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PMC12776500
41510274
10.21203/rs.3.rs-8283811/v1
Local Misalignment Scoring Reveals Spatially Uniform Chondrocyte Disorganization in a Wnt5a-C83S Knock-in Model of Robinow Syndrome.
The WNT5A-mediated Wnt/Planar Cell Polarity (Wnt/PCP) pathway plays a key role in vertebrate development, particularly in limb morphogenesis. Robinow Syndrome (RS) is a rare genetic disorder characterized primarily by craniofacial malformations and limb shortening that is linked to mutations in multiple Wnt/PCP genes. ...
Research square
2025
Res Sq. 2025 Dec 17:rs.3.rs-8283811. Preprint. [Version 1] doi: 10.21203/rs.3.rs-8283811/v1
CC BY
[ "Journal Article", "Preprint" ]
[ "Zhong ZA", "Michalski MN", "Diegel CR", "Christie C", "Klamer Z", "Lanning NJ", "Haab BB", "Grainger S", "Williams BO" ]
PMC12796841
41536519
10.1002/mco2.70548
Emestrin-Type Epidithiodiketopiperazines Inhibited Gasdermin D-Mediated Pyroptosis via Caspase-3/7 Activation.
Sepsis, a life-threatening dysregulated host response to infection, is frequently exacerbated by pyroptosis-a programmed, proinflammatory cell death process mediated by Gasdermin D (GSDMD) activation. Using high-throughput screening, we identified emestrin-type epidithiodiketopiperazines (ETPs) as potent inhibitors of ...
MedComm
2026
MedComm (2020). 2026 Jan 13;7(1):e70548. doi: 10.1002/mco2.70548
CC BY
[ "Journal Article" ]
[ "Geng B", "Lin S", "Yim WY", "Sun W", "Zhang X", "Ma C", "Zhang Z", "Guo Q", "Gao J", "Zeng H", "Tong Q", "Wang Y", "Fan Z", "Hou J", "Li M", "Zhang Y", "Hu Z" ]
PMC12779654
39264546
10.1007/s10912-024-09896-4
The Poetic Wavelength-Tuning into the Meaningful Poetics of Psychosis.
Despite the emerging evidence base to support the therapeutic potential of creative writing and poetry for a variety of mental health problems, the therapeutic potential of poetry for people who have experienced psychosis remains poorly understood. The paper argues that by considering psychosis as meaningful poetics, t...
The Journal of medical humanities
2025
J Med Humanit. 2024 Sep 12;46(4):729–36. doi: 10.1007/s10912-024-09896-4
CC BY
[ "Journal Article" ]
[ "Pearson M" ]
PMC12764991
41331012
10.1038/s41598-025-28807-8
The effect of humic acid in composition with polyacrylamide copolymers on wind and water soil erosion.
The present study, for the first time, the optical, electrokinetic, and mechanical properties of humic acid (HA) extracted from brown coal of the Shubarkul deposit (Kazakhstan) were investigated in combination with anionic and cationic polyacrylamide copolymers. These polymers were employed as novel, environmentally fr...
Scientific reports
2025
Sci Rep. 2025 Dec 2;16:139. doi: 10.1038/s41598-025-28807-8
CC BY
[ "Journal Article" ]
[ "Bekturganova NY", "Mirzaeian M" ]
PMC12785412
41516053
10.3390/ijms27010175
Oxidative Stress, Mitochondrial Homeostasis, and Sirtuins in Atrial Fibrillation.
Atrial fibrillation (AF) is the most common cardiac arrhythmia. Yet, its treatment has serious challenges and is unsuccessful in a considerable fraction of patients. One reason may be a limited understanding of the molecular mechanisms underlying AF. Recent studies suggest that oxidative stress is involved in AF pathog...
International journal of molecular sciences
2025
Int J Mol Sci. 2025 Dec 23;27(1):175. doi: 10.3390/ijms27010175
CC BY
[ "Journal Article", "Review" ]
[ "Krekora J", "Pawlowska E", "Derwich M", "Drożdż J", "Blasiak J" ]
PMC12784349
41004172
10.1042/BSR20253737
High expression of Fgr in the left ventricle attenuates myocardial injury in the infarcted region via regulating the phosphorylation level of PI3K/Akt.
FGR proto-oncogene (Fgr), a member of the Src family kinases, has garnered attention for its potential involvement in apoptotic signaling, yet its role in cardiovascular diseases, particularly acute myocardial infarction (AMI), remains unexplored. This study sought to investigate whether elevated left ventricular Fgr e...
Bioscience reports
2025
Biosci Rep. 2025 Oct 13;45(10):615–33. doi: 10.1042/BSR20253737
CC BY
[ "Journal Article" ]
[ "Shao D", "Zhang Z", "Ji H", "Shi L" ]
PMC12778352
41510341
10.1298/ptr.25-E10371
Reliability of Resting Heart Rate-based Target Heart Rate for Exercise Prescription after Acute Myocardial Infarction.
OBJECTIVES: Anaerobic threshold (AT) assessment using cardiopulmonary exercise testing (CPX) during hospitalization is considered ideal for prescribing exercise regimens in patients with acute myocardial infarction (AMI). However, practical limitations often hinder its implementation. This study evaluated strategies fo...
Physical therapy research
2025
Phys Ther Res. 2025 Nov 22;28(3):206–14. doi: 10.1298/ptr.25-E10371
CC BY
[ "Journal Article" ]
[ "Utsumi Y", "Takase K", "Murakami N", "Nakagawa T", "Obayashi T", "Ogura R", "Hosokawa S" ]
PMC12798524
41662066
10.1371/journal.pmen.0000434
The relationship between ambivalence over the expression of emotions and somatic symptoms among Iranian long-distance and geographically close partners: The mediating role of emotional suppression.
Previous research has shown that difficulties in emotional expression may be linked to physical health symptoms, but few studies have explored this in the context of romantic relationship types. This study investigates the role of emotional suppression as a mediator between emotional ambivalence and somatic symptoms in...
PLOS mental health
2025
PLOS Ment Health. 2025 Oct 15;2(10):e0000434. doi: 10.1371/journal.pmen.0000434
CC BY
[ "Journal Article" ]
[ "Okati N", "Rangamiztoosi L", "Gholipour M", "Zarani F" ]
PMC12768194
41497089
10.1097/MS9.0000000000004345
Organoid models to predict chemotherapy response and guide surgical strategy in pancreatic cancer.
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, with limited predictive biomarkers for chemotherapy response. Patient-derived organoids (PDOs), developed from endoscopic or surgical samples, faithfully replicate tumor genetics and microarchitecture, allowing rapid ex vivo drug testi...
Annals of medicine and surgery (2012)
2026
Ann Med Surg (Lond). 2025 Nov 14;88(1):1007–8. doi: 10.1097/MS9.0000000000004345
CC BY
[ "Letter" ]
[ "Aminpoor H", "Zaib M", "Khizar M", "Alamgeer M", "Karimi H" ]
PMC12783806
41507135
10.1038/s41420-025-02855-5
Exosome-transmitted long noncoding RNA SNHG1 promotes prostate cancer bone metastasis via YBX1/MMP16 axis.
Prostate cancer (PCa) patients with bone metastasis commonly exhibit osteoblastic-type and have an extremely poor prognosis. Exosomes derived from tumor cells possess biological significance and can mediate intercellular communication in the tumor microenvironment. Long noncoding RNA (lncRNA) small nucleolar RNA host g...
Cell death discovery
2026
Cell Death Discov. 2026 Jan 8;12:7. doi: 10.1038/s41420-025-02855-5
CC BY
[ "Journal Article" ]
[ "Yang T", "Luo J", "Long Z", "Wu J", "Chen W", "Zhou X", "Zou L", "Cen S", "Zhong C", "Lu J", "Zheng P", "Wei A", "Lv D", "Mao X" ]
PMC12774340
41493990
10.1371/journal.pone.0340093
Spatial distribution and determinants of fertility preferences among female adolescents and young adults in Ethiopia.
INTRODUCTION: Understanding adolescents and young adults' (AYAs) fertility preferences is crucial for guiding youth-focused family planning and predicting future fertility. However, fertility preference determinants and spatial patterns among Ethiopian AYAs remain underexplored. This study examines the spatial distribu...
PloS one
2026
PLoS One. 2026 Jan 6;21(1):e0340093. doi: 10.1371/journal.pone.0340093
CC BY
[ "Journal Article" ]
[ "Alemu MB", "Lassi ZS", "Alemu SB", "Ebrahim AB", "Belay DG", "Tessema GA" ]
PMC12787852
41516509
10.3390/s26010074
High-Efficiency Traceability Mechanism for Multimedia Data in Consumer Internet of Things Combined with Blockchain.
In the context of the rapid development of Consumer Internet of Things (CIoT), the manipulation and unauthorized distribution of multimedia content have raised serious concerns regarding copyright protection and data authenticity. Ensuring secure traceability and authenticity in complex network environments remains a m...
Sensors (Basel, Switzerland)
2025
Sensors (Basel). 2025 Dec 22;26(1):74. doi: 10.3390/s26010074
CC BY
[ "Journal Article" ]
[ "Yan T", "Chen J", "Zhang X", "Hu G" ]
PMC12785137
41514731
10.3390/ani16010043
Effects of Rumen-Protected β-Alanine on Growth Performance, Rumen Microbiome, and Serum Metabolome of Beef Cattle.
β-alanine has been shown to significantly improve nitrogen utilization efficiency in beef cattle, but its impact on growth performance remains unclear. This study involved 36 healthy 18-month-old Simmental crossbred bulls with similar weights (627 ± 41 kg). The cattle were divided into two groups, with each group compr...
Animals : an open access journal from MDPI
2025
Animals (Basel). 2025 Dec 24;16(1):43. doi: 10.3390/ani16010043
CC BY
[ "Journal Article" ]
[ "Fu D", "Mao K", "Zang Y", "Qu M", "Qiu Q", "Zhao X", "Ouyang K", "Li Y" ]
PMC12766678
41497416
10.1021/acselectrochem.5c00227
Nanomaterial Modification of Ultramicroelectrodes Using Design-of-Experiments Principles.
Modification of ultramicroelectrode sensors with electroactive nanomaterials is key to enhancing their microscale sensing performance for advanced applications in cellular biology, disease diagnostics, or scanning electrochemical microscopy (SECM). This work employs a modern design-of-experiment (DoE) approach to devel...
ACS electrochemistry
2026
ACS Electrochem. 2025 Nov 27;2(1):101–12. doi: 10.1021/acselectrochem.5c00227
CC BY
[ "Journal Article" ]
[ "Bocking RA", "Dixon TM", "Parke B", "Hashemi P", "Bourne RA", "Actis P", "Menzel R" ]
PMC12796725
41456278
10.1016/j.xpro.2025.104252
Protocol to assess retinal metabolic flux of mice via stable isotope-resolved metabolomics.
Here, we present a protocol for evaluating glucose metabolism in mouse retinas and retinal pigment epithelium (RPE)-choroid tissue by tracking the incorporation of 13C6 from U-13C6-glucose with gas chromatography-mass spectrometry (GC-MS). We describe steps for incubating tissues in Krebs-Ringer bicarbonate solution an...
STAR protocols
2026
STAR Protoc. 2025 Dec 27;7(1):104252. doi: 10.1016/j.xpro.2025.104252
CC BY
[ "Journal Article" ]
[ "Komissarov G", "Pandey K", "Nolan ND", "Winogrodzki T", "Hass DT", "Demirkol A", "Robbings BM", "Hurley JB", "Tsang SH" ]
PMC12758196
41459728
10.1080/19490976.2025.2604908
Crosstalk between the microbiota and intestinal γδ T cell compartments in health and IBD.
Unconventional T cells expressing the γδ T cell receptor (TCR) are abundant within the intestine and largely function as 'first responders' to injury, infection and inflammation. To this end, murine γδ T cells are highly compartmentalized within the intestinal mucosa based on the expression of their Vγ chain and their ...
Gut microbes
2026
Gut Microbes. 2025 Dec 29;18(1):2604908. doi: 10.1080/19490976.2025.2604908
CC BY
[ "Journal Article", "Review", "Research Support, N.I.H., Extramural" ]
[ "Parthasarathy A", "Li T", "Edelblum KL" ]
PMC12789846
41190378
10.1111/bju.70067
Prostate zonal impact of 5α-reductase inhibitors on multiparametric MRI characteristics and detection of prostate cancer.
OBJECTIVES: To assess the impact of 5α-reductase inhibitors (5-ARIs) on multiparametric magnetic resonance imaging (mpMRI) features of Prostate Imaging-Reporting and Data System (PI-RADS) lesions and their influence on the detection of clinically significant prostate cancer (csPCa), with a focus on differences between ...
BJU international
2026
BJU Int. 2025 Nov 5;137(2):332–8. doi: 10.1111/bju.70067
CC BY
[ "Journal Article", "Multicenter Study" ]
[ "Das A", "Bigarella M", "Brackman K", "Allen GO", "Rais-Bahrami S", "Bahr K", "Schmitt E", "Fang AM", "Boudreau H", "Filson CP", "Pectasides M", "Toia GV", "Jarrard DF" ]
PMC12764162
41291732
10.1186/s12967-025-07448-5
Lipid deprivation amplifies type I IFN responses in monocytes through prenylation: insights from familial combined hypolipidemia type 2.
Familial Combined Hypolipidemia (FHBL2) is a genetic disorder caused by loss-of-function mutations in the Angiopoietin-like 3 (ANGPTL3) gene. FHBL2 subjects exhibit hypolipidemia and protection from atherosclerotic cardiovascular diseases. Here, we explored the hypothesis that immunometabolic events contribute to this ...
Journal of translational medicine
2025
J Transl Med. 2025 Nov 25;24:3. doi: 10.1186/s12967-025-07448-5
CC BY
[ "Journal Article" ]
[ "Pinzon Grimaldos A", "Pacella I", "Giacomelli T", "Bini S", "Di Costanzo A", "Minicocci I", "D'Erasmo L", "Pietropaolo G", "Licursi V", "Arca M", "Piconese S" ]
PMC12786121
41511296
10.3390/cells15010012
The Knockout of PEX11a Results in Mild Peroxisomal Dysfunction and Lowered Cardiac Recovery Following Langendorff-Mediated Ischemia-Reperfusion in Mice.
Peroxisomal biogenesis defects frequently trigger processes of remodeling, increased oxidative stress and metabolic dysregulations that cause cellular dysfunction. Despite extensive research into cardiomyocyte ultrastructure and metabolism, knowledge on peroxisomal function in these cells is scarce. The objective of th...
Cells
2025
Cells. 2025 Dec 20;15(1):12. doi: 10.3390/cells15010012
CC BY
[ "Journal Article" ]
[ "Colasante C", "Chen J", "Garikapati V", "Spengler B", "Schlüter KD", "Baumgart-Vogt E" ]
PMC12788679
41511922
10.1371/journal.pone.0324114
Community management: An effective model to reduce medication discontinuation rate in patients with schizophrenia.
BACKGROUND: Medication discontinuation is highly prevalent among patients with schizophrenia and is associated with poor clinical outcomes. Although community-based management models have been implemented in China to support patients, recent evidence of their effectiveness in reducing medication discontinuation rates r...
PloS one
2026
PLoS One. 2026 Jan 9;21(1):e0324114. doi: 10.1371/journal.pone.0324114
CC BY
[ "Journal Article" ]
[ "Ren H", "Yang Q", "He C", "Jiao J", "Dong Z" ]
PMC12758677
41481543
10.1371/journal.pone.0319883
Variation in exposure in neighborhoods of Dhaka, Bangladesh across different environmental pathways: The influence of human behavior on fecal exposure in urban environments.
BACKGROUND: Poor sanitation and fecal sludge management contribute to fecal contamination in Dhaka's urban environment. An exposure assessment through ten environmental pathways was conducted using the SaniPathTM tool to understand the exposure to fecal contamination. METHODS: Data collection took place from 25/04/2017...
PloS one
2026
PLoS One. 2026 Jan 2;21(1):e0319883. doi: 10.1371/journal.pone.0319883
CC BY
[ "Journal Article", "Research Support, Non-U.S. Gov't" ]
[ "Amin N", "Raj S", "Green J", "Ali S", "Haque S", "Wang Y", "Mairinger W", "Ahmed T", "Joseph G", "Rahman M", "Moe CL" ]
PMC12794621
41531461
10.1093/femsml/uqaf045
Obligate heterotrophy of hyperthermophilic archaea Pyrobaculum arsenaticum and P. aerophilum.
Pyrobaculum arsenaticum and P. aerophilum are two hyperthermophiles that belong to the phylum Thermoproteota (also known as Crenarchaeota), order Thermoproteales. Pyrobaculum arsenaticum is an obligate anaerobe, whereas P. aerophilum is a facultatively aerobic organism. Both species have been described as capable of au...
microLife
2026
Microlife. 2025 Dec 27;7:uqaf045. doi: 10.1093/femsml/uqaf045
CC BY
[ "Journal Article" ]
[ "Pettinato E", "Steiner TM", "Seitz C", "Huber H", "Eisenreich W", "Berg IA" ]
PMC12757022
41477822
10.1126/sciadv.ady0812
Membrane microdomains are crucial for Mycobacterium marinum EsxA-dependent membrane damage, escape to the cytosol, and infection.
Mycobacterium tuberculosis disrupts the membrane of the Mycobacterium-containing vacuole (MCV) via its EsxA virulence factor, secreted via the ESX-1 system. We identified how pathogenic Mycobacterium marinum exploits host sterol-rich membrane microdomains to induce MCV damage during infection of Dictyostelium discoideu...
Science advances
2026
Sci Adv. 2026 Jan 1;12(1):eady0812. doi: 10.1126/sciadv.ady0812
CC BY
[ "Journal Article" ]
[ "Perret A", "Bosmani C", "Leuba F", "Eblighatian K", "Guého A", "Raykov L", "Hanna N", "Soldati T" ]
PMC12770928
41503490
10.1039/d5ra09710j
Engineering half-metallicity in wurtzite Zn1-2x Mn x A x S (A = Mo, Ni) for enhanced optoelectronic and thermoelectric performance: a DFT study.
The electronic, magnetic, optical, and thermoelectric properties of the artificially engineered (Mn, Mo) and (Mn, Ni) codoped ZnS systems have been investigated using density functional theory (DFT) within the Wien2K Package. Calculations were carried out using both the generalized gradient approximation (GGA) and the ...
RSC advances
2026
RSC Adv. 2026 Jan 6;16(2):1622–42. doi: 10.1039/d5ra09710j
CC BY
[ "Journal Article" ]
[ "Amghar W", "Lamrani AF", "Sadki K", "El Mabchour FE", "Maskar E", "El Hat A", "Otmani S", "Laamara RA" ]
PMC12783366
41159507
10.1177/00099228251382047
What Are We Missing? SEEKing Expanded Support for Health-Related Social Needs.
Psychosocial screening is inconsistently administered in pediatric primary care and rarely includes older children. This cross-sectional study compares screening outcomes from and interventions related to expanded use of the safe environment for every kid (SEEK) approach in children aged 0 to 17 versus the usual applic...
Clinical pediatrics
2026
Clin Pediatr (Phila). 2025 Oct 29;65(2):254–62. doi: 10.1177/00099228251382047
CC BY
[ "Journal Article", "Research Support, N.I.H., Extramural", "Research Support, Non-U.S. Gov't" ]
[ "Spotts RL", "Snyder-Vyas AN", "Emrick C", "Grey K", "Schaefer E", "Dubowitz H", "Fogel BN" ]
PMC12787035
41516410
10.3390/ijms27010540
Endothelin-2 and Its Association with Uric Acid Levels and Systemic Inflammation: Relevance to Chronic Kidney Disease Progression.
Chronic kidney disease (CKD) is associated with chronic inflammation and metabolic dysregulation. While endothelin-1 (ET-1) has been extensively studied, the role of endothelin-2 (ET-2) in CKD remains poorly understood. This cross-sectional study included 76 participants, 12 healthy controls and 64 CKD patients, strati...
International journal of molecular sciences
2026
Int J Mol Sci. 2026 Jan 5;27(1):540. doi: 10.3390/ijms27010540
CC BY
[ "Journal Article" ]
[ "Blazhev AB", "Kostov K", "Ignatov BI", "Eftimova T", "Simeonova TN", "Blazheva SO" ]
PMC12758743
41481608
10.1371/journal.ppat.1013822
Broadly neutralizing antibody responses in a Chinese acute HIV-1 infection cohort of men who have sex with men.
Numerous broadly neutralizing antibodies (bnAbs) have been isolated from individuals with chronic HIV-1 infection, yet eliciting bnAbs through active immunization remains challenging. Investigating naturally infected patients whose plasma exhibits broadly neutralizing activity may reveal the factors driving bnAb develo...
PLoS pathogens
2026
PLoS Pathog. 2026 Jan 2;22(1):e1013822. doi: 10.1371/journal.ppat.1013822
CC BY
[ "Journal Article", "Research Support, Non-U.S. Gov't" ]
[ "Yao L", "Gao Y", "Tian W", "Ding H", "Shang H", "Han X" ]
PMC12772937
41493946
10.2196/72101
Performance of a Small Language Model Versus a Large Language Model in Answering Glaucoma Frequently Asked Patient Questions: Development and Usability Study.
BACKGROUND: Large language models (LLMs) have been shown to answer patient questions in ophthalmology similar to human experts. However, concerns remain regarding their use, particularly related to patient privacy and potential inaccuracies that could compromise patient safety. OBJECTIVE: This study aimed to compare th...
JMIR AI
2026
JMIR AI. 2026 Jan 6;5:e72101. doi: 10.2196/72101
CC BY
[ "Journal Article" ]
[ "Faneli AC", "Scherer R", "Muralidhar R", "Guerreiro-Filho M", "Beniz L", "Vilasboas-Campos V", "Costa D", "Jammal AA", "Medeiros FA" ]
PMC12780771
39763143
10.1093/aje/kwaf001
Improving accuracy in the estimation of probable dementia in racially and ethnically diverse groups with penalized regression and transfer learning.
Algorithmic estimations of dementia status are widely used in public health and epidemiologic research, but inadequate algorithm performance across racial/ethnic groups has been a barrier. We present improvements in the accuracy of group-specific "probable dementia" estimation using a transfer learning approach. Transf...
American journal of epidemiology
2026
Am J Epidemiol. 2025 Jan 6;195(1):237–45. doi: 10.1093/aje/kwaf001
CC BY
[ "Journal Article", "Research Support, Non-U.S. Gov't", "Research Support, N.I.H., Extramural" ]
[ "Kim JH", "Glymour MM", "Langa KM", "Leist AK" ]
PMC12789191
41523668
10.1111/eva.70193
Trait Mapping Utilizing a Newly Constructed Genome for Allohexaploid Invasive Eurasian Watermilfoil (Myriophyllum spicatum) Reveals a Non-Target Site QTL Associated With Fluridone Resistance.
Herbicides are a valuable tool in agricultural ecosystems to manage nuisance species. Due to the reliance on herbicides for weed control, herbicide resistance is a growing concern. Herbicides are also used extensively in aquatic and natural systems, but the genetics and evolutionary dynamics of resistance are not as fr...
Evolutionary applications
2026
Evol Appl. 2026 Jan 9;19(1):e70193. doi: 10.1111/eva.70193
CC BY
[ "Journal Article" ]
[ "Hannay D", "Chorak GM", "Harkess A", "Clevenger J", "Cuperus JT", "Hale H", "Aközbek L", "Meharg Z", "Carey SB", "Myers Z", "Queitsch C", "Stamatoyannopoulos A", "Thum RA" ]
PMC12791084
41521270
10.1007/s40820-025-02001-x
Biomimetic Gradient Lubrication Hydrogel Contrived by Self-Reinforced MOFs Nanoparticle Network.
The development of gradient lubrication materials is critical for numerous biomedical applications, particularly in magnifying mechanical properties and service longevity. Herein, we present an innovative approach to fabricate biomimetic gradient lubrication hydrogel through the synergistic integration of three-dimensi...
Nano-micro letters
2026
Nanomicro Lett. 2026 Jan 12;18:150. doi: 10.1007/s40820-025-02001-x
CC BY
[ "Journal Article" ]
[ "Liu D", "Wang Y", "Bai C", "Hu D", "Yang X", "Lu Y", "Wu T", "Zhai F", "Jiang P", "Wang X", "Liu W" ]
PMC12786797
41515695
10.3390/ma19010027
Re-Valorizing Oyster-Shell Waste in Natural Hydraulic Lime-Based Mortars for Brick Substrate Applications: Performance and Durability.
The re-valorisation of oyster-shell waste offers a sustainable pathway for producing eco-efficient construction materials. This study investigates the physical, mechanical, and durability performance of natural hydraulic lime (NHL) mortars incorporating oyster shells (OSs), applied to solid bricks representative of his...
Materials (Basel, Switzerland)
2025
Materials (Basel). 2025 Dec 20;19(1):27. doi: 10.3390/ma19010027
CC BY
[ "Journal Article" ]
[ "Bellei P", "Pereira MFC", "Torres I", "Foray G", "Flores-Colen I" ]
PMC12783835
41345200
10.1038/s41598-025-30440-4
Silver and polystyrene nanoparticles activate oestrogen signalling via cytoplasmic oestrogen receptor.
This study explores the endocrine-disrupting potential of two commonly encountered nanomaterials, nanoplastic and silver nanoparticles (AgNPs). Many environmental pollutants, especially endocrine-disrupting chemicals (EDCs), such as bisphenol, heavy metals, interfere with hormone function, posing a serious risk for pub...
Scientific reports
2025
Sci Rep. 2025 Dec 4;16:948. doi: 10.1038/s41598-025-30440-4
CC BY
[ "Journal Article", "Research Support, Non-U.S. Gov't" ]
[ "Lekki-Porębski SA", "Męczyńska-Wielgosz S", "Kruszewski M", "Grzelak A" ]
PMC12781209
41523969
10.31083/AP49235
Machine Learning Based Identification of Depressive Symptoms Among Students in a Chinese University Using Functional Near-Infrared Spectroscopy.
BACKGROUND: Individuals suffer from depression at a high rate on university campuses and current assessment methods primarily rely on subjective questionnaires. Therefore, there is a pressing need to develop objective measures for the automatic detection of depression. This study aimed to investigate the functional nea...
Alpha psychiatry
2025
Alpha Psychiatry. 2025 Dec 18;26(6):49235. doi: 10.31083/AP49235
CC BY
[ "Journal Article" ]
[ "Wei Y", "Chen Y", "Wang N", "Zheng H", "Zhan Z", "Luo P", "Yan J", "Yang L", "Liu R", "Ji G", "Zheng W", "Meng Y", "Xiong X" ]
PMC12785746
41516056
10.3390/ijms27010177
Phytochemical Evaluation of Terminalia catappa L. Extracts with Antibacterial and Antibiotic Potentiation Activities Against β-Lactam Drug-Resistant Bacteria.
Terminalia catappa L. (Family: Combretaceae) is used globally to treat various diseases, including bacterial infections. Whilst the antibacterial activity of T. catappa has previously been tested against antibiotic-sensitive bacterial strains, the antimicrobial activity against methicillin and β-lactam-resistant pathog...
International journal of molecular sciences
2025
Int J Mol Sci. 2025 Dec 23;27(1):177. doi: 10.3390/ijms27010177
CC BY
[ "Journal Article" ]
[ "Zai MJ", "Cheesman MJ", "Cock IE" ]
PMC12765113
41492538
10.1016/j.mex.2025.103613
From scores to insights: Predicting MT errors using reliable metrics and linguistic typology in slavic languages.
Machine Translation (MT) evaluation plays a crucial role in advancing systems translating into morphologically rich, low-resource languages such as Slovak. Existing automatic evaluation methods typically offer a single quality score, lacking insight into specific error types. A novel linguistically informed methodology...
MethodsX
2025
MethodsX. 2025 Sep 8;15:103613. doi: 10.1016/j.mex.2025.103613
CC BY
[ "Journal Article" ]
[ "Munkova D", "Benkova L", "Munk M", "Benko Ľ", "Hajek P" ]
PMC12756411
41488909
10.3389/fped.2025.1676609
Recurrent calf myositis as revealing manifestation of Crohn disease: a case report.
Crohn's disease (CD) is a chronic inflammatory bowel disease (IBD) that may present in children with extraintestinal manifestations (EIM). Inflammatory myopathies are rarely described in this context. Herein we describe the case of a teenager with recurrent episodes of calf myositis, also known as "Gastrocnemius Myalgi...
Frontiers in pediatrics
2025
Front Pediatr. 2025 Dec 18;13:1676609. doi: 10.3389/fped.2025.1676609
CC BY
[ "Case Reports", "Journal Article" ]
[ "La Rosa A", "Meneghel A", "Giraudo C", "Zucchetta P", "Tirelli F", "Trevisan F", "Calabrese F", "Zulian F" ]
PMC12786666
41515325
10.3390/molecules31010028
Synthesis and Application of a Glucoconjugated Organometallic Rhenium Complex as an IR Imaging Probe for Glycolytic Cancer Cells.
Current tumor diagnostics rely on fluorodeoxyglucose (FDG)-PET imaging, but FDG's short half-life and high cost limit its widespread use. Infrared (IR) probes are emerging as non-radioactive alternatives to conventional tracers for tissue section and other in vitro imaging applications. Because cells and tissues are re...
Molecules (Basel, Switzerland)
2025
Molecules. 2025 Dec 22;31(1):28. doi: 10.3390/molecules31010028
CC BY
[ "Journal Article" ]
[ "Bononi G", "Paltrinieri E", "Fortunato S", "Cicio G", "Di Giovanni N", "Lencioni G", "Funel N", "Giovannetti E", "Granchi C", "Di Bussolo V", "Minutolo F" ]
PMC12719591
41438576
10.7150/jca.121654
Interleukin-17 receptor A drives cancer stem-like properties in colorectal cancer through STAT3 activation.
Cancer stem cells (CSCs) play pivotal roles in tumor relapse, metastasis, and therapy resistance. Interleukin 17 receptor A (IL-17RA) is a key mediator in colorectal cancer (CRC) pathogenesis and progression. Our recent study demonstrated that reduced IL-17RA expression correlates with favorable prognosis in CRC patien...
Journal of Cancer
2026
J Cancer. 2026 Jan 1;17(1):74–85. doi: 10.7150/jca.121654
CC BY
[ "Journal Article" ]
[ "Jiang JK", "Lin CH", "Lin CC", "Lo LC", "Sung PY", "Wen ZY", "Lin CP", "Chang TA", "Yang CY" ]
PMC12758088
41487823
10.7759/cureus.98370
A Hidden Pathway to a Major Concern: The Role of Pyroptosis in Inducing Myocardial Infarction Reperfusion Injury and Emerging Therapeutic Targets.
Myocardial infarction reperfusion injury (MIRI) is a paradoxical phenomenon. Restoration of blood flow to the heart potentially saves our lives, but at the same time, kills other heart cells. This impact on final infarct size counteracts the advantages of revascularization. While oxidative stress and calcium overload h...
Cureus
2025
Cureus. 2025 Dec 3;17(12):e98370. doi: 10.7759/cureus.98370
CC BY
[ "Journal Article", "Review" ]
[ "Mohammed ZA", "Patni MM", "Qassim MM", "Naji NM", "Al Abid IK", "Kharoufeh A", "Agha AA", "Aloti RA" ]
PMC12793864
40960437
10.1016/j.jaccas.2025.105363
Amplitude-Integrated/Continuous Electroencephalography for Early Detection of Low Cardiac Output After Chest Closure in an Infant.
BACKGROUND: Weaning from cardiopulmonary bypass in pediatric cardiac surgery is challenging, especially after prolonged procedures. Delayed chest closure may be necessary in cases of low cardiac output syndrome (LCOS) to support hemodynamic recovery. Although near-infrared spectroscopy is standard for neuromonitoring, ...
JACC. Case reports
2025
JACC Case Rep. 2025 Sep 17;30(32):105363. doi: 10.1016/j.jaccas.2025.105363
CC BY
[ "Case Reports", "Journal Article" ]
[ "Barbaria A", "Capizzi M", "Sperandeo F", "Castelli G", "Isgrò G", "Aloisio T", "Satriano A", "Giamberti A", "Mastrangelo M", "Ranucci M" ]
PMC12798568
41661703
10.1371/journal.pmen.0000072
Burden and predictors of anxiety disorder among HIV patients on ART in Nairobi Kenya.
Anxiety disorders are prevalent among people living with Human Immunodeficiency Virus (HIV) globally, but data on the prevalence and factors associated with this mental illness are limited among HIV patients on antiretroviral therapy (ART) in Kenya. This study determined the prevalence and correlates of anxiety disorde...
PLOS mental health
2024
PLOS Ment Health. 2024 Jul 1;1(2):e0000072. doi: 10.1371/journal.pmen.0000072
CC BY
[ "Journal Article" ]
[ "Gacau KK", "Mugendi G", "Kiragu G", "Ngayo MO", "Omosa G" ]
PMC12790300
41523724
10.7759/cureus.101235
Petersen's Space Hernia: An Uncommon Diagnosis With Potentially Fatal Consequences.
Petersen's space hernias are a rare but potentially life-threatening complication following Roux-en-Y gastric bypass, seen in both bariatric and oncologic contexts. Although evidence is mixed, some studies suggest a higher risk of internal herniation after laparoscopic procedures. A 52-year-old male patient with a prio...
Cureus
2026
Cureus. 2026 Jan 10;18(1):e101235. doi: 10.7759/cureus.101235
CC BY
[ "Case Reports", "Journal Article" ]
[ "Bernardino R", "Santos PD", "Aparício D", "Miranda L" ]
PMC11864876
39107044
10.1146/annurev-pharmtox-022724-100847
Pharma[e]cology: How the Gut Microbiome Contributes to Variations in Drug Response.
Drugs represent our first, and sometimes last, line of defense for many diseases, yet despite decades of research we still do not fully understand why a given drug works in one patient and fails in the next. The human gut microbiome is one of the missing puzzle pieces, due to its ability to parallel and extend host pat...
Annual review of pharmacology and toxicology
2025
Annu Rev Pharmacol Toxicol. Author manuscript; Available in PMC 2026 Jan 1.
CC BY
[ "Journal Article", "Review", "Research Support, N.I.H., Extramural", "Research Support, Non-U.S. Gov't" ]
[ "Trepka KR", "Olson CA", "Upadhyay V", "Zhang C", "Turnbaugh PJ" ]
PMC12789239
41514150
10.1007/s10006-025-01501-9
The socket-shield technique in orthodontics: a method for alveolar ridge preservation.
BACKGROUND: This study was conducted to investigate the clinical efficacy of Socket-Shield Technique on the adult first premolar bone preservation in Orthodontic Extraction Treatment. METHODS: 26 patients who were underwent Orthodontic Extraction Treatment in the First Affiliated Hospital of Guangzhou Medical Universit...
Oral and maxillofacial surgery
2026
Oral Maxillofac Surg. 2026 Jan 10;30(1):16. doi: 10.1007/s10006-025-01501-9
CC BY
[ "Journal Article", "Randomized Controlled Trial" ]
[ "Zhang Y", "Ji Z", "Lin L", "Ye H", "Ji J" ]
PMC12784755
41514797
10.3390/ani16010109
The Fenestras Elisabeth Complex (Nova Structura) in the Parietal Bone of Plecotus auritus: Morphology, Topography, and Functional Significance.
Fenestrations of mammalian skull bones are rare and poorly understood, particularly within the parietal bone. In bats-a group characterised by advanced sensory specialisation and echolocation-superficial modifications of the cranial vault may have functional significance, yet their occurrence and organisation remain in...
Animals : an open access journal from MDPI
2025
Animals (Basel). 2025 Dec 30;16(1):109. doi: 10.3390/ani16010109
CC BY
[ "Journal Article" ]
[ "Kłys G", "Socha P" ]
PMC12771151
41502610
10.1021/acsomega.5c06418
Biomimetic HA-Reinforced PCL/PLA Fibrous Structures via Solution Blow Spinning: Cocoon-Inspired Design for Bone Regeneration.
Bioinspired materials have been studied for applications in various fields, including aerospace and tissue engineering. In this study, biomimetic fibrous structures, inspired by the cocoons of the Rothschildia sp. moths, were produced by solution blow spinning (SBS) using biodegradable polymers such as polycaprolactone...
ACS omega
2025
ACS Omega. 2025 Nov 21;10(48):58555–65. doi: 10.1021/acsomega.5c06418
CC BY
[ "Journal Article" ]
[ "Almeida CL", "Figueiredo LRF", "Melo JDD", "Medeiros ES" ]
PMC12794642
41531823
10.7717/peerj.20548
New insights into lactylation in respiratory diseases: progress and perspectives.
Lactate is conventionally regarded as a metabolic byproduct and generated through diverse pathophysiological pathways. However, a growing body of evidence supports its regulatory roles in energy metabolism and signal transduction, boosting extensive research into lactate-mediated lactylation as a newly discovered post-...
PeerJ
2026
PeerJ. 2026 Jan 9;14:e20548. doi: 10.7717/peerj.20548
CC BY
[ "Journal Article", "Review" ]
[ "Chen L", "Zou Y", "Xu Q", "Zhang J" ]
PMC12770146
41489698
10.1186/s40643-025-00992-4
Application of image analysis combined with regression models to estimate the reduction of Escherichia coli and Salmonella spp. on vegetable surfaces after washing.
Escherichia coli, a bacterium indicating improper hygiene practices during food production, is commonly found in the intestines of humans and animals, while Salmonella spp. are dangerous bacteria that cause typhoid fever and severe diarrhea. These pathogens have been found in fresh vegetables. This study investigated h...
Bioresources and bioprocessing
2026
Bioresour Bioprocess. 2026 Jan 5;13(1):3. doi: 10.1186/s40643-025-00992-4
CC BY
[ "Journal Article" ]
[ "Chengsa-Ard F", "Rojanakorn T", "Hirunsorn P", "Fuangpaiboon N", "Donlao N", "Tanongkankit Y", "Issara U", "Singh J", "Kaur L", "Tian J", "Phungamngoen C" ]
PMC12756435
41487530
10.3389/fphar.2025.1698727
Nonclinical evaluation of HS630, a proposed biosimilar of trastuzumab emtansine: affinity, pharmacokinetics, and immunogenicity.
OBJECTIVE: The aim of this study is to evaluate the similarity of affinity, pharmacokinetics, and immunogenicity shared by HS630 and trastuzumab emtansine (T-DM1). METHODS: In vitro, affinity was tested using a Biacore™ T200 apparatus. In vivo studies were conducted on tumor-bearing mice and cynomolgus monkeys in the c...
Frontiers in pharmacology
2025
Front Pharmacol. 2025 Dec 18;16:1698727. doi: 10.3389/fphar.2025.1698727
CC BY
[ "Journal Article" ]
[ "Jiang H", "Che J" ]
PMC12787294
41515361
10.3390/molecules31010064
Understanding the Role of Base in Catalytic Transfer Hydrogenation: A Comparative Review.
Catalytic transfer hydrogenation (CTH) provides a practical and sustainable approach for reducing unsaturated compounds, serving as an alternative to high-pressure H2 in laboratory and fine chemical contexts. This broad reaction class includes asymmetric transfer hydrogenation (ATH), a key strategy in enantioselective ...
Molecules (Basel, Switzerland)
2025
Molecules. 2025 Dec 24;31(1):64. doi: 10.3390/molecules31010064
CC BY
[ "Journal Article", "Review" ]
[ "Taleb B", "Al Mousawi A", "Ghadban A", "Hijazi I", "Al Ahmar R", "Bechelany M", "Hijazi A" ]
PMC12786475
41515750
10.3390/ma19010084
Effects of SiC Particle Size on SiCp/Al Composite During Vacuum Hot Pressing.
High-performance SiCp/Al composites were fabricated via a vacuum hot-pressing powder metallurgy process. The effects of SiC particle size on the composite microstructures and their thermal and mechanical properties were systematically investigated. The vacuum hot-pressed SiCp/Al composites exhibited a well-bonded inter...
Materials (Basel, Switzerland)
2025
Materials (Basel). 2025 Dec 25;19(1):84. doi: 10.3390/ma19010084
CC BY
[ "Journal Article" ]
[ "Feng R", "Wu H", "Liu H", "Yang Y", "Pei B", "Han J", "Liu Z", "Wu X", "Huang Z" ]
PMC12781744
41501943
10.1186/s44215-025-00234-1
Orthotopic heart transplantation for Fontan failure: experience and treatment strategy-a case report.
BACKGROUND: Orthotopic heart transplantation after the Fontan operation presents technical surgical challenges due to the connection of systemic veins to pulmonary arteries and well-developed systemic-to-pulmonary collateral arteries. The altered anatomy and hemodynamics necessitate extensive vascular reconstruction. W...
General thoracic and cardiovascular surgery cases
2026
Gen Thorac Cardiovasc Surg Cases. 2026 Jan 7;5:2. doi: 10.1186/s44215-025-00234-1
CC BY
[ "Journal Article" ]
[ "Horie S", "Shikata F", "Hirata Y", "Tsuji S", "Moriyama S", "Ando M", "Inuzuka R", "Kato H", "Ono M" ]
PMC12757948
41487894
10.1093/jscr/rjaf1023
Pancreatic necrosis as a rare complication of left hemicolectomy-case report.
A 77-year-old female patient was hospitalized due to acute renal failure, during which a colonoscopy was performed because of constipation. The examination revealed an adenocarcinoma of the sigmoid colon. A left hemicolectomy was performed without intraoperative complications. Three days after surgery, the patient repo...
Journal of surgical case reports
2026
J Surg Case Rep. 2026 Jan 2;2026(1):rjaf1023. doi: 10.1093/jscr/rjaf1023
CC BY
[ "Case Reports", "Journal Article" ]
[ "Mikołaj D", "Grzegorz F", "Tomasz K", "Jacek Ś" ]
PMC12757348
41488648
10.3389/fimmu.2025.1629052
Systemic immune classification related to immune exhaustion evaluates the clinical response of patients with HBV-HCC after transarterial chemoembolization.
Transarterial chemoembolization (TACE) has the potential to activate the immune system and regulate the tumor microenvironment. This study assesses the clinical response of patients with HBV-related hepatocellular carcinoma (HBV-HCC) after TACE treatment based on systemic immune classification (SIC). A total of 80 pati...
Frontiers in immunology
2025
Front Immunol. 2025 Dec 19;16:1629052. doi: 10.3389/fimmu.2025.1629052
CC BY
[ "Journal Article" ]
[ "Yu L", "Liu X", "Hu Y", "Yan H", "Xie Y", "Shang Z", "Liang Y", "Shi W", "Du J", "Jiang Y", "Zhang H", "Yang Z" ]
PMC12769494
41449278
10.1007/s10238-025-01997-1
MAFLD increases CKM syndrome severity: a NHANES-based cross-sectional study.
The cardiovascular-kidney-metabolic (CKM) syndrome is a newly proposed clinical concept that emphasizes the interconnected burden of renal and cardiometabolic dysfunction. However, the impact of metabolic dysfunction-associated fatty liver disease (MAFLD) within the CKM staging framework is still unknown. This cross-se...
Clinical and experimental medicine
2025
Clin Exp Med. 2025 Dec 26;26(1):79. doi: 10.1007/s10238-025-01997-1
CC BY
[ "Journal Article" ]
[ "Mostafa AM", "Fouad Y", "Pan Z", "Alem SA", "AbdAllah M", "Abdelsameea E", "Eslam M" ]
PMC12785303
41515527
10.3390/diagnostics16010032
Observational Management for Patients with Biochemical Recurrence Following Radical Prostatectomy, in the Absence of Detectable Disease on Restaging PSMA PET/CT Imaging.
Background/Objectives: In men with biochemical recurrence (BCR) after a radical prostatectomy (RP), salvage radiotherapy (SRT) is commonly recommended when imaging shows no metastases. The optimal management for patients with negative prostate-specific membrane antigen (PSMA) PET/CT findings at BCR remains uncertain. T...
Diagnostics (Basel, Switzerland)
2025
Diagnostics (Basel). 2025 Dec 22;16(1):32. doi: 10.3390/diagnostics16010032
CC BY
[ "Journal Article" ]
[ "de Bie KCC", "Mellema JJ", "Meijer D", "Teunissen FR", "van Leeuwen PJ", "Oprea-Lager DE", "Donswijk ML", "van den Bergh RCN", "Vis AN" ]
PMC12784544
41514473
10.1186/s13020-025-01273-0
Electroacupuncture ameliorates incisional pain via suppressing IL-33 signaling-related macrophage infiltration and ROS overproduction in incised skin.
BACKGROUND: Postoperative pain develops after surgical operation. Inadequately managed postoperative pain is oftentimes associated with deterioration in life quality and delayed rehabilitation. Clinical studies confirmed analgesic effects of acupuncture on patients with postoperative pain. We hereby explored mechanisms...
Chinese medicine
2026
Chin Med. 2026 Jan 9;21:26. doi: 10.1186/s13020-025-01273-0
CC BY
[ "Journal Article" ]
[ "Xu R", "Zheng K", "Pan Y", "Li P", "Chen M", "Nie H", "Liu B", "Tai Y", "He X", "Du J", "Fang J", "Tian G", "Liu B" ]
PMC12759220
40952151
10.1002/adma.202502427
Non-PFAS-Based Magnetic Polymer Sorbents for Efficient Removal of Perfluorinated Compounds from Landfill Leachate.
Per- and polyfluoroalkyl substances (PFAS) are carcinogenic and environmentally persistent contaminants, necessitating their efficient removal to protect environmental and human health. In this study, a series of fluorinated, non-PFAS-based magnetic polymer sorbents is developed for the selective removal of multiple PF...
Advanced materials (Deerfield Beach, Fla.)
2026
Adv Mater. 2025 Sep 15;38(1):e02427. doi: 10.1002/adma.202502427
CC BY
[ "Journal Article" ]
[ "Tan X", "Yang Z", "Chen Z", "Zhu Y", "Yu C", "Wang Y", "Liu K", "Dewapriya P", "Li X", "Su Z", "Giansiracusa MJ", "Boskovic C", "Wang B", "Thomas KV", "Zhang C" ]
PMC12768045
41497019
10.1097/MS9.0000000000003928
A bibliometric analysis of the top 100 most-cited articles in interventional cardiology: trends, authors, journals, origins, and gender representation.
INTRODUCTION: Bibliometric analysis provides a quantitative and objective method to identify research trends, influential authors, and institutions within a field, guiding both researchers and funding bodies. AIM: To identify and evaluate the top 100 most-cited articles in interventional cardiology, analyzing citation ...
Annals of medicine and surgery (2012)
2026
Ann Med Surg (Lond). 2025 Sep 23;88(1):344–56. doi: 10.1097/MS9.0000000000003928
CC BY
[ "Journal Article", "Review" ]
[ "Abdullah A", "Abdul Qadeer M", "Jamil A", "Nadeem ZA", "Siddique A", "Azhar H", "Sabahat SE", "Kailash SJ", "Hassan Virk HU" ]
PMC12786754
41517630
10.3390/jcm15010381
The Role of Biological Effective Dose in Gamma Knife Radiosurgery: A Systematic Review Across Multiple Indications.
Background: Gamma Knife radiosurgery (GKS) is widely used for the management of intracranial disorders. Emerging evidence suggests that incorporating the biological effective dose (BED) into GKS planning may improve the prediction of treatment efficacy and toxicity. This review aims to evaluate the role of BED in GKS a...
Journal of clinical medicine
2026
J Clin Med. 2026 Jan 5;15(1):381. doi: 10.3390/jcm15010381
CC BY
[ "Journal Article", "Review" ]
[ "Deng H", "Huang X", "Wang Q", "Gao Y", "Wang M", "Wu Y", "Shi X", "Wang M", "Pan W", "Yin S", "Wang W" ]
PMC12767197
40581366
10.1093/jhered/esaf040
A chromosome-level reference genome assembly for Gilbert's skink Plestiodon gilberti.
Advances in genomic studies are revealing that gene flow between species is more frequent than previously understood, although the ways in which hybridization can bias gene flow across species boundaries or the extent to which introgression might be adaptive remain unexplored in most systems. We report on an annotated ...
The Journal of heredity
2026
J Hered. 2025 Jun 23;117(1):115–25. doi: 10.1093/jhered/esaf040
CC BY
[ "Journal Article" ]
[ "Richmond JQ", "Escalona M", "Marimuthu MPA", "Nguyen O", "Sacco S", "Beraut E", "Toffelmier E", "Karin BR", "Cooper RD", "Fisher RN", "Wang IJ", "Shaffer HB" ]
PMC12786622
41517326
10.3390/jcm15010076
Prevalence of Obesity and Overweight Among Children in Aseer Region, Saudi Arabia.
Background: Childhood overweight and obesity represent growing public health challenges globally, driven by complex interactions between demographic, behavioral, and familial factors. This study assessed the prevalence and determinants of overweight and obesity among school-aged children and adolescents attending urban...
Journal of clinical medicine
2025
J Clin Med. 2025 Dec 22;15(1):76. doi: 10.3390/jcm15010076
CC BY
[ "Journal Article" ]
[ "Alqahtani YA", "Shati AA", "Asiri AA", "Dawood SA", "Almaker YA", "AlShahrani AF", "Nasser AA", "Alqahtani SM" ]
PMC12771114
41502820
10.3389/fnut.2025.1652271
Mapping research landscapes: a bibliometric and visual analysis of ketogenic diet interventions in liver health (2013-2024).
OBJECTIVE: Bibliometric and visual analysis in the field of ketogenic diet (KD) on Liver Health from 2013 to 2024. METHODS: We retrieved the articles published between 2013 and 2024 from the Web of Science database and the Scopus database, and conducted the analysis using R software and VOSviewer software. RESULTS: The...
Frontiers in nutrition
2025
Front Nutr. 2025 Dec 23;12:1652271. doi: 10.3389/fnut.2025.1652271
CC BY
[ "Journal Article", "Systematic Review" ]
[ "Wang Y", "Lu Q", "Ma H", "Huang J", "Zhang B", "Qin Y", "Feng Z", "Jin X" ]
PMC12786379
41028968
10.1002/advs.202512467
Toward Practical Li-Ion Cells With Li/Mn-Rich Layered Oxide Cathodes: A Techno-Economic Perspective on Material and Cell Design.
Li/Mn-rich layered oxide (LMR) cathode active materials offer a pathway towards high specific energy and low-cost Li ion batteries (LIBs) due to their high practical specific discharge capacity (>250 mAh g-1) at moderate discharge voltages (≈3.5 V). However, oxygen redox requires electrochemical activation at high cath...
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
2026
Adv Sci (Weinh). 2025 Sep 30;13(2):e12467. doi: 10.1002/advs.202512467
CC BY
[ "Journal Article", "Review" ]
[ "Arifiadi A", "Oster S", "Eum D", "Voigt D", "Kulka A", "Hur H", "Winter M", "Kasnatscheew J" ]
PMC12788765
41538669
10.1590/S0004-2803.24612025-013
EARLY ILEOCECAL RESECTION IN CROHN'S DISEASE: A SYSTEMATIC REVIEW.
BACKGROUND: The approval of new therapies has led to an increasing trend toward the use of various combinations of medications in Crohn's disease (CD) management. However, patients with ileocecal CD may still require surgery in up to 80% of cases. OBJECTIVES: To analyze the literature and synthesize the data qualitativ...
Arquivos de gastroenterologia
2026
Arq Gastroenterol. 2026 Jan 9;62:e25013. doi: 10.1590/S0004-2803.24612025-013
CC BY
[ "Journal Article", "Systematic Review" ]
[ "Todescatto AD", "Quaresma AB", "Kotze PG" ]
PMC12786615
41517621
10.3390/jcm15010369
The Role of Personal Values in the Context of the Relationship Between Perceived Stress and Satisfaction with Life in the Group of Uniformed Personnel Treated in a Mental Health Clinic.
Background/Objectives: Personal values shape appraisal of stress and life satisfaction. We examined the relationship between perceived stress and life satisfaction among uniformed personnel in outpatient mental health care, and the role of a personal values hierarchy in this context. Methods: Cross-sectional study of 1...
Journal of clinical medicine
2026
J Clin Med. 2026 Jan 4;15(1):369. doi: 10.3390/jcm15010369
CC BY
[ "Journal Article" ]
[ "Curyło M", "Zabojszcz M", "Tkaczyk L", "Iwolska J", "Mikos M", "Strzępek Ł", "Czerw A", "Charkiewicz D", "Partyka O", "Pajewska M", "Sygit K", "Sygit M", "Wysocki S", "Gąska I", "Kaczmar E", "Grochans E", "Cybulska AM", "Schneider-Matyka D", "Bandurska E", "Ciećko W", "Drobn...
PMC12787993
41515059
10.3390/plants15010114
Arbuscular Mycorrhizal Fungi Inoculation and Different Phosphorus Fertilizer Levels Modulate Phosphorus Acquisition and Utilization Efficiency of Alfalfa (Medicago sativa L.) in Saline-Alkali Soil.
Phosphorus (P) is a key nutrient limiting crop growth and productivity, particularly in saline-alkali soils with low P availability. Arbuscular mycorrhizal fungi (AMF) have the potential to enhance P uptake in alfalfa (Medicago sativa L.); however, the synergistic effects and underlying biological mechanisms by which A...
Plants (Basel, Switzerland)
2025
Plants (Basel). 2025 Dec 31;15(1):114. doi: 10.3390/plants15010114
CC BY
[ "Journal Article" ]
[ "Zhong S", "Hou P", "Yu M", "Cao W", "Tu X", "Ma X", "Miao F", "Tao Q", "Sun J", "Jia W" ]
PMC12767054
41203584
10.1002/advs.202512325
Quantifying the Single-Cell Morphological Landscape of Cellular Transdifferentiation through Force Field Reconstruction.
Advancements in sequencing technologies have reshaped our understanding of cell behaviors through transcriptomics, but a gap remains in developing quantitative models for multi-omic data, especially for cellular morphology changes. A pivotal challenge is the lack of cell-specific velocity information, crucial for recon...
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
2026
Adv Sci (Weinh). 2025 Nov 7;13(1):e12325. doi: 10.1002/advs.202512325
CC BY
[ "Journal Article" ]
[ "Yu C", "Liu C", "Wang E", "Wang J" ]
PMC12781395
41340103
10.1186/s12883-025-04548-z
Combined training improves functional capacity, fatigue, and quality of life in individuals with multiple sclerosis: a systematic review and meta-analysis.
INTRODUCTION: Multiple Sclerosis (MS) severely affects strength, coordination, gait, and balance, leading to significant challenges for individuals. While exercise is known to benefit MS management, most studies focus on single modalities, leaving a gap in understanding the effects of combined training (CT) interventio...
BMC neurology
2025
BMC Neurol. 2025 Dec 3;26:17. doi: 10.1186/s12883-025-04548-z
CC BY
[ "Journal Article", "Systematic Review", "Meta-Analysis" ]
[ "Kazemi Pakdel F", "Kazemi Pakdel A", "Zarei H", "Brian A" ]
PMC12757973
41487621
10.3389/fpubh.2025.1692668
The impact of basketball on the physical health of Chinese middle school students aged 12-18: a systematic review and meta-analysis.
PURPOSE: This systematic review evaluates the impact of basketball on the physical fitness of Chinese middle school students, providing evidence-based support for research on how basketball enhances the physical health of Chinese students aged 12-18. METHOD: Using CNKI, WanFang, WeiPu, PubMed, Web of Science, Embase, a...
Frontiers in public health
2025
Front Public Health. 2025 Dec 19;13:1692668. doi: 10.3389/fpubh.2025.1692668
CC BY
[ "Journal Article", "Systematic Review", "Meta-Analysis" ]
[ "Richen S", "Xiaolong X", "Weilong L", "Xiaoning S", "Hengtong W" ]
PMC12788287
41516703
10.3390/s26010268
Deep Learning Wavefront Sensing from Object Scene for Directed Energy HEL Systems.
Atmospheric turbulence significantly degrades the performance of High Energy Laser (HEL) systems by distorting the laser wavefront as it propagates through the atmosphere. Conventional correction techniques rely on Adaptive Optics (AO), which preserve beam quality at the object. However, AO systems require wavefront se...
Sensors (Basel, Switzerland)
2026
Sensors (Basel). 2026 Jan 1;26(1):268. doi: 10.3390/s26010268
CC BY
[ "Journal Article" ]
[ "Herrera L", "Messina N", "Agrawal BN" ]
PMC12776489
41510293
10.21203/rs.3.rs-8290863/v1
Altered Perivascular Diffusivity in Glioblastoma:Integrating DTI-ALPS Index with Radio-Pathomicand Histopathologic Correlates.
PURPOSE: Glioblastoma is an aggressive primary brain tumor that often exhibits perivascular invasion. This behavior may directly interfere with glymphatic flow, hindering perivascular drainage routes. This study aims to assess glymphatic dysfunction in glioblastoma by evaluating the DTI-ALPS index, an MRI-based surroga...
Research square
2025
Res Sq. 2025 Dec 22:rs.3.rs-8290863. Preprint. [Version 1] doi: 10.21203/rs.3.rs-8290863/v1
CC BY
[ "Journal Article", "Preprint" ]
[ "Nath B", "Bobholz SA", "Kim DC", "Lowman AK", "Duenweg SR", "Winiarz A", "Chao B", "Kyereme F", "Barrett M", "Reecher HM", "Connelly J", "S Mrachek EK", "Jacobsohn J", "Krucoff MO", "T E", "Mohit A", "Daniel D", "Banerjee A", "LaViolette PS" ]
PMC12787592
41515242
10.3390/nu18010125
Assessment of Post-Discharge Growth Pattern After Initial Growth Faltering and Its Association with the Neurodevelopment Status in Preterm Infants: A Cohort Study.
BACKGROUND: Preterm infants are at risk of growth faltering at term age. Our primary objective is to assess post-discharge growth patterns in these infants and investigate the association between growth faltering and neurodevelopment. METHODS: We divided the sample into two groups according to growth during the initial...
Nutrients
2025
Nutrients. 2025 Dec 30;18(1):125. doi: 10.3390/nu18010125
CC BY
[ "Journal Article" ]
[ "Witte Castro A", "Gonzalez CD", "Segura SA", "Saenz de Pipaon M" ]
PMC12767155
41497793
10.2478/joeb-2025-0018
Changes in bioelectrical and non-bioelectrical variables associated with overweight after a weight-loss program based on intestinal microbiota modulation.
OBJECTIVE: To assess changes in clinical and bioelectrical impedance analysis (BIA) variables associated with overweight, after a 6-day weight-loss protocol based on intestinal microbiota modulation. METHODS: A group of 12 young overweight women (OG) were randomly assigned to either a control subgroup (COG, n=6) or an ...
Journal of electrical bioimpedance
2025
J Electr Bioimpedance. 2025 Dec 17;16(1):135–45. doi: 10.2478/joeb-2025-0018
CC BY
[ "Journal Article" ]
[ "Tapasco-Tapasco LO", "Gonzalez-Correa CA", "Gomez-Buitrago PA" ]
PMC12754272
41480629
10.1002/hsr2.71706
Knowledge, Attitudes, Practices, and Misconceptions Regarding Vitamins in Blood Metabolism and Anemia Among University Students: A One Center Cross-Sectional Study in Ghana.
BACKGROUND: In Sub-Saharan Africa, anemia is a significant public health issue, affecting individuals of all ages. While prevention efforts focus on infants, children, and pregnant women, adolescents are overlooked often, leading to ongoing challenges. Despite its prevalence, there is a paucity of research on anemia in...
Health science reports
2026
Health Sci Rep. 2025 Dec 31;9(1):e71706. doi: 10.1002/hsr2.71706
CC BY
[ "Journal Article" ]
[ "Donkor DM", "Owusu G", "Essuon-Sepah V", "Asamoah O", "Anokye I", "Sah AK", "Apalebilah S", "Adu P", "Boachie J" ]
PMC12789354
41522537
10.1007/s12288-025-02064-1
Safe and Efficient Extracorporeal Photopheresis in Patients with Pre-Procedure Hematocrit below 26.
BACKGROUND: Extracorporeal photopheresis (ECP) is widely used for graft-versus-host disease (GVHD), but manufacturer recommendations suggest maintaining a pre-procedure hematocrit (Hct) above 27%. This study evaluates the safety and efficacy of ECP performed at lower Hct levels. METHODS: We retrospectively analyzed 13 ...
Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion
2026
Indian J Hematol Blood Transfus. 2025 May 31;42(1):255–8. doi: 10.1007/s12288-025-02064-1
CC BY
[ "Journal Article" ]
[ "Pavlovich A", "Matthews F", "Akgun Y" ]
PMC12765082
41492292
10.1016/j.onehlt.2025.101177
A one health approach to prioritizing emerging zoonotic diseases (EZDs) in northern Vietnam.
BACKGROUND: Vietnam, with its significant agricultural sector, large livestock population, rich biodiversity and close human-animal interactions, is highly vulnerable to zoonotic disease transmission. To better address this threat, representatives from the human, animal, and environmental health sectors in Vietnam work...
One health (Amsterdam, Netherlands)
2025
One Health. 2025 Aug 21;21:101177. doi: 10.1016/j.onehlt.2025.101177
CC BY
[ "Journal Article" ]
[ "Nam LH", "Nguyen-Tien T", "Lindahl JF", "Dang-Xuan S", "Duc PP", "Unger F", "Vuong BN", "Tung DD", "Nguyen-Viet H", "Lee HS" ]
PMC12783791
41501025
10.1038/s41467-025-67500-2
Boosting superconductivity in ultrathin YBa2Cu3O7-δ films via nanofaceted substrates.
In cuprate high-temperature superconductors the doping level is fixed during synthesis, hence the charge carrier density per CuO2 plane cannot be easily tuned by conventional gating, unlike in 2D materials. Strain engineering has recently emerged as a powerful tuning knob for manipulating the properties of cuprates, in...
Nature communications
2026
Nat Commun. 2026 Jan 7;17:285. doi: 10.1038/s41467-025-67500-2
CC BY
[ "Journal Article" ]
[ "Wahlberg E", "Arpaia R", "Chakraborty D", "Kalaboukhov A", "Vignolles D", "Proust C", "Black-Schaffer AM", "Bauch T", "Seibold G", "Lombardi F" ]
PMC12756761
41487182
10.1021/acsomega.5c09524
Comparison of Different Encapsulation Techniques in Exosomes Obtained from Goat and Bovine Milk.
Exosomes are the smallest extracellular vesicles and can transport several molecules between cells. Mammalian milk is a significant source of exosomes. The aim of this study was to isolate exosomes from goat milk (GM) and cow milk (CM) to compare their properties and their capacities for loading with bioactive compound...
ACS omega
2025
ACS Omega. 2025 Dec 16;10(51):63202–12. doi: 10.1021/acsomega.5c09524
CC BY
[ "Journal Article" ]
[ "de Oliveira MCTG", "Costa HPS", "Teixeira D", "Sousa DOB", "Gadelha CRF", "Guedes MIF", "van Tilburg MF" ]
PMC12757864
41488698
10.1093/ofid/ofaf771
Monocyte Activation in People With HIV and Tuberculosis Coinfection and Effect of Tuberculosis Preventive Therapy: An Analysis of the ACTG A5279/BRIEF TB Trial.
BACKGROUND: Monocyte activation contributes to the pathogenesis of inflammation-driven comorbidities in people with HIV (PWH). We investigated the impact of tuberculin skin test (TST)/interferon-γ release assay (IGRA) status and tuberculosis preventive therapy (TPT) on monocyte activation in PWH. METHODS: We analyzed p...
Open forum infectious diseases
2026
Open Forum Infect Dis. 2025 Dec 15;13(1):ofaf771. doi: 10.1093/ofid/ofaf771
CC BY
[ "Journal Article" ]
[ "Huaman MA", "Feria MG", "Kendall MA", "McKhann A", "Supparatpinyo K", "Chougnet CA", "Du X", "Sawe FK", "Erlandson KM", "Utay NS", "Lederman MM", "Swindells S", "Gupta A", "Chaisson RE", "Fichtenbaum CJ" ]
PMC12796827
41536315
10.1093/nsr/nwaf536
Unsupervised classification of non-Hermitian topological phases under symmetries.
The integration of machine learning into fundamental science has opened new avenues for addressing long-standing challenges rooted in mathematical limitations. For instance, while topological invariants are essential for characterizing topological phases of matter, no single invariant is universally applicable. This li...
National science review
2026
Natl Sci Rev. 2025 Nov 27;13(1):nwaf536. doi: 10.1093/nsr/nwaf536
CC BY
[ "Journal Article" ]
[ "Long Y", "Xue H", "Zhang B" ]
PMC12754778
41474265
10.1093/nar/gkaf1429
A mitotic bookmark coordinates transcription and replication in Drosophila embryos.
Collisions between advancing replication forks and elongating transcripts pose a universal threat. During the rapid nuclear division cycles in early Drosophila embryos, coordinating transcription and replication is critical to reduce the risk of collisions. In each cycle, replication begins immediately after mitosis, w...
Nucleic acids research
2025
Nucleic Acids Res. 2025 Dec 31;53(22):gkaf1429. doi: 10.1093/nar/gkaf1429
CC BY
[ "Journal Article", "Research Support, N.I.H., Extramural" ]
[ "Cho CY", "O'Farrell PH" ]
PMC12757341
41488464
10.3389/fcvm.2025.1689234
Differential prognostic value of high-sensitivity troponin T based on renal function status: insights from 14,208 ACS patients undergoing PCI.
BACKGROUND AND OBJECTIVES: High-sensitivity troponin T (hsTnT) is a standard biomarker for myocardial injury detection, but its prognostic value may differ by renal function status. This study evaluated how renal function modifies the prognostic significance of hsTnT in ACS patients undergoing PCI. METHODS: This study ...
Frontiers in cardiovascular medicine
2025
Front Cardiovasc Med. 2025 Dec 19;12:1689234. doi: 10.3389/fcvm.2025.1689234
CC BY
[ "Journal Article" ]
[ "Na K", "Yang X", "Qiu M", "Zhang X", "Li Y", "Han Y" ]
PMC12786389
41222285
10.1107/S205252062500914X
OD (order-disorder) interpretation and diffuse scattering analysis of an organic polytype with allotwin character: a detailed how-to.
2,3-Dihydroxy-1,3,4-trimethyl-6-oxo-1,4-cyclohexadiene-1-carboxylic acid crystallizes in an order-disorder (OD) structure with a high stacking fault probability. The diffraction pattern features diffuse scattering and broad peaks, which can be attributed to fragments of two polytypes of a maximum degree of order (MDO)....
Acta crystallographica Section B, Structural science, crystal engineering and materials
2025
Acta Crystallogr B Struct Sci Cryst Eng Mater. 2025 Nov 11;81(Pt 6):550–64. doi: 10.1107/S205252062500914X
CC BY
[ "Journal Article" ]
[ "Fröschl D", "Kratena N", "Stöger B", "Virovets A", "Wolflehner T" ]
PMC12777311
41331623
10.1186/s13293-025-00792-7
Sex-dimorphic reprogramming of fetal mouse brain development by maternal estradiol excess.
BACKGROUND: Gestational environmental perturbations can induce sex-specific developmental programming, increasing offspring susceptibility to chronic diseases. While prenatal high estradiol (HE) exposure has been associated with male-biased neurodevelopmental disorders, the underlying mechanisms remain poorly understoo...
Biology of sex differences
2025
Biol Sex Differ. 2025 Dec 2;17:1. doi: 10.1186/s13293-025-00792-7
CC BY
[ "Journal Article", "Research Support, Non-U.S. Gov't" ]
[ "Wang H", "Wei Z", "Zhang Y", "Chen X", "Jin L", "Zhou C" ]
PMC12785853
41511355
10.3390/cells15010072
Inflammatory Mechanisms in Acute Coronary Syndromes: From Pathophysiology to Therapeutic Targets.
Inflammation plays a pivotal role in the pathogenesis of acute coronary syndromes (ACS), contributing to plaque instability, thrombosis, and myocardial injury. This review aims to comprehensively examine the inflammatory mechanisms underlying ACS and evaluate current and emerging anti-inflammatory therapeutic strategie...
Cells
2025
Cells. 2025 Dec 31;15(1):72. doi: 10.3390/cells15010072
CC BY
[ "Journal Article", "Review" ]
[ "Brie DM", "Mornoș C", "Adam O", "Tîrziu A", "Popescu R", "Brie AD" ]
PMC12766179
40147625
10.1016/j.jare.2025.03.025
Prognostic value of tryptophan catabolism-base scores in acute myocardial infarction patients.
AIMS: Tryptophan catabolism is implicated in the progression of cardiovascular disease. We sought to investigate the prognostic value of tryptophan catabolism-related features in patients with acute myocardial infarction (AMI). METHODS AND RESULTS: A prospective cohort of 4071 patients (mean age: 60.7 years; 69.1 % men...
Journal of advanced research
2026
J Adv Res. 2025 Mar 25;79:563–70. doi: 10.1016/j.jare.2025.03.025
CC BY
[ "Journal Article", "Research Support, Non-U.S. Gov't" ]
[ "Wang Y", "Wu P", "Chen Z", "Li Z", "Wang Y", "Yan M", "Zhang Y", "Wang S", "Fang S", "Yu B" ]
PMC12785761
41522794
10.5334/aogh.5020
Pathways to Clinical Training Opportunities for International Medical Students and IMGs: The California Experience.
Many global health initiatives involve partnerships between US academic institutions and low- or middle-income country (LMIC) institutions, but substantial inequities exist in short-term clinical education exchange opportunities for LMIC institutions. US medical students and physicians frequently participate in clinica...
Annals of global health
2026
Ann Glob Health. 2026 Jan 8;92(1):3. doi: 10.5334/aogh.5020
CC BY
[ "Journal Article" ]
[ "Akey M", "Groves B", "Hudspeth JC", "Rabin TL", "Cortez S", "Silvers R", "Novotny J", "Negussie F", "Orozco P", "Le P", "Sawhney R", "Raykar N", "Arteaga M", "Davis Rodriguez JA", "Curran M", "Byekwaso S", "Saab F", "Bandolin NS", "Lipnick MS" ]
End of preview. Expand in Data Studio

PMC open-access abstracts (10,000) with MedCPT embeddings

Research data, not for clinical use. These abstracts and embeddings support a retrieval demo and must not be used to inform medical decisions.

Titles and abstracts of 10,000 articles released in PubMed Central from 2026-01-01 to 2026-01-14 under CC0 or CC BY licences, with embeddings from NCBI's MedCPT article encoder, computed in JAX and verified against Hugging Face Transformers. Built with biomed-retrieval-jax, which searches them in its biomed-search command and its demo.

Files

  • documents.jsonl: one article per line, with pmcid, pmid, doi, title, abstract (structured abstracts' sections labelled as "LABEL: text"), journal, year, citation, license ("CC0" or "CC BY"), publication_types and authors ("Surname Initials", in PubMed's order).
  • embeddings.npy: a float32 array of shape (10,000, 768); row i is the embedding of line i of documents.jsonl, from ncbi/MedCPT-Article-Encoder at revision d05a736da4bb84ee4057b7f7999485be6ed85465, on (title, abstract) pairs, with [CLS] pooling, truncated at 512 tokens.
  • manifest.json: how the corpus and embeddings were built: the query, dates and seed, every exclusion, the exact model revisions and the commits.

How the articles were selected

Candidates were the 26,144 articles released in PubMed Central from 2026-01-01 to 2026-01-14 with a CC0 or CC BY licence and no embargo, found with NCBI's E-utilities. In a seeded random order, each article's licence and retraction status were checked in its metadata on PMC's Cloud Service, and its title, abstract, authors and publication types were taken from PubMed, until 10,000 articles passed. An article was kept only if it is indexed in PubMed, has an abstract, and is not retracted, a retraction notice, an erratum or an expression of concern. Of the articles examined, these were excluded: 4,528 not indexed in PubMed (no PMID); 364 with no abstract; 158 of publication type Published Erratum; 69 of publication type Retraction Notice; 5 retracted articles; 4 of publication type Expression of Concern. In a sample of 145 of the articles not indexed in PubMed, 136 came from one journal's supplement of meeting abstracts.

Licences and attribution

Each article keeps its own licence, given in its license field: 9,963 are licensed CC BY and 37 CC0. Each record includes the article's authors, title, journal citation and DOI; if you reuse the texts, please credit their authors. The texts are taken from the articles' PubMed records. The code that built this dataset is licensed Apache-2.0. MedCPT is released by NCBI under a public-domain notice; please cite Jin et al., MedCPT, Bioinformatics 39(11), 2023.

Use

import json

import numpy as np
from huggingface_hub import snapshot_download

path = snapshot_download("xquantize/biomed-retrieval-jax-pmc-10k", repo_type="dataset")
documents = [json.loads(line) for line in open(f"{path}/documents.jsonl")]
embeddings = np.load(f"{path}/embeddings.npy")

To search, embed a query with ncbi/MedCPT-Query-Encoder (revision d83a36cc6b8e3a5c5e9d9d6ba156808c1643dcbc; at most 64 tokens, [CLS] pooling) and score the documents by dot product, as biomed-search does.

Limitations

  • Two weeks of publications: many questions have no directly relevant article here.
  • Only articles indexed in PubMed; retractions as known when the corpus was built.
  • 166 articles are preprints, which have not been peer-reviewed: their publication_types include "Preprint".
  • Embeddings are of the (title, abstract) pair truncated at 512 tokens; the texts are complete.
  • The largest journals are Cureus (598 articles) and PloS one (335).
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