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Add new SentenceTransformer model

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@@ -0,0 +1,928 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ ---
2
+ tags:
3
+ - sentence-transformers
4
+ - sentence-similarity
5
+ - feature-extraction
6
+ - dense
7
+ - generated_from_trainer
8
+ - dataset_size:17319
9
+ - loss:MultipleNegativesRankingLoss
10
+ base_model: intfloat/multilingual-e5-large
11
+ widget:
12
+ - source_sentence: 'query: The unexpected repercussions of COVID-19 vaccine policy:
13
+ why requirements, certificates and limitations could do more damage than benefit
14
+ | BMJ Global Health'
15
+ sentences:
16
+ - 'passage: title: SARS-CoV-2 infects and replicates in cells of the human endocrine
17
+ and exocrine pancreas abstract: Infection-related diabetes can arise as a result
18
+ of virus-associated β-cell destruction.
19
+
20
+ Clinical data suggest that the severe acute respiratory syndrome coronavirus 2
21
+ (SARS-CoV-2), causing the coronavirus disease 2019 (COVID-19), impairs glucose
22
+ homoeostasis, but experimental evidence that SARS-CoV-2 can infect pancreatic
23
+ tissue has been lacking.
24
+
25
+ In the present study, we show that SARS-CoV-2 infects cells of the human exocrine
26
+ and endocrine pancreas ex vivo and in vivo.
27
+
28
+ We demonstrate that human β-cells express viral entry proteins, and SARS-CoV-2
29
+ infects and replicates in cultured human islets.
30
+
31
+ Infection is associated with morphological, transcriptional and functional changes,
32
+ including reduced numbers of insulin-secretory granules in β-cells and impaired
33
+ glucose-stimulated insulin secretion.
34
+
35
+ In COVID-19 full-body postmortem examinations, we detected SARS-CoV-2 nucleocapsid
36
+ protein in pancreatic exocrine cells, and in cells that stain positive for the
37
+ β-cell marker NKX6.
38
+
39
+ 1 and are in close proximity to the islets of Langerhans in all four patients
40
+ investigated.
41
+
42
+ Our data identify the human pancreas as a target of SARS-CoV-2 infection and suggest
43
+ that β-cell infection could contribute to the metabolic dysregulation observed
44
+ in patients with COVID-19.
45
+
46
+ SARS-CoV-2 is shown to infect and replicate in human pancreatic tissue, including
47
+ in β-cells, which is associated with morphological, transcriptomic and functional
48
+ changes.'
49
+ - 'passage: title: A SARS-like cluster of circulating bat coronaviruses shows potential
50
+ for human emergence abstract: The emergence of severe acute respiratory syndrome
51
+ coronavirus (SARS-CoV) and Middle East respiratory syndrome (MERS)-CoV underscores
52
+ the threat of cross-species transmission events leading to outbreaks in humans.
53
+
54
+ Here we examine the disease potential of a SARS-like virus, SHC014-CoV, which
55
+ is currently circulating in Chinese horseshoe bat populations.
56
+
57
+ Using the SARS-CoV reverse genetics system, we generated and characterized a chimeric
58
+ virus expressing the spike of bat coronavirus SHC014 in a mouse-adapted SARS-CoV
59
+ backbone.
60
+
61
+ The results indicate that group 2b viruses encoding the SHC014 spike in a wild-type
62
+ backbone can efficiently use multiple orthologs of the SARS receptor human angiotensin
63
+ converting enzyme II (ACE2), replicate efficiently in primary human airway cells
64
+ and achieve in vitro titers equivalent to epidemic strains of SARS-CoV.
65
+
66
+ Additionally, in vivo experiments demonstrate replication of the chimeric virus
67
+ in mouse lung with notable pathogenesis.
68
+
69
+ Evaluation of available SARS-based immune-therapeutic and prophylactic modalities
70
+ revealed poor efficacy; both monoclonal antibody and vaccine approaches failed
71
+ to neutralize and protect from infection with CoVs using the novel spike protein.
72
+
73
+ On the basis of these findings, we synthetically re-derived an infectious full-length
74
+ SHC014 recombinant virus and demonstrate robust viral replication both in vitro
75
+ and in vivo.
76
+
77
+ Our work suggests a potential risk of SARS-CoV re-emergence from viruses currently
78
+ circulating in bat populations.'
79
+ - 'passage: title: The unintended consequences of COVID-19 vaccine policy: why mandates,
80
+ passports and restrictions may cause more harm than good abstract: Vaccination
81
+ policies have shifted dramatically during COVID-19 with the rapid emergence of
82
+ population-wide vaccine mandates, domestic vaccine passports and differential
83
+ restrictions based on vaccination status.
84
+
85
+ While these policies have prompted ethical, scientific, practical, legal and political
86
+ debate, there has been limited evaluation of their potential unintended consequences.
87
+
88
+ Here, we outline a comprehensive set of hypotheses for why these policies may
89
+ ultimately be counterproductive and harmful.
90
+
91
+ Our framework considers four domains: (1) behavioural psychology, (2) politics
92
+ and law, (3) socioeconomics, and (4) the integrity of science and public health.
93
+
94
+ While current vaccines appear to have had a significant impact on decreasing COVID-19-related
95
+ morbidity and mortality burdens, we argue that current mandatory vaccine policies
96
+ are scientifically questionable and are likely to cause more societal harm than
97
+ good.
98
+
99
+ Restricting people’s access to work, education, public transport and social life
100
+ based on COVID-19 vaccination status impinges on human rights, promotes stigma
101
+ and social polarisation, and adversely affects health and well-being.
102
+
103
+ Current policies may lead to a widening of health and economic inequalities, detrimental
104
+ long-term impacts on trust in government and scientific institutions, and reduce
105
+ the uptake of future public health measures, including COVID-19 vaccines as well
106
+ as routine immunisations.
107
+
108
+ Mandating vaccination is one of the most powerful interventions in public health
109
+ and should be used sparingly and carefully to uphold ethical norms and trust in
110
+ institutions.'
111
+ - source_sentence: 'query: @VanessaBeeley No vaccine ! Results indicate following
112
+ standard case of light COVID-19, SARSCOV2 CD8+ Tcells not only persist but steadily
113
+ differentiate in a synchronized manner deep into convalescence into a state characteristic
114
+ of long-lived, self-renewing memory.'
115
+ sentences:
116
+ - 'passage: title: Protracted yet Coordinated Differentiation of Long-Lived SARS-CoV-2-Specific
117
+ CD8+ T Cells during Convalescence abstract: Abstract CD8+ T cells can potentiate
118
+ long-lived immunity against COVID-19.
119
+
120
+ We screened longitudinally-sampled convalescent human donors against SARS-CoV-2
121
+ tetramers and identified a participant with an immunodominant response against
122
+ residues 322 to 311 of nucleocapsid (Nuc322–331), a peptide conserved in all variants
123
+ of concern reported to date.
124
+
125
+ We conducted 38-parameter cytometry by time of flight on tetramer-identified Nuc322–331–specific
126
+ CD8+ T cells and on CD4+ and CD8+ T cells recognizing the entire nucleocapsid
127
+ and spike proteins, and took 32 serological measurements.
128
+
129
+ We discovered a coordination of the Nuc322–331–specific CD8+ T response with both
130
+ the CD4+ T cell and Ab pillars of adaptive immunity.
131
+
132
+ Over the approximately six month period of convalescence monitored, we observed
133
+ a slow and progressive decrease in the activation state and polyfunctionality
134
+ of Nuc322–331–specific CD8+ T cells, accompanied by an increase in their lymph
135
+ node–homing and homeostatic proliferation potential.
136
+
137
+ These results suggest that following a typical case of mild COVID-19, SARS-CoV-2–specific
138
+ CD8+ T cells not only persist but continuously differentiate in a coordinated
139
+ fashion well into convalescence into a state characteristic of long-lived, self-renewing
140
+ memory.'
141
+ - 'passage: publication has also been changed; recommendations are now ordered by
142
+ severity of covid-19.
143
+
144
+
145
+ About this guideline This living guideline from the World Health Organization
146
+ (WHO) incorporates new evidence to dynamically update recommendations for covid-19
147
+ therapeutics.
148
+
149
+ The GDG typically evaluates a therapy when the WHO judges sufficient evidence
150
+ is available to make a recommendation.
151
+
152
+ While the GDG takes an individual patient perspective in making recommendations,
153
+ it also considers resource implications, acceptability, feasibility, equity, and
154
+ human rights.
155
+
156
+ This guideline was developed according to standards and methods for trustworthy
157
+ guidelines, making use of an innovative process to achieve efficiency in dynamic
158
+ updating of recommendations.
159
+
160
+ The methods are aligned with the WHO Handbook for Guideline Development and according
161
+ to a pre-approved protocol (planning proposal) by the Guideline Review Committee
162
+ (GRC).
163
+
164
+ A box at the end of the article outlines key methodological aspects of the guideline
165
+ process.
166
+
167
+ MAGIC Evidence Ecosystem Foundation provides methodological support, including
168
+ the coordination of living systematic reviews with network meta-analyses to inform
169
+ the recommendations.
170
+
171
+ The full version of the guideline is available online in MAGICapp and in PDF on
172
+ the WHO website, with a summary version here in The BMJ .
173
+
174
+ These formats should facilitate adaptation, which is strongly encouraged by WHO
175
+ to contextualise recommendations in a healthcare system to maximise impact.
176
+
177
+ Future recommendations Recommendations on anticoagulation are planned for the
178
+ next update to this guideline.
179
+
180
+ Updated data regarding systemic corticosteroids, azithromycin, favipiravir and
181
+ umefenovir for non-severe illness, and convalescent plasma and statin therapy
182
+ for severe or critical illness, are planned for review in upcoming guideline iterations.'
183
+ - 'passage: title: Understanding the Effects of Age and T-Cell Differentiation on
184
+ COVID-19 Severity: Implicating a Fas/FasL-mediated Feed-Forward Controller of
185
+ T-Cell Differentiation abstract: OPINION article Front.
186
+
187
+ Immunol.
188
+
189
+ , 03 March 2022Sec.
190
+
191
+ T Cell Biology Volume 13 - 2022 | https://doi.
192
+
193
+ org/10.
194
+
195
+ 3389/fimmu.
196
+
197
+ 2022.'
198
+ - source_sentence: 'query: Preprint:Beschwerden nach Covid-Impfung🧵 "Von den 1 704
199
+ teilnehmenden Beschäftigten des Gesundheitswesens waren insgesamt 595 (34,9 %)
200
+ nach mindestens einer COVID‑19‑Impfung krankgeschrieben, was zu einer Gesamtzahl
201
+ von 1 550 Krankheitstagen führte."'
202
+ sentences:
203
+ - 'passage: title: Projecting the transmission dynamics of SARS-CoV-2 through the
204
+ postpandemic period abstract: It is urgent to understand the future of severe
205
+ acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) transmission.
206
+
207
+ We used estimates of seasonality, immunity, and cross-immunity for human coronavirus
208
+ OC43 (HCoV-OC43) and HCoV-HKU1 using time-series data from the United States to
209
+ inform a model of SARS-CoV-2 transmission.
210
+
211
+ We projected that recurrent wintertime outbreaks of SARS-CoV-2 will probably occur
212
+ after the initial, most severe pandemic wave.
213
+
214
+ Absent other interventions, a key metric for the success of social distancing
215
+ is whether critical care capacities are exceeded.
216
+
217
+ To avoid this, prolonged or intermittent social distancing may be necessary into
218
+ 2022.
219
+
220
+ Additional interventions, including expanded critical care capacity and an effective
221
+ therapeutic, would improve the success of intermittent distancing and hasten the
222
+ acquisition of herd immunity.
223
+
224
+ Longitudinal serological studies are urgently needed to determine the extent and
225
+ duration of immunity to SARS-CoV-2.
226
+
227
+ Even in the event of apparent elimination, SARS-CoV-2 surveillance should be maintained
228
+ because a resurgence in contagion could be possible as late as 2024.'
229
+ - 'passage: title: Inability to work following COVID-19 vaccination among healthcare
230
+ workers - an important aspect for future booster vaccinations abstract: ABSTRACT
231
+ Background COVID-19 vaccination is a key prevention strategy to reduce the spread
232
+ and severity of SARS-CoV-2 infections, especially among highly exposed healthcare
233
+ workers (HCWs).
234
+
235
+ However, vaccine-related inability to work among HCWs could overstrain healthcare
236
+ systems.
237
+
238
+ Methods This study examined sick leave and intake of pro re nata (PRN) medication
239
+ after the first, second and third COVID-19 vaccination in HCWs.
240
+
241
+ Subgroup analyses were performed for different vaccines, gender, healthcare professions,
242
+ and for HCWs aged at least 30 years.
243
+
244
+ Data was collected by using an electronic questionnaire.
245
+
246
+ Findings Among 1,704 HCWs enrolled, in total 595 (34·9%) HCWs were on sick leave
247
+ following at least one COVID-19 vaccination, leading to a total number of 1,550
248
+ sick days.
249
+
250
+ Both the absolute sick days and the rate of HCWs on sick leave significantly increased
251
+ with each subsequent vaccination.
252
+
253
+ Comparing BNT162b2mRNA and mRNA-1273 the difference in sick leave was not significant
254
+ after the second dose, but mRNA-1273 induced a significantly longer and more frequent
255
+ sick leave after the third.
256
+
257
+ Interpretation A considerable number of HCWs have been on sick leave after COVID-19
258
+ vaccination, staff absences increase with each additional dose, depend on the
259
+ vaccine, and vary between HCWs’ gender, and profession.
260
+
261
+ In the light of further COVID-19 infection waves and booster vaccinations, there
262
+ is a risk of additional staff shortages due to post-vaccination inability to work,
263
+ which could acutely overload healthcare systems and jeopardise patient care.'
264
+ - 'passage: title: Plasma proteomic profiling in postural orthostatic tachycardia
265
+ syndrome (POTS) reveals new disease pathways abstract: Abstract Postural orthostatic
266
+ tachycardia syndrome (POTS) is a cardiovascular autonomic disorder characterized
267
+ by excessive heart rate increase on standing, leading to debilitating symptoms
268
+ with limited therapeutic possibilities.
269
+
270
+ Proteomics is a large-scale study of proteins that enables a systematic unbiased
271
+ view on disease and health, allowing stratification of patients based on their
272
+ protein background.
273
+
274
+ The aim of the present study was to determine plasma protein biomarkers of POTS
275
+ and to reveal proteomic pathways differentially regulated in POTS.
276
+
277
+ We performed an age- and sex-matched, case–control study in 130 individuals (case–control
278
+ ratio 1:1) including POTS and healthy controls.
279
+
280
+ Mean age in POTS was 30 ± 9.
281
+
282
+ 8 years (84.
283
+
284
+ 6% women) versus controls 31 ± 9.
285
+
286
+ 8 years (80.
287
+
288
+ 0% women).
289
+
290
+ We analyzed plasma proteins using data-independent acquisition (DIA) mass spectrometry.
291
+
292
+ Pathway analysis of significantly differently expressed proteins was executed
293
+ using a cutoff log2 fold change set to 1.
294
+
295
+ 2 and false discovery rate (p-value) of < 0.
296
+
297
+ 05.
298
+
299
+ A total of 393 differential plasma proteins were identified.
300
+
301
+ Label-free quantification of DIA-data identified 30 differentially expressed proteins
302
+ in POTS compared with healthy controls.
303
+
304
+ Pathway analysis identified the strongest network interactions particularly for
305
+ proteins involved in thrombogenicity and enhanced platelet activity, but also
306
+ inflammation, cardiac contractility and hypertrophy, and increased adrenergic
307
+ activity.'
308
+ - source_sentence: 'query: Nachträglich hat bei uns in FRA das Testen von Reisenden
309
+ mit AG‑Test und fachmännischem NP‑Abstrich ausgezeichnet funktioniert: SARS‑CoV‑2
310
+ screening strategies for returning international travellers: Evaluation of a rapid
311
+ antigen test approach.'
312
+ sentences:
313
+ - 'passage: title: SARS-CoV-2 screening strategies for returning international travellers:
314
+ Evaluation of a rapid antigen test approach abstract: International travel poses
315
+ the risk of importing SARS-CoV-2 infections and introducing new viral variants
316
+ into the country of destination.
317
+
318
+ Established measures include mandatory quarantine with the opportunity to abbreviate
319
+ it with a negative rapid antigen test (RAT).
320
+
321
+ A total of 1,488 returnees were tested for SARS-CoV-2 with both PCR and RAT no
322
+ earlier than 5 days after arrival.
323
+
324
+ We assessed the sensitivity and specificity of the RAT.
325
+
326
+ Positive samples were evaluated for infectivity in vitro in a cell culture outgrowth
327
+ assay.
328
+
329
+ We tracked if participants who tested negative were reported positive within 2
330
+ weeks of the initial test.
331
+
332
+ Potential infectiousness was determined based on symptom onset analysis, resulting
333
+ in a sensitivity of the antigen test of 89% in terms of infectivity.
334
+
335
+ The specificity was 100%.
336
+
337
+ All positive outgrowth assays were preceded by a positive RAT, indicating that
338
+ all participants with proven in vitro infectivity were correctly identified.
339
+
340
+ None of the negative participants tested positive during the follow-up.
341
+
342
+ RAT no earlier than the 5th day after arrival was a reliable method for detecting
343
+ infectious travellers and can be recommended as an appropriate method for managing
344
+ SARS-CoV-2 travel restrictions.
345
+
346
+ Compliance to the regulations and a high standard of test quality must be ensured.'
347
+ - 'passage: title: Persistence and Evolution of SARS-CoV-2 in an Immunocompromised
348
+ Host abstract: SARS-CoV-2 in an Immunocompromised Host This letter describes an
349
+ immunocompromised patient who had persistent infection with SARS-CoV-2 over a
350
+ period of months, despite several courses of remdesivi.'
351
+ - 'passage: title: Imperfect Vaccination Can Enhance the Transmission of Highly
352
+ Virulent Pathogens abstract: Could some vaccines drive the evolution of more virulent
353
+ pathogens?
354
+
355
+ Conventional wisdom is that natural selection will remove highly lethal pathogens
356
+ if host death greatly reduces transmission.
357
+
358
+ Vaccines that keep hosts alive but still allow transmission could thus allow very
359
+ virulent strains to circulate in a population.
360
+
361
+ Here we show experimentally that immunization of chickens against Marek''s disease
362
+ virus enhances the fitness of more virulent strains, making it possible for hyperpathogenic
363
+ strains to transmit.
364
+
365
+ Immunity elicited by direct vaccination or by maternal vaccination prolongs host
366
+ survival but does not prevent infection, viral replication or transmission, thus
367
+ extending the infectious periods of strains otherwise too lethal to persist.
368
+
369
+ Our data show that anti-disease vaccines that do not prevent transmission can
370
+ create conditions that promote the emergence of pathogen strains that cause more
371
+ severe disease in unvaccinated hosts.'
372
+ - source_sentence: 'query: @zoeharcombe I''ll reply it. The "vaccines" have no health
373
+ benefit and only cause harm. Pharma company trial data says they don''t work.
374
+ A straightforward calculation of absolute risk from the Pfizer trial data = .04%
375
+ effectiveness for severe cases, which is essentially zero.'
376
+ sentences:
377
+ - 'passage: Among 10 cases of severe Covid-19 with onset after the first dose, 9
378
+ occurred in placebo recipients and 1 in a BNT162b2 recipient.
379
+
380
+
381
+ The safety profile of BNT162b2 was characterized by short-term, mild-to-moderate
382
+ pain at the injection site, fatigue, and headache.
383
+
384
+ The incidence of serious adverse events was low and was similar in the vaccine
385
+ and placebo groups.
386
+
387
+ ConclusionsA two-dose regimen of BNT162b2 conferred 95% protection against Covid-19
388
+ in persons 16 years of age or older.
389
+
390
+ Safety over a median of 2 months was similar to that of other viral vaccines.
391
+
392
+ (Funded by BioNTech and Pfizer; ClinicalTrials.
393
+
394
+ gov number, NCT04368728.'
395
+ - 'passage: title: Brain lesions disrupting addiction map to a common human brain
396
+ circuit abstract: Abstract Drug addiction is a public health crisis for which
397
+ new treatments are urgently needed.
398
+
399
+ In rare cases, regional brain damage can lead to addiction remission.
400
+
401
+ These cases may be used to identify therapeutic targets for neuromodulation.
402
+
403
+ We analyzed two cohorts of patients addicted to smoking at the time of focal brain
404
+ damage (cohort 1 n = 67; cohort 2 n = 62).
405
+
406
+ Lesion locations were mapped to a brain atlas and the brain network functionally
407
+ connected to each lesion location was computed using human connectome data ( n
408
+ = 1,000).
409
+
410
+ Associations with addiction remission were identified.
411
+
412
+ Generalizability was assessed using an independent cohort of patients with focal
413
+ brain damage and alcohol addiction risk scores ( n = 186).
414
+
415
+ Specificity was assessed through comparison to 37 other neuropsychological variables.
416
+
417
+ Lesions disrupting smoking addiction occurred in many different brain locations
418
+ but were characterized by a specific pattern of brain connectivity.
419
+
420
+ This pattern involved positive connectivity to the dorsal cingulate, lateral prefrontal
421
+ cortex, and insula and negative connectivity to the medial prefrontal and temporal
422
+ cortex.
423
+
424
+ This circuit was reproducible across independent lesion cohorts, associated with
425
+ reduced alcohol addiction risk, and specific to addiction metrics.
426
+
427
+ Hubs that best matched the connectivity profile for addiction remission were the
428
+ paracingulate gyrus, left frontal operculum, and medial fronto-polar cortex.
429
+
430
+ We conclude that brain lesions disrupting addiction map to a specific human brain
431
+ circuit and that hubs in this circuit provide testable targets for therapeutic
432
+ neuromodulation.'
433
+ - 'passage: title: Imperfect Vaccination Can Enhance the Transmission of Highly
434
+ Virulent Pathogens abstract: Could some vaccines drive the evolution of more virulent
435
+ pathogens?
436
+
437
+ Conventional wisdom is that natural selection will remove highly lethal pathogens
438
+ if host death greatly reduces transmission.
439
+
440
+ Vaccines that keep hosts alive but still allow transmission could thus allow very
441
+ virulent strains to circulate in a population.
442
+
443
+ Here we show experimentally that immunization of chickens against Marek''s disease
444
+ virus enhances the fitness of more virulent strains, making it possible for hyperpathogenic
445
+ strains to transmit.
446
+
447
+ Immunity elicited by direct vaccination or by maternal vaccination prolongs host
448
+ survival but does not prevent infection, viral replication or transmission, thus
449
+ extending the infectious periods of strains otherwise too lethal to persist.
450
+
451
+ Our data show that anti-disease vaccines that do not prevent transmission can
452
+ create conditions that promote the emergence of pathogen strains that cause more
453
+ severe disease in unvaccinated hosts.'
454
+ pipeline_tag: sentence-similarity
455
+ library_name: sentence-transformers
456
+ metrics:
457
+ - cosine_accuracy@1
458
+ - cosine_accuracy@3
459
+ - cosine_accuracy@5
460
+ - cosine_accuracy@10
461
+ - cosine_precision@1
462
+ - cosine_precision@3
463
+ - cosine_precision@5
464
+ - cosine_precision@10
465
+ - cosine_recall@1
466
+ - cosine_recall@3
467
+ - cosine_recall@5
468
+ - cosine_recall@10
469
+ - cosine_ndcg@10
470
+ - cosine_mrr@10
471
+ - cosine_map@100
472
+ model-index:
473
+ - name: SentenceTransformer based on intfloat/multilingual-e5-large
474
+ results:
475
+ - task:
476
+ type: information-retrieval
477
+ name: Information Retrieval
478
+ dataset:
479
+ name: 10 percent dev split
480
+ type: 10-percent-dev-split
481
+ metrics:
482
+ - type: cosine_accuracy@1
483
+ value: 0.52
484
+ name: Cosine Accuracy@1
485
+ - type: cosine_accuracy@3
486
+ value: 0.7215584415584415
487
+ name: Cosine Accuracy@3
488
+ - type: cosine_accuracy@5
489
+ value: 0.7937662337662338
490
+ name: Cosine Accuracy@5
491
+ - type: cosine_accuracy@10
492
+ value: 0.8493506493506493
493
+ name: Cosine Accuracy@10
494
+ - type: cosine_precision@1
495
+ value: 0.52
496
+ name: Cosine Precision@1
497
+ - type: cosine_precision@3
498
+ value: 0.24051948051948052
499
+ name: Cosine Precision@3
500
+ - type: cosine_precision@5
501
+ value: 0.15875324675324673
502
+ name: Cosine Precision@5
503
+ - type: cosine_precision@10
504
+ value: 0.08493506493506493
505
+ name: Cosine Precision@10
506
+ - type: cosine_recall@1
507
+ value: 0.52
508
+ name: Cosine Recall@1
509
+ - type: cosine_recall@3
510
+ value: 0.7215584415584415
511
+ name: Cosine Recall@3
512
+ - type: cosine_recall@5
513
+ value: 0.7937662337662338
514
+ name: Cosine Recall@5
515
+ - type: cosine_recall@10
516
+ value: 0.8493506493506493
517
+ name: Cosine Recall@10
518
+ - type: cosine_ndcg@10
519
+ value: 0.6862946585295414
520
+ name: Cosine Ndcg@10
521
+ - type: cosine_mrr@10
522
+ value: 0.6337252112966393
523
+ name: Cosine Mrr@10
524
+ - type: cosine_map@100
525
+ value: 0.6389157727076894
526
+ name: Cosine Map@100
527
+ ---
528
+
529
+ # SentenceTransformer based on intfloat/multilingual-e5-large
530
+
531
+ This is a [sentence-transformers](https://www.SBERT.net) model finetuned from [intfloat/multilingual-e5-large](https://huggingface.co/intfloat/multilingual-e5-large). It maps sentences & paragraphs to a 1024-dimensional dense vector space and can be used for semantic textual similarity, semantic search, paraphrase mining, text classification, clustering, and more.
532
+
533
+ ## Model Details
534
+
535
+ ### Model Description
536
+ - **Model Type:** Sentence Transformer
537
+ - **Base model:** [intfloat/multilingual-e5-large](https://huggingface.co/intfloat/multilingual-e5-large) <!-- at revision 3d7cfbdacd47fdda877c5cd8a79fbcc4f2a574f3 -->
538
+ - **Maximum Sequence Length:** 256 tokens
539
+ - **Output Dimensionality:** 1024 dimensions
540
+ - **Similarity Function:** Cosine Similarity
541
+ <!-- - **Training Dataset:** Unknown -->
542
+ <!-- - **Language:** Unknown -->
543
+ <!-- - **License:** Unknown -->
544
+
545
+ ### Model Sources
546
+
547
+ - **Documentation:** [Sentence Transformers Documentation](https://sbert.net)
548
+ - **Repository:** [Sentence Transformers on GitHub](https://github.com/huggingface/sentence-transformers)
549
+ - **Hugging Face:** [Sentence Transformers on Hugging Face](https://huggingface.co/models?library=sentence-transformers)
550
+
551
+ ### Full Model Architecture
552
+
553
+ ```
554
+ SentenceTransformer(
555
+ (0): Transformer({'max_seq_length': 256, 'do_lower_case': False, 'architecture': 'PeftModelForFeatureExtraction'})
556
+ (1): Pooling({'word_embedding_dimension': 1024, 'pooling_mode_cls_token': False, 'pooling_mode_mean_tokens': True, 'pooling_mode_max_tokens': False, 'pooling_mode_mean_sqrt_len_tokens': False, 'pooling_mode_weightedmean_tokens': False, 'pooling_mode_lasttoken': False, 'include_prompt': True})
557
+ (2): Normalize()
558
+ )
559
+ ```
560
+
561
+ ## Usage
562
+
563
+ ### Direct Usage (Sentence Transformers)
564
+
565
+ First install the Sentence Transformers library:
566
+
567
+ ```bash
568
+ pip install -U sentence-transformers
569
+ ```
570
+
571
+ Then you can load this model and run inference.
572
+ ```python
573
+ from sentence_transformers import SentenceTransformer
574
+
575
+ # Download from the 🤗 Hub
576
+ model = SentenceTransformer("songphucn7/me5-checkthat-task1-v2")
577
+ # Run inference
578
+ sentences = [
579
+ 'query: @zoeharcombe I\'ll reply it. The "vaccines" have no health benefit and only cause harm. Pharma company trial data says they don\'t work. A straightforward calculation of absolute risk from the Pfizer trial data = .04% effectiveness for severe cases, which is essentially zero.',
580
+ 'passage: Among 10 cases of severe Covid-19 with onset after the first dose, 9 occurred in placebo recipients and 1 in a BNT162b2 recipient.\n\nThe safety profile of BNT162b2 was characterized by short-term, mild-to-moderate pain at the injection site, fatigue, and headache.\nThe incidence of serious adverse events was low and was similar in the vaccine and placebo groups.\nConclusionsA two-dose regimen of BNT162b2 conferred 95% protection against Covid-19 in persons 16 years of age or older.\nSafety over a median of 2 months was similar to that of other viral vaccines.\n(Funded by BioNTech and Pfizer; ClinicalTrials.\ngov number, NCT04368728.',
581
+ "passage: title: Imperfect Vaccination Can Enhance the Transmission of Highly Virulent Pathogens abstract: Could some vaccines drive the evolution of more virulent pathogens?\nConventional wisdom is that natural selection will remove highly lethal pathogens if host death greatly reduces transmission.\nVaccines that keep hosts alive but still allow transmission could thus allow very virulent strains to circulate in a population.\nHere we show experimentally that immunization of chickens against Marek's disease virus enhances the fitness of more virulent strains, making it possible for hyperpathogenic strains to transmit.\nImmunity elicited by direct vaccination or by maternal vaccination prolongs host survival but does not prevent infection, viral replication or transmission, thus extending the infectious periods of strains otherwise too lethal to persist.\nOur data show that anti-disease vaccines that do not prevent transmission can create conditions that promote the emergence of pathogen strains that cause more severe disease in unvaccinated hosts.",
582
+ ]
583
+ embeddings = model.encode(sentences)
584
+ print(embeddings.shape)
585
+ # [3, 1024]
586
+
587
+ # Get the similarity scores for the embeddings
588
+ similarities = model.similarity(embeddings, embeddings)
589
+ print(similarities)
590
+ # tensor([[1.0000, 0.5866, 0.3283],
591
+ # [0.5866, 1.0000, 0.1368],
592
+ # [0.3283, 0.1368, 1.0000]])
593
+ ```
594
+
595
+ <!--
596
+ ### Direct Usage (Transformers)
597
+
598
+ <details><summary>Click to see the direct usage in Transformers</summary>
599
+
600
+ </details>
601
+ -->
602
+
603
+ <!--
604
+ ### Downstream Usage (Sentence Transformers)
605
+
606
+ You can finetune this model on your own dataset.
607
+
608
+ <details><summary>Click to expand</summary>
609
+
610
+ </details>
611
+ -->
612
+
613
+ <!--
614
+ ### Out-of-Scope Use
615
+
616
+ *List how the model may foreseeably be misused and address what users ought not to do with the model.*
617
+ -->
618
+
619
+ ## Evaluation
620
+
621
+ ### Metrics
622
+
623
+ #### Information Retrieval
624
+
625
+ * Dataset: `10-percent-dev-split`
626
+ * Evaluated with [<code>InformationRetrievalEvaluator</code>](https://sbert.net/docs/package_reference/sentence_transformer/evaluation.html#sentence_transformers.evaluation.InformationRetrievalEvaluator)
627
+
628
+ | Metric | Value |
629
+ |:--------------------|:-----------|
630
+ | cosine_accuracy@1 | 0.52 |
631
+ | cosine_accuracy@3 | 0.7216 |
632
+ | cosine_accuracy@5 | 0.7938 |
633
+ | cosine_accuracy@10 | 0.8494 |
634
+ | cosine_precision@1 | 0.52 |
635
+ | cosine_precision@3 | 0.2405 |
636
+ | cosine_precision@5 | 0.1588 |
637
+ | cosine_precision@10 | 0.0849 |
638
+ | cosine_recall@1 | 0.52 |
639
+ | cosine_recall@3 | 0.7216 |
640
+ | cosine_recall@5 | 0.7938 |
641
+ | cosine_recall@10 | 0.8494 |
642
+ | **cosine_ndcg@10** | **0.6863** |
643
+ | cosine_mrr@10 | 0.6337 |
644
+ | cosine_map@100 | 0.6389 |
645
+
646
+ <!--
647
+ ## Bias, Risks and Limitations
648
+
649
+ *What are the known or foreseeable issues stemming from this model? You could also flag here known failure cases or weaknesses of the model.*
650
+ -->
651
+
652
+ <!--
653
+ ### Recommendations
654
+
655
+ *What are recommendations with respect to the foreseeable issues? For example, filtering explicit content.*
656
+ -->
657
+
658
+ ## Training Details
659
+
660
+ ### Training Dataset
661
+
662
+ #### Unnamed Dataset
663
+
664
+ * Size: 17,319 training samples
665
+ * Columns: <code>sentence_0</code> and <code>sentence_1</code>
666
+ * Approximate statistics based on the first 1000 samples:
667
+ | | sentence_0 | sentence_1 |
668
+ |:--------|:-----------------------------------------------------------------------------------|:------------------------------------------------------------------------------------|
669
+ | type | string | string |
670
+ | details | <ul><li>min: 21 tokens</li><li>mean: 59.2 tokens</li><li>max: 136 tokens</li></ul> | <ul><li>min: 11 tokens</li><li>mean: 205.0 tokens</li><li>max: 256 tokens</li></ul> |
671
+ * Samples:
672
+ | sentence_0 | sentence_1 |
673
+ |:---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|:------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
674
+ | <code>query: @user Baloney. Natural immunity is hands down better, and vaccinated people are ending up in the hospital.</code> | <code>passage: title: Longitudinal analysis shows durable and broad immune memory after SARS-CoV-2 infection with persisting antibody responses and memory B and T cells abstract: Ending the COVID-19 pandemic will require long-lived immunity to SARS-CoV-2.<br>Here, we evaluate 254 COVID-19 patients longitudinally up to 8 months and find durable broad-based immune responses.<br>SARS-CoV-2 spike binding and neutralizing antibodies exhibit a bi-phasic decay with an extended half-life of >200 days suggesting the generation of longer-lived plasma cells.<br>SARS-CoV-2 infection also boosts antibody titers to SARS-CoV-1 and common betacoronaviruses.<br>In addition, spike-specific IgG+ memory B cells persist, which bodes well for a rapid antibody response upon virus re-exposure or vaccination.<br>Virus-specific CD4+ and CD8+ T cells are polyfunctional and maintained with an estimated half-life of 200 days.<br>Interestingly, CD4+ T cell responses equally target several SARS-CoV-2 proteins, whereas the CD8+ T cell respo...</code> |
675
+ | <code>query: @Alexand64744343 Meta examen tests #lyme + élevé niveau de preuve scientifique ! : rendement « 53.9% for synthetic C6 peptide ELISA tests & 53.7% when the two-tier methodology was used » Une véritable loterie, 1 cas sur 2 détecté mais persistez à vociférer par ignorance</code> | <code>passage: title: Commercial test kits for detection of Lyme borreliosis: a meta-analysis of test accuracy abstract: The clinical diagnosis of Lyme borreliosis can be supported by various test methodologies; test kits are available from many manufacturers.<br>Literature searches were carried out to identify studies that reported characteristics of the test kits.<br>Of 50 searched studies, 18 were included where the tests were commercially available and samples were proven to be positive using serology testing, evidence of an erythema migrans rash, and/or culture.<br>Additional requirements were a test specificity of ≥85% and publication in the last 20 years.<br>The weighted mean sensitivity for all tests and for all samples was 59.<br>5%.<br>Individual study means varied from 30.<br>6% to 86.<br>2%.<br>Sensitivity for each test technology varied from 62.<br>4% for Western blot kits, and 62.<br>3% for enzyme-linked immunosorbent assay tests, to 53.<br>9% for synthetic C6 peptide ELISA tests and 53.<br>7% when the two-tier meth...</code> |
676
+ | <code>query: 28 Les systèmes de séquençage haut débit qui servent à la production des banques comme celles du papier de Jaenisch produisent des chimères artefactuelles lors de la PCR. C’est bien connu. Discuté dans :</code> | <code>passage: title: A Survey of Virus Recombination Uncovers Canonical Features of Artificial Chimeras Generated During Deep Sequencing Library Preparation abstract: Abstract Chimeric reads can be generated by in vitro recombination during the preparation of high-throughput sequencing libraries.<br>Our attempt to detect biological recombination between the genomes of dengue virus (DENV; +ssRNA genome) and its mosquito host using the Illumina Nextera sequencing library preparation kit revealed that most, if not all, detected host–virus chimeras were artificial.<br>Indeed, these chimeras were not more frequent than with control RNA from another species (a pillbug), which was never in contact with DENV RNA prior to the library preparation.<br>The proportion of chimera types merely reflected those of the three species among sequencing reads.<br>Chimeras were frequently characterized by the presence of 1-20 bp microhomology between recombining fragments.<br>Within-species chimeras mostly involved fragments in...</code> |
677
+ * Loss: [<code>MultipleNegativesRankingLoss</code>](https://sbert.net/docs/package_reference/sentence_transformer/losses.html#multiplenegativesrankingloss) with these parameters:
678
+ ```json
679
+ {
680
+ "scale": 20.0,
681
+ "similarity_fct": "cos_sim",
682
+ "gather_across_devices": false,
683
+ "directions": [
684
+ "query_to_doc"
685
+ ],
686
+ "partition_mode": "joint",
687
+ "hardness_mode": null,
688
+ "hardness_strength": 0.0
689
+ }
690
+ ```
691
+
692
+ ### Training Hyperparameters
693
+ #### Non-Default Hyperparameters
694
+
695
+ - `per_device_train_batch_size`: 32
696
+ - `num_train_epochs`: 10
697
+ - `eval_strategy`: steps
698
+ - `per_device_eval_batch_size`: 32
699
+ - `multi_dataset_batch_sampler`: round_robin
700
+
701
+ #### All Hyperparameters
702
+ <details><summary>Click to expand</summary>
703
+
704
+ - `per_device_train_batch_size`: 32
705
+ - `num_train_epochs`: 10
706
+ - `max_steps`: -1
707
+ - `learning_rate`: 5e-05
708
+ - `lr_scheduler_type`: linear
709
+ - `lr_scheduler_kwargs`: None
710
+ - `warmup_steps`: 0
711
+ - `optim`: adamw_torch_fused
712
+ - `optim_args`: None
713
+ - `weight_decay`: 0.0
714
+ - `adam_beta1`: 0.9
715
+ - `adam_beta2`: 0.999
716
+ - `adam_epsilon`: 1e-08
717
+ - `optim_target_modules`: None
718
+ - `gradient_accumulation_steps`: 1
719
+ - `average_tokens_across_devices`: True
720
+ - `max_grad_norm`: 1
721
+ - `label_smoothing_factor`: 0.0
722
+ - `bf16`: False
723
+ - `fp16`: False
724
+ - `bf16_full_eval`: False
725
+ - `fp16_full_eval`: False
726
+ - `tf32`: None
727
+ - `gradient_checkpointing`: False
728
+ - `gradient_checkpointing_kwargs`: None
729
+ - `torch_compile`: False
730
+ - `torch_compile_backend`: None
731
+ - `torch_compile_mode`: None
732
+ - `use_liger_kernel`: False
733
+ - `liger_kernel_config`: None
734
+ - `use_cache`: False
735
+ - `neftune_noise_alpha`: None
736
+ - `torch_empty_cache_steps`: None
737
+ - `auto_find_batch_size`: False
738
+ - `log_on_each_node`: True
739
+ - `logging_nan_inf_filter`: True
740
+ - `include_num_input_tokens_seen`: no
741
+ - `log_level`: passive
742
+ - `log_level_replica`: warning
743
+ - `disable_tqdm`: False
744
+ - `project`: huggingface
745
+ - `trackio_space_id`: trackio
746
+ - `eval_strategy`: steps
747
+ - `per_device_eval_batch_size`: 32
748
+ - `prediction_loss_only`: True
749
+ - `eval_on_start`: False
750
+ - `eval_do_concat_batches`: True
751
+ - `eval_use_gather_object`: False
752
+ - `eval_accumulation_steps`: None
753
+ - `include_for_metrics`: []
754
+ - `batch_eval_metrics`: False
755
+ - `save_only_model`: False
756
+ - `save_on_each_node`: False
757
+ - `enable_jit_checkpoint`: False
758
+ - `push_to_hub`: False
759
+ - `hub_private_repo`: None
760
+ - `hub_model_id`: None
761
+ - `hub_strategy`: every_save
762
+ - `hub_always_push`: False
763
+ - `hub_revision`: None
764
+ - `load_best_model_at_end`: False
765
+ - `ignore_data_skip`: False
766
+ - `restore_callback_states_from_checkpoint`: False
767
+ - `full_determinism`: False
768
+ - `seed`: 42
769
+ - `data_seed`: None
770
+ - `use_cpu`: False
771
+ - `accelerator_config`: {'split_batches': False, 'dispatch_batches': None, 'even_batches': True, 'use_seedable_sampler': True, 'non_blocking': False, 'gradient_accumulation_kwargs': None}
772
+ - `parallelism_config`: None
773
+ - `dataloader_drop_last`: False
774
+ - `dataloader_num_workers`: 0
775
+ - `dataloader_pin_memory`: True
776
+ - `dataloader_persistent_workers`: False
777
+ - `dataloader_prefetch_factor`: None
778
+ - `remove_unused_columns`: True
779
+ - `label_names`: None
780
+ - `train_sampling_strategy`: random
781
+ - `length_column_name`: length
782
+ - `ddp_find_unused_parameters`: None
783
+ - `ddp_bucket_cap_mb`: None
784
+ - `ddp_broadcast_buffers`: False
785
+ - `ddp_backend`: None
786
+ - `ddp_timeout`: 1800
787
+ - `fsdp`: []
788
+ - `fsdp_config`: {'min_num_params': 0, 'xla': False, 'xla_fsdp_v2': False, 'xla_fsdp_grad_ckpt': False}
789
+ - `deepspeed`: None
790
+ - `debug`: []
791
+ - `skip_memory_metrics`: True
792
+ - `do_predict`: False
793
+ - `resume_from_checkpoint`: None
794
+ - `warmup_ratio`: None
795
+ - `local_rank`: -1
796
+ - `prompts`: None
797
+ - `batch_sampler`: batch_sampler
798
+ - `multi_dataset_batch_sampler`: round_robin
799
+ - `router_mapping`: {}
800
+ - `learning_rate_mapping`: {}
801
+
802
+ </details>
803
+
804
+ ### Training Logs
805
+ | Epoch | Step | Training Loss | 10-percent-dev-split_cosine_ndcg@10 |
806
+ |:------:|:----:|:-------------:|:-----------------------------------:|
807
+ | 0.1845 | 100 | - | 0.6380 |
808
+ | 0.3690 | 200 | - | 0.6400 |
809
+ | 0.5535 | 300 | - | 0.6512 |
810
+ | 0.7380 | 400 | - | 0.6642 |
811
+ | 0.9225 | 500 | 0.8957 | 0.6640 |
812
+ | 1.0 | 542 | - | 0.6626 |
813
+ | 1.1070 | 600 | - | 0.6658 |
814
+ | 1.2915 | 700 | - | 0.6676 |
815
+ | 1.4760 | 800 | - | 0.6695 |
816
+ | 1.6605 | 900 | - | 0.6719 |
817
+ | 1.8450 | 1000 | 0.3899 | 0.6776 |
818
+ | 2.0 | 1084 | - | 0.6744 |
819
+ | 2.0295 | 1100 | - | 0.6761 |
820
+ | 2.2140 | 1200 | - | 0.6759 |
821
+ | 2.3985 | 1300 | - | 0.6761 |
822
+ | 2.5830 | 1400 | - | 0.6830 |
823
+ | 2.7675 | 1500 | 0.3484 | 0.6779 |
824
+ | 2.9520 | 1600 | - | 0.6793 |
825
+ | 3.0 | 1626 | - | 0.6762 |
826
+ | 3.1365 | 1700 | - | 0.6823 |
827
+ | 3.3210 | 1800 | - | 0.6831 |
828
+ | 3.5055 | 1900 | - | 0.6788 |
829
+ | 3.6900 | 2000 | 0.3083 | 0.6821 |
830
+ | 3.8745 | 2100 | - | 0.6775 |
831
+ | 4.0 | 2168 | - | 0.6788 |
832
+ | 4.0590 | 2200 | - | 0.6786 |
833
+ | 4.2435 | 2300 | - | 0.6792 |
834
+ | 4.4280 | 2400 | - | 0.6827 |
835
+ | 4.6125 | 2500 | 0.3033 | 0.6804 |
836
+ | 4.7970 | 2600 | - | 0.6822 |
837
+ | 4.9815 | 2700 | - | 0.6914 |
838
+ | 5.0 | 2710 | - | 0.6880 |
839
+ | 5.1661 | 2800 | - | 0.6809 |
840
+ | 5.3506 | 2900 | - | 0.6853 |
841
+ | 5.5351 | 3000 | 0.2840 | 0.6852 |
842
+ | 5.7196 | 3100 | - | 0.6844 |
843
+ | 5.9041 | 3200 | - | 0.6886 |
844
+ | 6.0 | 3252 | - | 0.6859 |
845
+ | 6.0886 | 3300 | - | 0.6859 |
846
+ | 6.2731 | 3400 | - | 0.6811 |
847
+ | 6.4576 | 3500 | 0.2669 | 0.6896 |
848
+ | 6.6421 | 3600 | - | 0.6864 |
849
+ | 6.8266 | 3700 | - | 0.6859 |
850
+ | 7.0 | 3794 | - | 0.6893 |
851
+ | 7.0111 | 3800 | - | 0.6907 |
852
+ | 7.1956 | 3900 | - | 0.6865 |
853
+ | 7.3801 | 4000 | 0.2546 | 0.6831 |
854
+ | 7.5646 | 4100 | - | 0.6872 |
855
+ | 7.7491 | 4200 | - | 0.6893 |
856
+ | 7.9336 | 4300 | - | 0.6864 |
857
+ | 8.0 | 4336 | - | 0.6900 |
858
+ | 8.1181 | 4400 | - | 0.6885 |
859
+ | 8.3026 | 4500 | 0.2518 | 0.6857 |
860
+ | 8.4871 | 4600 | - | 0.6874 |
861
+ | 8.6716 | 4700 | - | 0.6834 |
862
+ | 8.8561 | 4800 | - | 0.6859 |
863
+ | 9.0 | 4878 | - | 0.6858 |
864
+ | 9.0406 | 4900 | - | 0.6844 |
865
+ | 9.2251 | 5000 | 0.2392 | 0.6861 |
866
+ | 9.4096 | 5100 | - | 0.6874 |
867
+ | 9.5941 | 5200 | - | 0.6872 |
868
+ | 9.7786 | 5300 | - | 0.6858 |
869
+ | 9.9631 | 5400 | - | 0.6861 |
870
+ | 10.0 | 5420 | - | 0.6863 |
871
+
872
+
873
+ ### Framework Versions
874
+ - Python: 3.12.6
875
+ - Sentence Transformers: 5.3.0
876
+ - Transformers: 5.5.1
877
+ - PyTorch: 2.11.0+cu130
878
+ - Accelerate: 1.13.0
879
+ - Datasets: 4.8.4
880
+ - Tokenizers: 0.22.2
881
+
882
+ ## Citation
883
+
884
+ ### BibTeX
885
+
886
+ #### Sentence Transformers
887
+ ```bibtex
888
+ @inproceedings{reimers-2019-sentence-bert,
889
+ title = "Sentence-BERT: Sentence Embeddings using Siamese BERT-Networks",
890
+ author = "Reimers, Nils and Gurevych, Iryna",
891
+ booktitle = "Proceedings of the 2019 Conference on Empirical Methods in Natural Language Processing",
892
+ month = "11",
893
+ year = "2019",
894
+ publisher = "Association for Computational Linguistics",
895
+ url = "https://arxiv.org/abs/1908.10084",
896
+ }
897
+ ```
898
+
899
+ #### MultipleNegativesRankingLoss
900
+ ```bibtex
901
+ @misc{oord2019representationlearningcontrastivepredictive,
902
+ title={Representation Learning with Contrastive Predictive Coding},
903
+ author={Aaron van den Oord and Yazhe Li and Oriol Vinyals},
904
+ year={2019},
905
+ eprint={1807.03748},
906
+ archivePrefix={arXiv},
907
+ primaryClass={cs.LG},
908
+ url={https://arxiv.org/abs/1807.03748},
909
+ }
910
+ ```
911
+
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+ <!--
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+ ## Glossary
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+
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+ *Clearly define terms in order to be accessible across audiences.*
916
+ -->
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+
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+ <!--
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+ ## Model Card Authors
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+
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+ *Lists the people who create the model card, providing recognition and accountability for the detailed work that goes into its construction.*
922
+ -->
923
+
924
+ <!--
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+ ## Model Card Contact
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+
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+ *Provides a way for people who have updates to the Model Card, suggestions, or questions, to contact the Model Card authors.*
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+ -->
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