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Graph Transformer Geometric Learning of Brain Networks Using Multimodal MR Images for Brain Age Estimation.
Accurate brain age prediction with lightweight deep neural networks.
Cardiac MRI in patients with COVID-19 infection.
Brain age is considered as an important biomarker for detecting aging-related diseases such as Alzheimer's Disease (AD). Magnetic resonance imaging (MRI) have been widely investigated with deep neural networks for brain age estimation. However, most existing methods cannot make full use of multimodal MRIs due to the di...
Deep learning has huge potential for accurate disease prediction with neuroimaging data, but the prediction performance is often limited by training-dataset size and computing memory requirements. To address this, we propose a deep convolutional neural network model, Simple Fully Convolutional Network (SFCN), for accur...
COVID-19 infection is a systemic disease with various cardiovascular symptoms and complications. Cardiac MRI with late gadolinium enhancement is the modality of choice for the assessment of myocardial involvement. T1 and T2 mapping can increase diagnostic accuracy and improve further management. Our study aimed to eval...
Graph Transformer Geometric Learning of Brain Networks Using Multimodal MR Images for Brain Age Estimation. Brain age is considered as an important biomarker for detecting aging-related diseases such as Alzheimer's Disease (AD). Magnetic resonance imaging (MRI) have been widely investigated with deep neural networks fo...
Accurate brain age prediction with lightweight deep neural networks. Deep learning has huge potential for accurate disease prediction with neuroimaging data, but the prediction performance is often limited by training-dataset size and computing memory requirements. To address this, we propose a deep convolutional neura...
Cardiac MRI in patients with COVID-19 infection. COVID-19 infection is a systemic disease with various cardiovascular symptoms and complications. Cardiac MRI with late gadolinium enhancement is the modality of choice for the assessment of myocardial involvement. T1 and T2 mapping can increase diagnostic accuracy and im...
33839631
30616875
33451816
Innumerable hemorrhagic brain metastases from a neuroendocrine tumor grade-1 with prolonged natural history.
Surgical treatment of an asymptomatic giant supratentorial cavernous hemangioma. Case report.
Large-Volume Hyperthermia for Safe and Cost-Effective Targeted Drug Delivery Using a Clinical Ultrasound-Guided Focused Ultrasound Device.
Neuroendocrine tumors (NET) are rare tumors with a low incidence of brain metastasis, especially in grade 1 NET. The most common source of brain metastasis is the lung. We present an unusual case of NET grade 1 with multiple hemorrhagic brain metastases.</AbstractText A 46-year-old woman, who initially presented with a...
A case is reported of a 19-year old patient with a supratentorial giant cavernous malformation (GCM). This was an incidental finding in the context of acute head trauma. Brain computed tomography (CT) scan and magnetic resonance imaging (MRI) revealed a giant supratentorial right mass. Surgical excision was performed, ...
Lyso-thermosensitive liposomes (LTSLs) are specifically designed to release chemotherapy agents under conditions of mild hyperthermia. Preclinical studies have indicated that magnetic resonance (MR)-guided focused ultrasound (FUS) systems can generate well-controlled volumetric hyperthermia using real-time thermometry....
Innumerable hemorrhagic brain metastases from a neuroendocrine tumor grade-1 with prolonged natural history. Neuroendocrine tumors (NET) are rare tumors with a low incidence of brain metastasis, especially in grade 1 NET. The most common source of brain metastasis is the lung. We present an unusual case of NET grade 1 ...
Surgical treatment of an asymptomatic giant supratentorial cavernous hemangioma. Case report. A case is reported of a 19-year old patient with a supratentorial giant cavernous malformation (GCM). This was an incidental finding in the context of acute head trauma. Brain computed tomography (CT) scan and magnetic resonan...
Large-Volume Hyperthermia for Safe and Cost-Effective Targeted Drug Delivery Using a Clinical Ultrasound-Guided Focused Ultrasound Device. Lyso-thermosensitive liposomes (LTSLs) are specifically designed to release chemotherapy agents under conditions of mild hyperthermia. Preclinical studies have indicated that magnet...
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Feasibility study of 2D Dixon-Magnetic Resonance Fingerprinting (MRF) of breast cancer.
Repeatability of MR fingerprinting in normal cervix and utility in cervical carcinoma.
Comparison of response properties of the electrically stimulated auditory nerve reported in human listeners and in animal models.
Application of MRF to evaluate the feasibility of 2D Dixon blurring-corrected MRF (2DDb-cMRF) to differentiate breast cancer (BC) from normal fibroglandular tissue (FGT).</AbstractText Prospective study on 14 patients with unilateral BC on 1.5&#xa0;T system/axial T2w-TSE sequence, 2DDb-cMRF, B1 map, dynamic contrast-en...
Magnetic resonance fingerprinting (MRF) is a fast-imaging acquisition technique that generates quantitative and co-registered parametric maps. The aim of this feasibility study was to evaluate the agreement between MRF and phantom reference values, scan-rescan repeatability of MRF in normal cervix, and its ability to d...
Cochlear implants (CIs) provide acoustic information to implanted patients by electrically stimulating nearby auditory nerve fibers (ANFs) which then transmit the information to higher-level neural structures for further processing and interpretation. Computational models that simulate ANF responses to CI stimuli enabl...
Feasibility study of 2D Dixon-Magnetic Resonance Fingerprinting (MRF) of breast cancer. Application of MRF to evaluate the feasibility of 2D Dixon blurring-corrected MRF (2DDb-cMRF) to differentiate breast cancer (BC) from normal fibroglandular tissue (FGT).</AbstractText Prospective study on 14 patients with unilatera...
Repeatability of MR fingerprinting in normal cervix and utility in cervical carcinoma. Magnetic resonance fingerprinting (MRF) is a fast-imaging acquisition technique that generates quantitative and co-registered parametric maps. The aim of this feasibility study was to evaluate the agreement between MRF and phantom re...
Comparison of response properties of the electrically stimulated auditory nerve reported in human listeners and in animal models. Cochlear implants (CIs) provide acoustic information to implanted patients by electrically stimulating nearby auditory nerve fibers (ANFs) which then transmit the information to higher-level...
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Assessment of myocardial injuries in ischaemic and non-ischaemic cardiomyopathies using magnetic resonance T1-rho mapping.
Assessment of acute kidney injury with T1 mapping MRI following solid organ transplantation.
Post-stroke Chinese pure alexia: linguistic features and neuropsychological profiles.
To identify clinical correlates of myocardial T1&#x3c1; and to examine how myocardial T1&#x3c1; values change under various clinical scenarios.</AbstractText A total of 66 patients (26% female, median age 57 years [Q1-Q3, 44-65 years]) with known structural heart disease and 44 controls (50% female, median age 47 years...
To evaluate T1 mapping as a non-invasive, functional MRI biomarker in patients shortly after solid organ transplantation to detect acute postsurgical kidney damage and to correlate T1 times with renal function.</AbstractText 101 patients within 2&#xa0;weeks after solid organ transplantation (49 kidney transplantation, ...
Very few cases of Chinese pure alexia have been reported to date. We aim to summarize the linguistic features and neuropsychological profiles of Chinese pure alexia through a case series study.</AbstractText 11 consecutive patients with post-stroke Chinese pure alexia and 11 healthy controls were included. The Aphasia ...
Assessment of myocardial injuries in ischaemic and non-ischaemic cardiomyopathies using magnetic resonance T1-rho mapping. To identify clinical correlates of myocardial T1&#x3c1; and to examine how myocardial T1&#x3c1; values change under various clinical scenarios.</AbstractText A total of 66 patients (26% female, med...
Assessment of acute kidney injury with T1 mapping MRI following solid organ transplantation. To evaluate T1 mapping as a non-invasive, functional MRI biomarker in patients shortly after solid organ transplantation to detect acute postsurgical kidney damage and to correlate T1 times with renal function.</AbstractText 10...
Post-stroke Chinese pure alexia: linguistic features and neuropsychological profiles. Very few cases of Chinese pure alexia have been reported to date. We aim to summarize the linguistic features and neuropsychological profiles of Chinese pure alexia through a case series study.</AbstractText 11 consecutive patients wi...
30470988
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31203463
Homophone Advantage in Sentence Acceptability Judgment: An Experiment with Japanese Kanji Words and Articulatory Suppression Technique.
The effects of aging on conflict detection.
Skeletal Muscle Wasting and Its Relationship With Osteoarthritis: a Mini-Review of Mechanisms and Current Interventions.
The purpose of this study was to examine the role and nature of phonology in silent reading of Japanese sentences. An experiment was conducted using a Japanese sentence acceptability judgment task. One important finding was that participants more rapidly rejected homophonic sentences in which one two-kanji compound wor...
Several cognitive changes characterize normal aging; one change regards inhibitory processing and includes both conflict monitoring and response suppression. We attempted to segregate these two aspects within a Go/No-go task, investigating three age categories. Accuracy, response times and event-related potentials (ERP...
Osteoarthritis (OA) is a subset of joint disorders resulting in degeneration of synovial joints. This leads to pain, disability and loss of independence. Knee and hip OA are extremely prevalent, and their occurrence increases with ageing. Similarly, loss of muscle mass and function, sarcopenia, occurs during ageing.</A...
Homophone Advantage in Sentence Acceptability Judgment: An Experiment with Japanese Kanji Words and Articulatory Suppression Technique. The purpose of this study was to examine the role and nature of phonology in silent reading of Japanese sentences. An experiment was conducted using a Japanese sentence acceptability j...
The effects of aging on conflict detection. Several cognitive changes characterize normal aging; one change regards inhibitory processing and includes both conflict monitoring and response suppression. We attempted to segregate these two aspects within a Go/No-go task, investigating three age categories. Accuracy, resp...
Skeletal Muscle Wasting and Its Relationship With Osteoarthritis: a Mini-Review of Mechanisms and Current Interventions. Osteoarthritis (OA) is a subset of joint disorders resulting in degeneration of synovial joints. This leads to pain, disability and loss of independence. Knee and hip OA are extremely prevalent, and ...
35851275
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Meta-analytic evidence that mindfulness training alters resting state default mode network connectivity.
Test-retest reliabilities of resting-state FMRI measurements in human brain functional connectomics: a systems neuroscience perspective.
Upper Gastrointestinal Tract IrAEs: A Case Report About Sintilimab-Induced Acute Erosive Hemorrhagic Gastritis.
This meta-analysis sought to expand upon neurobiological models of mindfulness through investigation of inherent brain network connectivity outcomes, indexed via resting state functional connectivity (rsFC). We conducted a systematic review and meta-analysis of rsFC as an outcome of mindfulness training (MT) relative t...
Resting-state functional magnetic resonance imaging (RFMRI) enables researchers to monitor fluctuations in the spontaneous brain activities of thousands of regions in the human brain simultaneously, representing a popular tool for macro-scale functional connectomics to characterize normal brain function, mind-brain ass...
Immune checkpoint inhibitors (ICIs) have now become the standard therapy for malignancies like non-small cell lung cancer and classical Hodgkin's lymphoma. ICIs are associated with unique immune-related adverse events (irAEs) caused by dysregulated immune activation. Treatment of lower gastrointestinal (GI) tract irAEs...
Meta-analytic evidence that mindfulness training alters resting state default mode network connectivity. This meta-analysis sought to expand upon neurobiological models of mindfulness through investigation of inherent brain network connectivity outcomes, indexed via resting state functional connectivity (rsFC). We cond...
Test-retest reliabilities of resting-state FMRI measurements in human brain functional connectomics: a systems neuroscience perspective. Resting-state functional magnetic resonance imaging (RFMRI) enables researchers to monitor fluctuations in the spontaneous brain activities of thousands of regions in the human brain ...
Upper Gastrointestinal Tract IrAEs: A Case Report About Sintilimab-Induced Acute Erosive Hemorrhagic Gastritis. Immune checkpoint inhibitors (ICIs) have now become the standard therapy for malignancies like non-small cell lung cancer and classical Hodgkin's lymphoma. ICIs are associated with unique immune-related adver...
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23288627
28523468
Devising a Method to Study if Wernicke's Aphasia Patients are Aware That They Do Not Comprehend Language or Speak It Understandably.
Defining language networks from resting-state fMRI for surgical planning--a feasibility study.
Development of a novel radiotherapy motion phantom using a stepper motor driver circuit and evaluation using optical surface scanning.
Wernicke's Aphasia (WA) is characterized by an individual speaking fluent gibberish without the ability to understand anything that is said to them or anything they attempt to read. It is caused by damage to the left posterior temporoparietal cortex, also known as Wernicke's area. An additional intriguing symptom of WA...
Presurgical language mapping for patients with lesions close to language areas is critical to neurosurgical decision-making for preservation of language function. As a clinical noninvasive imaging technique, functional MRI (fMRI) is used to identify language areas by measuring blood-oxygen-level dependent (BOLD) signal...
Recent developments in radiotherapy have focused on the management of patient motion during treatment. Studies have shown that significant gains in treatment quality can be made by 'gating' certain treatments, simultaneously keeping target coverage, and increasing separation to nearby organs at risk (OAR). Motion phant...
Devising a Method to Study if Wernicke's Aphasia Patients are Aware That They Do Not Comprehend Language or Speak It Understandably. Wernicke's Aphasia (WA) is characterized by an individual speaking fluent gibberish without the ability to understand anything that is said to them or anything they attempt to read. It is...
Defining language networks from resting-state fMRI for surgical planning--a feasibility study. Presurgical language mapping for patients with lesions close to language areas is critical to neurosurgical decision-making for preservation of language function. As a clinical noninvasive imaging technique, functional MRI (f...
Development of a novel radiotherapy motion phantom using a stepper motor driver circuit and evaluation using optical surface scanning. Recent developments in radiotherapy have focused on the management of patient motion during treatment. Studies have shown that significant gains in treatment quality can be made by 'gat...
38845969
35304554
39253727
Methodology exploration and reproducibility evaluation of TAI and TSI for quantitative ultrasound assessment of hepatic steatosis.
T1 reduction rate with Gd-EOB-DTPA determines liver function on both 1.5 T and 3 T MRI.
Potential roles of voltage-gated ion channel disruption in Tuberous Sclerosis Complex.
New quantitative ultrasound techniques can be used to quantify hepatic steatosis, including tissue attenuation imaging (TAI), tissue scatter -distribution imaging (TSI), and the hepatorenal index (HRI). However, the measurement norms and the effects of fasting on these measurements remain unclear. The present study per...
Magnetic resonance T1 mapping before and after Gd-EOB-DTPA administration allows quantification of the T1 reduction rate as a non-invasive surrogate marker of liver function. A major limitation of T1 relaxation time measurement is its dependency on MRI field strengths. Since T1 reduction rate is calculated as the relat...
Tuberous Sclerosis Complex (TSC) is a lynchpin disorder, as it results in overactive mammalian target of rapamycin (mTOR) signaling, which has been implicated in a multitude of disease states. TSC is an autosomal dominant disease where 90% of affected individuals develop epilepsy. Epilepsy results from aberrant neurona...
Methodology exploration and reproducibility evaluation of TAI and TSI for quantitative ultrasound assessment of hepatic steatosis. New quantitative ultrasound techniques can be used to quantify hepatic steatosis, including tissue attenuation imaging (TAI), tissue scatter -distribution imaging (TSI), and the hepatorenal...
T1 reduction rate with Gd-EOB-DTPA determines liver function on both 1.5 T and 3 T MRI. Magnetic resonance T1 mapping before and after Gd-EOB-DTPA administration allows quantification of the T1 reduction rate as a non-invasive surrogate marker of liver function. A major limitation of T1 relaxation time measurement is i...
Potential roles of voltage-gated ion channel disruption in Tuberous Sclerosis Complex. Tuberous Sclerosis Complex (TSC) is a lynchpin disorder, as it results in overactive mammalian target of rapamycin (mTOR) signaling, which has been implicated in a multitude of disease states. TSC is an autosomal dominant disease whe...
32765286
35075810
31847650
Acute Low Dose of Trazodone Recovers Glutamate Release Efficiency and mGlu2/3 Autoreceptor Impairments in the Spinal Cord of Rats Suffering From Chronic Sciatic Ligation.
Serotonin receptors in epilepsy: Novel treatment targets?
Spinal cord stimulation modulates complexity of neural activities in patients with disorders of consciousness.
We investigated whether chronic sciatic ligation modifies the glutamate release in spinal cord nerve endings (synaptosomes) as well as the expression and the function of presynaptic release-regulating mGlu2/3 autoreceptors and 5-HT<sub
Despite the availability of over 30 antiseizure medications (ASMs), there is no "one size fits it all," so there is a continuing search for novel ASMs. There are divergent data demonstrating that modulation of distinct serotonin (5-hydroxytryptamine, 5-HT) receptors subtypes could be beneficial in the treatment of epil...
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Acute Low Dose of Trazodone Recovers Glutamate Release Efficiency and mGlu2/3 Autoreceptor Impairments in the Spinal Cord of Rats Suffering From Chronic Sciatic Ligation. We investigated whether chronic sciatic ligation modifies the glutamate release in spinal cord nerve endings (synaptosomes) as well as the expression...
Serotonin receptors in epilepsy: Novel treatment targets? Despite the availability of over 30 antiseizure medications (ASMs), there is no "one size fits it all," so there is a continuing search for novel ASMs. There are divergent data demonstrating that modulation of distinct serotonin (5-hydroxytryptamine, 5-HT) recep...
Spinal cord stimulation modulates complexity of neural activities in patients with disorders of consciousness. <b
40210657
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Children engage neural reward structures for creative musical improvisation.
The role of the hippocampus in navigation is memory.
Copper homeostasis and neurodegenerative diseases.
Children spontaneously engage in creative behaviors. However, little is known about the biological underpinnings of creativity in children. We identified neural substrates associated with musical improvisation in children aged 9-11. Participants played a non-ferromagnetic piano keyboard in a functional magnetic resonan...
There is considerable research on the neurobiological mechanisms within the hippocampal system that support spatial navigation. In this article I review the literature on navigational strategies in humans and animals, observations on hippocampal function in navigation, and studies of hippocampal neural activity in anim...
Copper, one of the most prolific transition metals in the body, is required for normal brain physiological activity and allows various functions to work normally through its range of concentrations. Copper homeostasis is meticulously maintained through a complex network of copper-dependent proteins, including copper tr...
Children engage neural reward structures for creative musical improvisation. Children spontaneously engage in creative behaviors. However, little is known about the biological underpinnings of creativity in children. We identified neural substrates associated with musical improvisation in children aged 9-11. Participan...
The role of the hippocampus in navigation is memory. There is considerable research on the neurobiological mechanisms within the hippocampal system that support spatial navigation. In this article I review the literature on navigational strategies in humans and animals, observations on hippocampal function in navigatio...
Copper homeostasis and neurodegenerative diseases. Copper, one of the most prolific transition metals in the body, is required for normal brain physiological activity and allows various functions to work normally through its range of concentrations. Copper homeostasis is meticulously maintained through a complex networ...
32525133
30287460
32576849
A Novel Metallic Artifact Reduction Technique When Using a Computed Tomography-Guided Percutaneous Metallic Antenna to Ablate Malignant Pulmonary Nodules: A Qualitative and Quantitative Assessment.
Subtraction CTA: An Alternative Imaging Option for the Follow-Up of Flow-Diverter-Treated Aneurysms?
The Contribution of Oculomotor Functions to Rates of Visual Information Processing in Younger and Older Adults.
BACKGROUND Metallic microwave ablation (MWA) antenna-related artifacts are usually created in conventional CT images, and these artifacts can influence the effect of ablation. The aim of this study was to evaluate a new type of metal artifact reduction (MAR+) technique in CT-guided MWA for lung cancer. MATERIAL AND MET...
This was a pilot study to explore the diagnostic accuracy and safety of subtraction CTA combined with a single-energy metal artifact reduction algorithm (SEMAR) compared to DSA for the evaluation of intracranial aneurysm occlusion after flow diverter treatment.</AbstractText We included patients treated with a flow div...
Oculomotor functions are established surrogate measures of visual attention shifting and rate of information processing, however, the temporal characteristics of saccades and fixations have seldom been compared in healthy educated samples of younger and older adults. Thus, the current study aimed to compare duration of...
A Novel Metallic Artifact Reduction Technique When Using a Computed Tomography-Guided Percutaneous Metallic Antenna to Ablate Malignant Pulmonary Nodules: A Qualitative and Quantitative Assessment. BACKGROUND Metallic microwave ablation (MWA) antenna-related artifacts are usually created in conventional CT images, and ...
Subtraction CTA: An Alternative Imaging Option for the Follow-Up of Flow-Diverter-Treated Aneurysms? This was a pilot study to explore the diagnostic accuracy and safety of subtraction CTA combined with a single-energy metal artifact reduction algorithm (SEMAR) compared to DSA for the evaluation of intracranial aneurys...
The Contribution of Oculomotor Functions to Rates of Visual Information Processing in Younger and Older Adults. Oculomotor functions are established surrogate measures of visual attention shifting and rate of information processing, however, the temporal characteristics of saccades and fixations have seldom been compar...
26257617
22928717
25689583
Conditioned place preference successfully established in typically developing children.
Annual Research Review: Resilient functioning in maltreated children--past, present, and future perspectives.
Orally administrated Lactobacillus pentosus var. plantarum C29 ameliorates age-dependent colitis by inhibiting the nuclear factor-kappa B signaling pathway via the regulation of lipopolysaccharide production by gut microbiota.
Affective processing, known to influence attention, motivation, and emotional regulation is poorly understood in young children, especially for those with neurodevelopmental disorders characterized by language impairments. Here we faithfully adapt a well-established animal paradigm used for affective processing, condit...
Through a process of probabilistic epigenesis, child maltreatment progressively contributes to compromised adaptation on a variety of developmental domains central to successful adjustment. These developmental failures pose significant risk for the emergence of psychopathology across the life course. In addition to the...
To evaluate the anti-inflammaging effect of lactic acid bacteria (LAB) on age-dependent inflammation, we first screened and selected a tumor necrosis factor (TNF)-&#x3b1; and reactive oxygen species (ROS)-inhibitory LAB, Lactobacillus pentosus var. plantarum C29, among the LABs isolated from fermented vegetables using ...
Conditioned place preference successfully established in typically developing children. Affective processing, known to influence attention, motivation, and emotional regulation is poorly understood in young children, especially for those with neurodevelopmental disorders characterized by language impairments. Here we f...
Annual Research Review: Resilient functioning in maltreated children--past, present, and future perspectives. Through a process of probabilistic epigenesis, child maltreatment progressively contributes to compromised adaptation on a variety of developmental domains central to successful adjustment. These developmental ...
Orally administrated Lactobacillus pentosus var. plantarum C29 ameliorates age-dependent colitis by inhibiting the nuclear factor-kappa B signaling pathway via the regulation of lipopolysaccharide production by gut microbiota. To evaluate the anti-inflammaging effect of lactic acid bacteria (LAB) on age-dependent infla...
22373615
37192344
22356744
Perspective: Upcoming paradigm shifts for psychiatry in clinical care, research, and education.
Optogenetic stimulation of the superior colliculus suppresses genetic absence seizures.
Growth, photosynthesis and antioxidant responses of endophyte infected and non-infected rice under lead stress conditions.
Psychiatry is facing a crisis fueled by a fragmented and inefficient system of care delivery and a disconnection between the state of research and the state of psychiatry education and practice. Many factors contribute to the current state of psychiatric care. Psychiatry is a shortage specialty, and this will become wo...
While anti-seizure medications are effective for many patients, nearly one-third of individuals have seizures that are refractory to pharmacotherapy. Prior studies using evoked preclinical seizure models have shown that pharmacological activation or excitatory optogenetic stimulation of the deep and intermediate layers...
An endophytic fungus was tested in rice (Oryza sativa L.) exposed to four levels of lead (Pb) stress (0, 50, 100 and 200 &#x3bc;M) to assess effects on plant growth, photosynthesis and antioxidant enzyme activity. Under Pb stress conditions, endophyte-infected seedlings had greater shoot length but lower root length co...
Perspective: Upcoming paradigm shifts for psychiatry in clinical care, research, and education. Psychiatry is facing a crisis fueled by a fragmented and inefficient system of care delivery and a disconnection between the state of research and the state of psychiatry education and practice. Many factors contribute to th...
Optogenetic stimulation of the superior colliculus suppresses genetic absence seizures. While anti-seizure medications are effective for many patients, nearly one-third of individuals have seizures that are refractory to pharmacotherapy. Prior studies using evoked preclinical seizure models have shown that pharmacologi...
Growth, photosynthesis and antioxidant responses of endophyte infected and non-infected rice under lead stress conditions. An endophytic fungus was tested in rice (Oryza sativa L.) exposed to four levels of lead (Pb) stress (0, 50, 100 and 200 &#x3bc;M) to assess effects on plant growth, photosynthesis and antioxidant ...
31210734
28119135
31649200
Dissecting Static and Dynamic Functional Connectivity: Example From the Autism Spectrum.
Relative latency and temporal variability of hemodynamic responses at the human primary visual cortex.
Broadly protective human antibodies that target the active site of influenza virus neuraminidase.
The ability to measure the intrinsic functional architecture of the brain has grown exponentially over the last 2 decades. Measures of intrinsic connectivity within the brain, typically measured using resting-state functional magnetic resonance imaging (MRI), have evolved from primarily "static" approaches, to include ...
The blood-oxygen-level-dependent (BOLD) functional MRI (fMRI) signal is a robust surrogate for local neuronal activity. However, it has been shown to vary substantially across subjects, brain regions, and repetitive measurements. This variability represents a limit to the precision of the BOLD response and the ability ...
Better vaccines against influenza virus are urgently needed to provide broader protection against diverse strains, subtypes, and types. Such efforts are assisted by the identification of novel broadly neutralizing epitopes targeted by protective antibodies. Influenza vaccine development has largely focused on the hemag...
Dissecting Static and Dynamic Functional Connectivity: Example From the Autism Spectrum. The ability to measure the intrinsic functional architecture of the brain has grown exponentially over the last 2 decades. Measures of intrinsic connectivity within the brain, typically measured using resting-state functional magne...
Relative latency and temporal variability of hemodynamic responses at the human primary visual cortex. The blood-oxygen-level-dependent (BOLD) functional MRI (fMRI) signal is a robust surrogate for local neuronal activity. However, it has been shown to vary substantially across subjects, brain regions, and repetitive m...
Broadly protective human antibodies that target the active site of influenza virus neuraminidase. Better vaccines against influenza virus are urgently needed to provide broader protection against diverse strains, subtypes, and types. Such efforts are assisted by the identification of novel broadly neutralizing epitopes...
37451091
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36437188
Higher education level as a protective factor against executive dysfunction in patients with epilepsy in Mataram, Indonesia.
Loneliness and Risk of Dementia.
The chicken and egg problem of grid cells and place cells.
Since the concept of cognitive reserve is applicable in epilepsy-associated cognitive impairment, the role of cognitive reserve components as a protective factor against epilepsy-associated executive dysfunction needs further investigation. This study aimed at investigating the association between cognitive reserve com...
The present study tests whether loneliness is associated with risk of dementia in the largest sample to date and further examines whether the association is independent of social isolation, a related but independent component of social integration, and whether it varies by demographic factors and genetic vulnerability....
Place cells and grid cells are major building blocks of the hippocampal cognitive map. The prominent forward model postulates that grid-cell modules are generated by a continuous attractor network; that a velocity signal evoked during locomotion moves entorhinal activity bumps; and that place-cell activity constitutes ...
Higher education level as a protective factor against executive dysfunction in patients with epilepsy in Mataram, Indonesia. Since the concept of cognitive reserve is applicable in epilepsy-associated cognitive impairment, the role of cognitive reserve components as a protective factor against epilepsy-associated execu...
Loneliness and Risk of Dementia. The present study tests whether loneliness is associated with risk of dementia in the largest sample to date and further examines whether the association is independent of social isolation, a related but independent component of social integration, and whether it varies by demographic f...
The chicken and egg problem of grid cells and place cells. Place cells and grid cells are major building blocks of the hippocampal cognitive map. The prominent forward model postulates that grid-cell modules are generated by a continuous attractor network; that a velocity signal evoked during locomotion moves entorhina...
19529979
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19416835
Evaluation of utility of asymmetric index for count-based oxygen extraction fraction on dual-tracer autoradiographic method for chronic unilateral brain infarction.
Highly constrained backprojection for time-resolved MRI.
Transgenic multivitamin corn through biofortification of endosperm with three vitamins representing three distinct metabolic pathways.
For diagnosing patients with ischemic cerebrovascular disease, non-invasive count-based method with (15)O(2) and H (2) (15) O positron-emission tomography (PET) data is widely used to measure asymmetric increases in oxygen extraction fraction (OEF). For shortening study time, we have proposed dual-tracer autoradiograph...
Recent work in k-t BLAST and undersampled projection angiography has emphasized the value of using training data sets obtained during the acquisition of a series of images. These techniques have used iterative algorithms guided by the training set information to reconstruct time frames sampled at well below the Nyquist...
Vitamin deficiency affects up to 50% of the world's population, disproportionately impacting on developing countries where populations endure monotonous, cereal-rich diets. Transgenic plants offer an effective way to increase the vitamin content of staple crops, but thus far it has only been possible to enhance individ...
Evaluation of utility of asymmetric index for count-based oxygen extraction fraction on dual-tracer autoradiographic method for chronic unilateral brain infarction. For diagnosing patients with ischemic cerebrovascular disease, non-invasive count-based method with (15)O(2) and H (2) (15) O positron-emission tomography ...
Highly constrained backprojection for time-resolved MRI. Recent work in k-t BLAST and undersampled projection angiography has emphasized the value of using training data sets obtained during the acquisition of a series of images. These techniques have used iterative algorithms guided by the training set information to ...
Transgenic multivitamin corn through biofortification of endosperm with three vitamins representing three distinct metabolic pathways. Vitamin deficiency affects up to 50% of the world's population, disproportionately impacting on developing countries where populations endure monotonous, cereal-rich diets. Transgenic p...
40381124
35682902
40209050
Limettin and PD98059 Mitigated Alzheimer's Disease Like Pathology Induced by Streptozotocin in Mouse Model: Role of p-ERK1/2/p-GSK-3β/p-CREB/BDNF Pathway.
Physical Activity Rewires the Human Brain against Neurodegeneration.
What do patients with traumatic brachial plexus injuries need for social and emotional support? A qualitative analysis.
Sporadic Alzheimer's disease (SAD) represents one of the major memory deficits that is characterized by tau hyperphosphorylation and amyloid beta (A&#x3b2;) deposition in the brain. Both are considered AD hallmarks which are mediated through neuroinflammation, oxidative stress, and cholinergic circuit interruption. Thi...
Physical activity may offset cognitive decline and dementia, but the molecular mechanisms by which it promotes neuroprotection remain elusive. In the absence of disease-modifying therapies, understanding the molecular effects of physical activity in the brain may be useful for identifying novel targets for disease mana...
Patients with adult traumatic brachial plexus injury (BPI) face numerous challenges, both directly and indirectly related to their physical disability, during their adjustment to life after injury. Our goal was to identify domains of care in which a patient navigator could improve delivery of care for BPI patients as t...
Limettin and PD98059 Mitigated Alzheimer's Disease Like Pathology Induced by Streptozotocin in Mouse Model: Role of p-ERK1/2/p-GSK-3β/p-CREB/BDNF Pathway. Sporadic Alzheimer's disease (SAD) represents one of the major memory deficits that is characterized by tau hyperphosphorylation and amyloid beta (A&#x3b2;) depositi...
Physical Activity Rewires the Human Brain against Neurodegeneration. Physical activity may offset cognitive decline and dementia, but the molecular mechanisms by which it promotes neuroprotection remain elusive. In the absence of disease-modifying therapies, understanding the molecular effects of physical activity in t...
What do patients with traumatic brachial plexus injuries need for social and emotional support? A qualitative analysis. Patients with adult traumatic brachial plexus injury (BPI) face numerous challenges, both directly and indirectly related to their physical disability, during their adjustment to life after injury. Ou...
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36801466
39755228
Renal Epithelioid Angiomyolipoma: Prognostic Implications of Targeted Immunohistochemical and Molecular Markers in Conjunction with Clinicopathologic Features.
Determinants of Progression and Mortality in Lymphangioleiomyomatosis.
Explaining neuronal membrane potentials: The Goldman equation vs. Lee's TELC hypothesis.
Epithelioid angiomyolipoma (eAML) is an uncommon subtype of angiomyolipoma, a subset of which can demonstrate malignant behavior. While some studies have proposed histopathologic features predictive of aggressive behavior in eAML, there is limited data on the use of immunohistochemistry (IHC) and/or next-generation seq...
Lymphangioleiomyomatosis is a progressive diffuse cystic lung disease with approximately 85%&#xa0;survival at 10 years. The determinants of disease progression and mortality after the introduction of sirolimus therapy and vascular endothelial growth factor D (VEGF-D) as a biomarker have not been well defined.</Abstract...
In two recent papers (Curr Trends Neurol 17: 83-98, 2023; J Neurophysiol 124: 1029-1044, 2020), James Lee has argued that his Transmembrane Electrostatically-Localized Cations (TELC) hypothesis offers a model of neuron transmembrane potentials that is superior to Hodgkin-Huxley classic cable theory and the Goldman-Hodg...
Renal Epithelioid Angiomyolipoma: Prognostic Implications of Targeted Immunohistochemical and Molecular Markers in Conjunction with Clinicopathologic Features. Epithelioid angiomyolipoma (eAML) is an uncommon subtype of angiomyolipoma, a subset of which can demonstrate malignant behavior. While some studies have propos...
Determinants of Progression and Mortality in Lymphangioleiomyomatosis. Lymphangioleiomyomatosis is a progressive diffuse cystic lung disease with approximately 85%&#xa0;survival at 10 years. The determinants of disease progression and mortality after the introduction of sirolimus therapy and vascular endothelial growth...
Explaining neuronal membrane potentials: The Goldman equation vs. Lee's TELC hypothesis. In two recent papers (Curr Trends Neurol 17: 83-98, 2023; J Neurophysiol 124: 1029-1044, 2020), James Lee has argued that his Transmembrane Electrostatically-Localized Cations (TELC) hypothesis offers a model of neuron transmembran...
39212585
33837273
39060234
Pharmacological Treatment of Tourette Disorder in Children.
Whole-exome sequencing identifies genes associated with Tourette's disorder in multiplex families.
Functional architecture of intracellular oscillations in hippocampal dendrites.
<i
Tourette's Disorder (TD) is a neurodevelopmental disorder (NDD) that affects about 0.7% of the population and is one of the most heritable NDDs. Nevertheless, because of its polygenic nature and genetic heterogeneity, the genetic etiology of TD is not well understood. In this study, we combined the segregation informat...
Fast electrical signaling in dendrites is central to neural computations that support adaptive behaviors. Conventional techniques lack temporal and spatial resolution and the ability to track underlying membrane potential dynamics present across the complex three-dimensional dendritic arbor in vivo. Here, we perform fa...
Pharmacological Treatment of Tourette Disorder in Children. <i
Whole-exome sequencing identifies genes associated with Tourette's disorder in multiplex families. Tourette's Disorder (TD) is a neurodevelopmental disorder (NDD) that affects about 0.7% of the population and is one of the most heritable NDDs. Nevertheless, because of its polygenic nature and genetic heterogeneity, the...
Functional architecture of intracellular oscillations in hippocampal dendrites. Fast electrical signaling in dendrites is central to neural computations that support adaptive behaviors. Conventional techniques lack temporal and spatial resolution and the ability to track underlying membrane potential dynamics present a...
40662180
11699120
40394205
The emotional and motivational costs of poorly delivered academic feedback.
The emotional dog and its rational tail: a social intuitionist approach to moral judgment.
Attention-enhanced StrongSORT for robust vehicle tracking in complex environments.
This study uses psychological reactance theory and self-determination theory to explore whether disrespectful or disorganized feedback affects student motivation and classroom engagement.</AbstractText A sample of 148 undergraduates read one of four vignettes describing professor feedback that varied by tone (respectfu...
Research on moral judgment has been dominated by rationalist models, in which moral judgment is thought to be caused by moral reasoning. The author gives 4 reasons for considering the hypothesis that moral reasoning does not cause moral judgment; rather, moral reasoning is usually a post hoc construction, generated aft...
While multi-object tracking is critical for autonomous driving systems, traditional algorithms exhibit three fundamental limitations in complex scenarios: (1) blurred feature representation under occlusion and re-identification scenarios causing identity switches, (2) insufficient sensitivity to scale-variant targets d...
The emotional and motivational costs of poorly delivered academic feedback. This study uses psychological reactance theory and self-determination theory to explore whether disrespectful or disorganized feedback affects student motivation and classroom engagement.</AbstractText A sample of 148 undergraduates read one of...
The emotional dog and its rational tail: a social intuitionist approach to moral judgment. Research on moral judgment has been dominated by rationalist models, in which moral judgment is thought to be caused by moral reasoning. The author gives 4 reasons for considering the hypothesis that moral reasoning does not caus...
Attention-enhanced StrongSORT for robust vehicle tracking in complex environments. While multi-object tracking is critical for autonomous driving systems, traditional algorithms exhibit three fundamental limitations in complex scenarios: (1) blurred feature representation under occlusion and re-identification scenarios...
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Jerjes/neuro-specter2-triplets

Triplet dataset for fine-tuning SPECTER2 on neuroscience.

Version date: 2025-08-12

Schema

Columns:

  • anchor_id, positive_id, negative_id
  • anchor_title, positive_title, negative_title
  • anchor_abstract, positive_abstract, negative_abstract
  • anchor_text, positive_text, negative_text (title + abstract)

Split: train

Load

from datasets import load_dataset
triplets = load_dataset("Jerjes/neuro-specter2-triplets", split="train")
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