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scenario_id
string
crp_t0
int64
crp_t1
int64
crp_t2
int64
il6_proxy_t0
int64
il6_proxy_t1
int64
il6_proxy_t2
int64
temp_t0
float64
temp_t1
float64
temp_t2
float64
wbc_t0
float64
wbc_t1
float64
wbc_t2
float64
immune_regulation_proxy
float64
organ_stress_proxy
float64
treatment_delay
int64
lab_noise
float64
chart_noise
float64
label
int64
IM001
48
52
55
18
20
21
37.8
37.9
38
11.8
12
12.1
0.74
0.32
1
0.31
0.4
0
IM002
50
68
95
20
34
58
37.9
38.4
39
12
14.5
17.2
0.36
0.68
4
0.33
0.42
1
IM003
42
45
47
16
17
18
37.6
37.7
37.8
10.8
11
11.1
0.8
0.28
1
0.28
0.36
0
IM004
46
64
92
18
32
55
37.8
38.3
38.9
11.6
14
16.8
0.34
0.7
4
0.35
0.43
1
IM005
52
54
56
21
22
23
38
38.1
38.1
12.3
12.4
12.5
0.72
0.35
1
0.3
0.38
0
IM006
55
76
108
23
40
66
38.1
38.6
39.2
12.8
15.4
18
0.33
0.73
4
0.37
0.44
1
IM007
40
42
44
15
16
17
37.5
37.6
37.6
10.5
10.7
10.8
0.82
0.26
1
0.27
0.35
0
IM008
49
70
98
19
35
60
37.9
38.5
39.1
11.9
14.8
17.5
0.35
0.69
3
0.34
0.41
1
IM009
47
50
53
18
19
20
37.7
37.8
37.9
11.4
11.6
11.8
0.76
0.31
1
0.29
0.37
0
IM010
53
74
104
22
38
64
38
38.6
39.2
12.4
15.2
17.9
0.34
0.72
4
0.36
0.42
1
IM011
43
46
48
16
17
18
37.6
37.7
37.8
10.9
11.1
11.2
0.79
0.29
1
0.28
0.36
0
IM012
58
80
112
24
42
70
38.2
38.8
39.4
13
15.8
18.6
0.32
0.75
4
0.37
0.44
1
IM013
51
54
56
20
21
22
38
38
38.1
12.1
12.3
12.4
0.73
0.34
1
0.3
0.38
0
IM014
48
67
96
19
34
59
37.8
38.4
39
11.8
14.6
17.3
0.35
0.69
3
0.34
0.41
1
IM015
41
43
45
15
16
17
37.5
37.6
37.7
10.6
10.8
10.9
0.83
0.27
1
0.27
0.35
0
IM016
48
52
55
18
20
21
37.8
37.9
38
11.8
12
12.1
0.74
0.32
1
0.31
0.4
0
IM017
48
52
55
18
26
42
37.8
38.1
38.5
11.8
13.4
15.3
0.42
0.58
3
0.31
0.4
1
IM018
42
45
47
16
17
18
37.6
37.7
37.8
10.8
11
11.1
0.8
0.28
1
0.28
0.36
0
IM019
42
45
47
16
25
40
37.6
38
38.4
10.8
13
15
0.43
0.57
4
0.28
0.36
1
IM020
52
54
56
21
22
23
38
38.1
38.1
12.3
12.4
12.5
0.72
0.35
1
0.3
0.38
0
IM021
55
76
108
23
40
66
38.1
38.6
39.2
12.8
15.4
18
0.33
0.73
4
0.37
0.44
1
IM022
40
42
44
15
16
17
37.5
37.6
37.6
10.5
10.7
10.8
0.82
0.26
1
0.27
0.35
0
IM023
49
70
98
19
35
60
37.9
38.5
39.1
11.9
14.8
17.5
0.35
0.69
3
0.34
0.41
1
IM024
47
50
53
18
19
20
37.7
37.8
37.9
11.4
11.6
11.8
0.76
0.31
1
0.29
0.37
0
IM025
53
74
104
22
38
64
38
38.6
39.2
12.4
15.2
17.9
0.34
0.72
4
0.36
0.42
1
IM026
43
46
48
16
17
18
37.6
37.7
37.8
10.9
11.1
11.2
0.79
0.29
1
0.28
0.36
0
IM027
58
80
112
24
42
70
38.2
38.8
39.4
13
15.8
18.6
0.32
0.75
4
0.37
0.44
1
IM028
51
54
56
20
21
22
38
38
38.1
12.1
12.3
12.4
0.73
0.34
1
0.3
0.38
0
IM029
48
67
96
19
34
59
37.8
38.4
39
11.8
14.6
17.3
0.35
0.69
3
0.34
0.41
1
IM030
41
43
45
15
16
17
37.5
37.6
37.7
10.6
10.8
10.9
0.83
0.27
1
0.27
0.35
0

clinical-immune-dysregulation-cascade-v0.1

What this dataset does

This dataset evaluates whether models can detect immune dysregulation before overt systemic deterioration.

Each row represents a short inflammatory trajectory across three time points.

The task is to classify whether the immune response remains regulated or is moving toward inflammatory cascade instability.

Core stability idea

Immune instability does not depend on one inflammatory marker alone.

A patient may show elevated markers but remain stable if regulation and treatment timing remain adequate.

Conversely, moderate inflammatory escalation can become unstable when cytokine activity, temperature trend, leukocyte response, organ stress, and delayed treatment reinforce each other.

The dataset tests interaction reasoning across:

  • CRP trajectory
  • IL-6 proxy trajectory
  • temperature trajectory
  • WBC trajectory
  • immune regulation proxy
  • organ stress proxy
  • treatment delay

Prediction target

label = 1 → immune dysregulation cascade risk
label = 0 → regulated or stable inflammatory trajectory

Row structure

Each row includes:

  • CRP trajectory
  • IL-6 proxy trajectory
  • temperature trajectory
  • WBC trajectory
  • immune regulation proxy
  • organ stress proxy
  • treatment delay

Decoy variables:

  • lab_noise
  • chart_noise

These variables appear meaningful but do not determine the label alone.

Evaluation

Predictions must use: scenario_id,prediction IM101,0 IM102,1

Run:

python scorer.py --predictions predictions.csv --truth data/test.csv --output metrics.json

Metrics returned:

  • accuracy
  • precision
  • recall
  • f1
  • confusion matrix
  • dataset integrity diagnostics

Structural Note

This dataset reflects latent stability geometry through observable proxies.

The generator and latent rule structure are not included.

This dataset is part of the Clarus Stability Reasoning Benchmark.

Production Deployment

This dataset is intended as a compact benchmark for immune-regulation and inflammatory-cascade reasoning.

It is not a clinical decision tool.

Enterprise & Research Collaboration

This dataset supports research into:

  • immune dysregulation detection
  • inflammatory cascade dynamics
  • trajectory-based reasoning
  • latent stability geometry
  • cross-domain instability benchmarks

License

MIT

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