusion Policy (TDP), a novel reactive visual-tactile policy learning framework that bridges diffusion-based imitation learning with tube-based feedback control. By leveraging the expressive power of generative models, TDP learns an observation-conditioned feedback flow around nominal action chunks, forming an action tube that enables fast and adaptive reactions during execution. We evaluate TDP on the widely used Push-T benchmark and three additional challenging visual-tactile dexterous manipulation tasks. Across all benchmarks, TDP consistently outperforms state-of-the-art imitation learning baselines. Two real-world experiments further validate its robust reactivity under contact uncertainty and external disturbances. Moreover, the step-wise correction mechanism enabled by action tube significantly reduces the required denoising steps, making TDP well suited for real-time, high-frequency feedback control in contact-rich manipulation.

Understanding how humans interact with the surrounding environment, and specifically reasoning about object interactions and affordances, is a critical challenge in computer vision, robotics, and AI. Current approaches often depend on labor-intensive, hand-labeled datasets capturing real-world or simulated human-object interaction (HOI) tasks, which are costly and time-consuming to produce. Furthermore, most existing methods for 3D affordance understanding are limited to contact-based analysis, neglecting other essential aspects of human-object interactions, such as orientation (\eg, humans might have a preferential orientation with respect certain objects, such as a TV) and spatial occupancy (\eg, humans are more likely to occupy certain regions around an object, like the front of a microwave rather than its back). To address these limitations, we introduce H2OFlow, a novel framework that comprehensively learns 3D HOI affordances -- encompassing contact, orientation, and spatial occupancy -- using only synthetic data generated from 3D generative models. H2OFlow employs a dense 3D-flow-based representation, learned through a dense diffusion process operating on point clouds. This learned flow enables the discovery of rich 3D affordances without the need for human annotations. Through extensive quantitative and qualitative evaluations, we demonstrate that H2OFlow generalizes effectively to real-world objects and surpasses prior methods that rely on manual annotations or mesh-based representations in modeling 3D affordance.

Contact-rich manipulation requires policies to react to local deformation, pressure, slip, and friction, yet these cues are temporally sparse and often invisible in visual observations. Existing visual-tactile policies usually feed tactile observations directly into action prediction, but rarely model tactile deformation dynamics during action generation. In this paper, we introduce VT-WAM, a Visual-Tactile World Action Model that jointly learns future visual prediction, tactile deformation prediction, and action prediction within a unified flow matching framework. In particular, VT-WAM introduces (1) Asymmetric Mixture-of-Transformers (MoT) attention to bridge a first-frame visual anchor with temporal tactile dynamics, and (2) contact-gated Action-Visual-Tactile Attention Guidance (AVTAG) to encourage action queries to rely on tactile evidence during contact phases. Across six real-world contact-rich manipulation tasks, VT-WAM achieves a 71.67% average success rate, outperforming Fast-WAM by 26.67% and OmniVTLA by 35.84%. Ablations demonstrate that modeling tactile deformation dynamics and guiding contact-phase tactile attention are both important for contact-rich tasks. Project website: https://vt-wam.github.io/.

Dexterous manipulation involves contact-rich and fine-grained interactions with the physical world, posing significant challenges for existing vision-language-action (VLA) models due to severe visual occlusions and complex contact dynamics. While recent works have incorporated tactile sensing into robotic manipulation, most approaches still rely on homogeneous multimodal fusion, lacking adaptive tactile integration and explicit modeling of physical dynamics. In this work, we present DeCAL, a physically-grounded dexterous vision-language-action model that unifies understanding, imagination and action generation for contact-rich dexterous manipulation. Built upon a Mixture-of-Transformers (MoT) architecture, DeCAL leverages specialized experts for each capability while enabling efficient information flow among them. To effectively leverage tactile information, we introduce Adaptive Visuo-Tactile Fusion that dynamically regulates tactile interactions via a contact-aware gating strategy. Furthermore, we propose Visuo-Tactile Latent Co-Imagination to jointly model visual and tactile dynamics, equipping the policy with implicit physical world knowledge. Experimental results show that DeCAL consistently achieves state-of-the-art performance across all tasks, attaining a 71% average success rate and an 83.4% progress success rate, while also demonstrating strong generalization to unseen scenarios. The website is available at https://aureleopku.github.io/DeCAL.

Hypothesis: Bacterial contamination of surfaces poses a major threat to public health. Designing effective antibacterial or self-cleaning surfaces requires understanding how bacteria-laden droplets interact with solid substrates and how readily they can be removed. We hypothesize that bacterial motility critically influences the early-stage surface interaction (i.e., surface adhesion) of bacteria-laden droplets, which cannot be captured by conventional contact angle goniometry. Experiments: Sessile droplets containing live and dead Escherichia coli (E. coli) were studied to probe their wetting and interfacial behavior. Contact angle goniometry was used to probe dynamic wetting, while a cantilever-deflection-based method was used to quantify adhesion. Internal flow dynamics were visualized using micro-particle image velocimetry (PIV) and analyzed statistically. Complementary sliding experiments on moderately wettable substrates were performed to assess contact line mobility under tilt. Findings: Despite lower surface tension, droplets containing live bacteria exhibited lower surface adhesion forces than their dead counterparts, with adhesion further decreasing at higher bacterial concentrations. Micro-PIV revealed that flagellated live E. coli actively resist evaporation-driven capillary flow via upstream migration, while at higher concentrations, collective dynamics emerge, producing spatially coherent bacterial motion despite temporal variability. These coordinated flows disrupt passive transport and promote depinning of the contact line, thereby reducing adhesion. Sliding experiments confirmed enhanced contact line mobility and frequent stick-slip motion in live droplets, even with lower receding contact angles and higher hysteresis. These findings provide mechanistic insight into droplet retention, informing the design of self-cleaning/antifouling surfaces.

Reconstructing 3D Human-Object Interaction from an RGB image is essential for perceptive systems. Yet, this remains challenging as it requires capturing the subtle physical coupling between the body and objects. While current methods rely on sparse, binary contact cues, these fail to model the continuous proximity and dense spatial relationships that characterize natural interactions. We address this limitation via InterFields, a representation that encodes dense, continuous proximity across the entire body and object surfaces. However, inferring these fields from single images is inherently ill-posed. To tackle this, our intuition is that interaction patterns are characteristically structured by the action and object geometry. We capture this structure in LEXIS, a novel discrete manifold of interaction signatures learned via a VQ-VAE. We then develop LEXIS-Flow, a diffusion framework that leverages LEXIS signatures to estimate human and object meshes alongside their InterFields. Notably, these InterFields help in a guided refinement that ensures physically-plausible, proximity-aware reconstructions without requiring post-hoc optimization. Evaluation on Open3DHOI and BEHAVE shows that LEXIS-Flow significantly outperforms existing SotA baselines in reconstruction, contact, and proximity quality. Our approach not only improves generalization but also yields reconstructions perceived as more realistic, moving us closer to holistic 3D scene understanding. Code & models will be public at https://anticdimi.github.io/lexis.

Implicit Neural Spatial Representation (INSR) has emerged as an effective representation of spatially-dependent vector fields. This work explores solving time-dependent PDEs with INSR. Classical PDE solvers introduce both temporal and spatial discretizations. Common spatial discretizations include meshes and meshless point clouds, where each degree-of-freedom corresponds to a location in space. While these explicit spatial correspondences are intuitive to model and understand, these representations are not necessarily optimal for accuracy, memory usage, or adaptivity. Keeping the classical temporal discretization unchanged (e.g., explicit/implicit Euler), we explore INSR as an alternative spatial discretization, where spatial information is implicitly stored in the neural network weights. The network weights then evolve over time via time integration. Our approach does not require any training data generated by existing solvers because our approach is the solver itself. We validate our approach on various PDEs with examples involving large elastic deformations, turbulent fluids, and multi-scale phenomena. While slower to compute than traditional representations, our approach exhibits higher accuracy and lower memory consumption. Whereas classical solvers can dynamically adapt their spatial representation only by resorting to complex remeshing algorithms, our INSR approach is intrinsically adaptive. By tapping into the rich literature of classic time integrators, e.g., operator-splitting schemes, our method enables challenging simulations in contact mechanics and turbulent flows where previous neural-physics approaches struggle. Videos and codes are available on the project page: http://www.cs.columbia.edu/cg/INSR-PDE/

Reinforcement learning explores effectively in domains such as Atari games, navigation, and locomotion, where novelty over states or dynamics is a sufficient signal. In contrast, dexterous manipulation requires rich physical hand--object interactions, but existing methods often suffer from unstable contact-based novelty signals, inefficient distance novelty signals, or reliance on task-specific priors. We propose ContactExplorer, a general exploration method for dexterous manipulation tasks. ContactExplorer represents contact as the intersection between object surface points and hand keypoints, encouraging dexterous hands to discover diverse and novel contact patterns, namely which fingers contact which object regions. It maintains a contact counter conditioned on discretized object states obtained via learned hash codes. This counter is leveraged in two complementary ways: (1) a count-based contact coverage reward that promotes exploration of novel contact patterns, and (2) an energy-based reaching reward that guides the agent toward under-explored contact regions. We evaluate ContactExplorer on seven contact-rich manipulation tasks and five dexterous hand embodiments. Experimental results show that ContactExplorer substantially improves sample efficiency and success rates over existing exploration methods, that it reduces the need for task-specific priors, and that it remains effective across hand embodiments and transfers to the real world. Project page is https://contact-explorer.github.io.

Cells that collide with each other repolarize away from contact, in a process called contact inhibition of locomotion (CIL), which is necessary for correct development of the embryo. CIL can occur even when cells make a micron-scale contact with a neighbor - much smaller than their size. How precisely can a cell sense cell-cell contact and repolarize in the correct direction? What factors control whether a cell recognizes it has contacted a neighbor? We propose a theoretical model for the limits of CIL where cells recognize the presence of another cell by binding the protein ephrin with the Eph receptor. This recognition is made difficult by the presence of interfering ligands that bind nonspecifically. Both theoretical predictions and simulation results show that it becomes more difficult to sense cell-cell contact when it is difficult to distinguish ephrin from the interfering ligands, or when there are more interfering ligands, or when the contact width decreases. However, the error of estimating contact position remains almost constant when the contact width changes. This happens because the cell gains spatial information largely from the boundaries of cell-cell contact. We study using statistical decision theory the likelihood of a false positive CIL event in the absence of cell-cell contact, and the likelihood of a false negative where CIL does not occur when another cell is present. Our results suggest that the cell is more likely to make incorrect decisions when the contact width is very small or so large that it nears the cell's perimeter. However, in general, we find that cells have the ability to make reasonably reliable CIL decisions even for very narrow (micron-scale) contacts, even if the concentration of interfering ligands is ten times that of the correct ligands.

We introduce Lagrangian Flow Networks (LFlows) for modeling fluid densities and velocities continuously in space and time. By construction, the proposed LFlows satisfy the continuity equation, a PDE describing mass conservation in its differentiable form. Our model is based on the insight that solutions to the continuity equation can be expressed as time-dependent density transformations via differentiable and invertible maps. This follows from classical theory of the existence and uniqueness of Lagrangian flows for smooth vector fields. Hence, we model fluid densities by transforming a base density with parameterized diffeomorphisms conditioned on time. The key benefit compared to methods relying on numerical ODE solvers or PINNs is that the analytic expression of the velocity is always consistent with changes in density. Furthermore, we require neither expensive numerical solvers, nor additional penalties to enforce the PDE. LFlows show higher predictive accuracy in density modeling tasks compared to competing models in 2D and 3D, while being computationally efficient. As a real-world application, we model bird migration based on sparse weather radar measurements.

This paper presents a novel object-centric contact representation ContactGen for hand-object interaction. The ContactGen comprises three components: a contact map indicates the contact location, a part map represents the contact hand part, and a direction map tells the contact direction within each part. Given an input object, we propose a conditional generative model to predict ContactGen and adopt model-based optimization to predict diverse and geometrically feasible grasps. Experimental results demonstrate our method can generate high-fidelity and diverse human grasps for various objects. Project page: https://stevenlsw.github.io/contactgen/

Recent advances in artificial intelligence (AI) have produced highly capable and controllable systems. This creates unprecedented opportunities for structured reasoning as well as collaboration among multiple AI systems and humans. To fully realize this potential, it is essential to develop a principled way of designing and studying such structured interactions. For this purpose, we introduce the conceptual framework of Flows: a systematic approach to modeling complex interactions. Flows are self-contained building blocks of computation, with an isolated state, communicating through a standardized message-based interface. This modular design allows Flows to be recursively composed into arbitrarily nested interactions, with a substantial reduction of complexity. Crucially, any interaction can be implemented using this framework, including prior work on AI--AI and human--AI interactions, prompt engineering schemes, and tool augmentation. We demonstrate the potential of Flows on the task of competitive coding, a challenging task on which even GPT-4 struggles. Our results suggest that structured reasoning and collaboration substantially improve generalization, with AI-only Flows adding +21 and human--AI Flows adding +54 absolute points in terms of solve rate. To support rapid and rigorous research, we introduce the aiFlows library. The library comes with a repository of Flows that can be easily used, extended, and composed into novel, more complex Flows. The aiFlows library is available at https://github.com/epfl-dlab/aiflows. Data and Flows for reproducing our experiments are available at https://github.com/epfl-dlab/cc_flows.

Numerous biological and physical processes can be modeled as systems of interacting entities evolving continuously over time, e.g. the dynamics of communicating cells or physical particles. Learning the dynamics of such systems is essential for predicting the temporal evolution of populations across novel samples and unseen environments. Flow-based models allow for learning these dynamics at the population level - they model the evolution of the entire distribution of samples. However, current flow-based models are limited to a single initial population and a set of predefined conditions which describe different dynamics. We argue that multiple processes in natural sciences have to be represented as vector fields on the Wasserstein manifold of probability densities. That is, the change of the population at any moment in time depends on the population itself due to the interactions between samples. In particular, this is crucial for personalized medicine where the development of diseases and their respective treatment response depends on the microenvironment of cells specific to each patient. We propose Meta Flow Matching (MFM), a practical approach to integrating along these vector fields on the Wasserstein manifold by amortizing the flow model over the initial populations. Namely, we embed the population of samples using a Graph Neural Network (GNN) and use these embeddings to train a Flow Matching model. This gives MFM the ability to generalize over the initial distributions unlike previously proposed methods. We demonstrate the ability of MFM to improve prediction of individual treatment responses on a large scale multi-patient single-cell drug screen dataset.

We verify a recent prediction (Eq. 3.50 in G. L. Eyink, Phys. Rev. X 11, 031054 (2021)) for the drag on an object moving through a fluid. In this prediction the velocity field is decomposed into a nonvortical (potential) and vortical contribution, and so is the associated drag force. In the Josephson-Anderson relation the vortical contribution of the drag force follows from the flux of vorticity traversing the streamlines of the corresponding potential flow. The potential component is directly determined by the plate acceleration and its added mass. The Josephson-Anderson relation is derived from the quantum description of superfluids, but remarkably applies to the classical fluid in our experiment. In our experiment a flat plate is accelerated through water using a robotic arm. This geometry is simple enough to allow analytic potential flow streamlines. The monitored plate position shows an oscillatory component of the acceleration, which adds an additional test of the Josephson-Anderson relation. The instantaneous velocity field is measured using particle image velocimetry. It enables us to evaluate Eq. 3.50 from [1] and compare its prediction to the measured drag force. We find excellent agreement, and, most remarkably find that the added mass contribution to the drag force still stands out after the flow has turned vortical. We finally comment on the requirements on the experimental techniques for evaluating the Josephson-Anderson relation.

Daily activities require humans to coordinate whole-body motion with the motion of surrounding objects. Despite recent progress in human-object interaction (HOI) generation, most existing methods assume interactions with a single rigid object and do not extend well to scenarios involving a variable number of objects or articulated objects with diverse joint mechanisms. We propose surface keypoint trajectories as an object motion representation: for each rigid component, whether a standalone object or one part of an articulated assembly, we track a small set of non-collinear surface points over time. This representation handles multi-object coordination and diverse articulation mechanisms directly from point dynamics without requiring explicit joint-type specification. To model when and where each body region contacts each object, we introduce a spatio-temporal contact distance field that extends distance-based contact modeling to whole-body, multi-object, and articulated settings. We factorize HOI generation into three stages: generating object motions from text or waypoints, predicting the contact distance field, and synthesizing whole-body motion with contact-guided optimization. Experiments on ParaHome, HIMO, ARCTIC, and OMOMO demonstrate better or comparable performance to existing methods across single-object, multi-object, and articulated interaction settings.

Contact often occurs without macroscopic surface deformation, such as during interaction with liquids, semi-liquids, or ultra-soft materials. However, most existing tactile sensors rely on deformation to infer contact, making such light-contact interactions difficult to perceive robustly. To address this, we present LightTact, a visual-tactile fingertip sensor that makes contact directly visible via a deformation-independent principle. LightTact features an ambient-blocking optical configuration that suppresses both external light and internal illumination at non-contact regions, while transmitting only the scattered light generated at true contacts. As a result, LightTact produces high-contrast raw images in which non-contact pixels remain near-black (mean gray value < 3) and contact pixels preserve the natural appearance of the contacting surface. Built on this, LightTact achieves accurate pixel-level contact segmentation that is robust to material properties, contact force, surface appearance, and environmental lighting. We further demonstrate that LightTact unlocks new robotic manipulation behaviors that require detection of extremely light contact, including water spreading, facial-cream dipping, and soft thin-film interaction. In addition, we show that LightTact's spatially aligned visual-tactile images can be directly interpreted by vision-language models.

Neural Flows efficiently model irregular multivariate time series by directly learning ODE solution trajectories with neural networks, bypassing step-by-step numerical solvers. Despite their efficiency, many existing approaches treat variables independently, leaving inter-variable interactions underexplored. Moreover, their one-step mapping makes interaction modeling inherently challenging, as it removes the iterative refinement of interactions during learning. To address this challenge, we propose one-step Graph-Structured Neural Flows (GSNF), which introduce two auxiliary-trajectory self-supervision strategies to strengthen interaction learning: (i) interaction-aware trajectory generation via re-initialization, which induces trajectory divergence to expose graph-induced interactions, with a theoretically derived lower bound on divergence; and (ii) reverse-time trajectory generation, which enforces forward-backward consistency to regularize graph learning, enabled by flow invertibility. Experiments on five real-world datasets show that GSNF achieves state-of-the-art classification performance with highly competitive training time and memory usage.