| --- |
| license: mit |
| tags: |
| - alphafold |
| - clarus |
| - biology |
| - structure |
| - evaluation |
| - safety |
| --- |
| |
| AlphaFold Misinterpretation Classifier (AMC) v0.1 |
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| Purpose |
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| Help models spot when AlphaFold outputs are used to make claims that go beyond their scope. |
| Teach restraint. |
| Promote correct boundaries around structural interpretation. |
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| Columns |
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| - claim |
| - misinterpretation_type |
| - reason_hint |
| - action |
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| misinterpretation_type examples |
| |
| - function_from_structure: assuming activity from fold |
| - binding_assertion: assuming ligand interaction |
| - metric_confusion: misreading confidence or aligned error |
| - state_fixation: treating one conformation as the only state |
| - taxonomy_jump: treating confidence as family evidence |
| |
| action |
| |
| - refuse: decline and point out the jump |
| - request_context: ask for missing conditions |
| - answer_with_correction: correct logic without overreach |
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| Use |
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| - evaluation on biomedical hallucination |
| - model alignment training around biological scope limits |
| - developer sanity checks for RAG systems using AlphaFold output |
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| Boundaries |
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| No lab instructions. |
| No sequence design. |
| No optimization paths. |
| All statements focus on conceptual fit, not engineering. |
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