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PMC4058084_f3_qa
"images/PMC4058084-f3.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a scientific figure." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 3. (A) Images of the labelled peroxisome...
PMC8326762_f5_d
"images/PMC8326762-f5.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"A Small Molecule Inhibitor of Pex3–Pex19 Interaction Disrupts Glycosome Biogenesis and Causes Lethality in Trypanosoma brucei\". Abstract: Trypanosomatid parasites, including Trypanosoma and Leishmania, are infectious zoonotic agents fo...
PMC3395097_f3
"images/PMC3395097-f3.png"
[ { "from": "human", "value": "<image>\nDescribe this scientific figure in detail." }, { "from": "gpt", "value": "Figure 3. Atg36 localises to peroxisomes and induces their autophagic degradation. (A) N- (left) and C- (right) GFP-tagged ATG36 under control of the GAL1 promoter was induced in atg36...
PMC8950469_f5_d
"images/PMC8950469-f5.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"Organelle Engineering in Yeast: Enhanced Production of Protopanaxadiol through Manipulation of Peroxisome Proliferation in Saccharomyces cerevisiae\". Abstract: Isoprenoids, which are natural compounds with diverse structures, possess s...
PMC12599240_multi
[ "images/PMC12599240-f1.png", "images/PMC12599240-f2.png" ]
[ { "from": "human", "value": "<image>\n<image>\nThese figures are from the study \"Move over endosymbionts, peroxisomes pass electrons too\". Summarise what they collectively show." }, { "from": "gpt", "value": "Figure 1: Figure 1. APX, ascorbate peroxidase; CAT, catalase; CPR, cytochrome p450 re...
PMC11103113_f4
"images/PMC11103113-f4.png"
[ { "from": "human", "value": "<image>\nDescribe this scientific figure in detail." }, { "from": "gpt", "value": "Figure 4. A new medial GFP fusion of PGD2 is active but does not localize in peroxisomes. (A) PGD2 monomer (PDB file obtained from Alphafold, and modifed by Protean 3D) with a large di...
PMC11087011_f2_d
"images/PMC11087011-f2.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"Peripheral peroxisomal β-oxidation engages neuronal serotonin signaling to drive stress-induced aversive memory in C. elegans\". Abstract: Physiological dysfunction confers negative valence to coincidental sensory cues to induce the for...
PMC4477233_f2_d
"images/PMC4477233-f2.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"Phosphorylation of Pex11p does not regulate peroxisomal fission in the yeast Hansenula polymorpha\". Abstract: Pex11p plays a crucial role in peroxisomal fission. Studies in Saccharomyces cerevisiae and Pichia pastoris indicated that Pe...
PMC6556978_multi
[ "images/PMC6556978-f1.png", "images/PMC6556978-f2.png", "images/PMC6556978-f3.png", "images/PMC6556978-f4.png", "images/PMC6556978-f5.png" ]
[ { "from": "human", "value": "<image>\n<image>\n<image>\n<image>\n<image>\nThese figures are from the study \"Characterization of the GPR1/FUN34/YaaH protein family in the green microalga Chlamydomonas suggests their role as intracellular membrane acetate channels\". Summarise what they collectively show." ...
PMC3400606_multi
[ "images/PMC3400606-f1.png", "images/PMC3400606-f2.png", "images/PMC3400606-f3.png", "images/PMC3400606-f4.png", "images/PMC3400606-f5.png" ]
[ { "from": "human", "value": "<image>\n<image>\n<image>\n<image>\n<image>\nThese figures are from the study \"Cre-Mediated Stress Affects Sirtuin Expression Levels, Peroxisome Biogenesis and Metabolism, Antioxidant and Proinflammatory Signaling Pathways\". Summarise what they collectively show." }, { ...
PMC6526838_f1_qa
"images/PMC6526838-f1.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a western blot / immunoblot." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 1. Four-step strategy for isolat...
PMC8717607_f6_d
"images/PMC8717607-f6.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"Metabolic Enzyme Alterations and Astrocyte Dysfunction in a Murine Model of Alexander Disease With Severe Reactive Gliosis\". Abstract: Alexander disease (AxD) is a rare and fatal neurodegenerative disorder caused by mutations in the ge...
PMC9919379_f1_qa
"images/PMC9919379-f1.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a schematic diagram." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 1. Diagrammatic representation of PA cat...
PMC3270307_f4
"images/PMC3270307-f4.png"
[ { "from": "human", "value": "<image>\nDescribe this scientific figure in detail." }, { "from": "gpt", "value": "Figure 4. pH optimum and substrate specificity of recombinant TbUGP. (A) The pH optimum of TbUGP was determined by comparing the yields of UDP-Glc using the HPLC assay. The error bars ...
PMC8431237_f2_d
"images/PMC8431237-f2.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"The Antihypertensive Drug Telmisartan Protects Oligodendrocytes from Cholesterol Accumulation and Promotes Differentiation by a PPAR-γ-Mediated Mechanism\". Abstract: Our previous studies have demonstrated that specific peroxisome proli...
PMC2173332_f7_qa
"images/PMC2173332-f7.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a western blot / immunoblot." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 7. Effects of multiple AOX knock...
PMC2657551_f4_d
"images/PMC2657551-f4.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"Enzyme activities and subcellular localization of members of the Arabidopsis glutathione transferase superfamily\". Abstract: Enzyme screens with Strep-tagged recombinant proteins and expression studies with the respective green fluores...
PMC8615043_f6_d
"images/PMC8615043-f6.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"Antioxidant Properties and Cytoprotective Effect of Pistacia lentiscus L. Seed Oil against 7β-Hydroxycholesterol-Induced Toxicity in C2C12 Myoblasts: Reduction in Oxidative Stress, Mitochondrial and Peroxisomal Dysfunctions and Attenuat...
PMC6137984_f5_d
"images/PMC6137984-f5.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"Conserved and differential transcriptional responses of peroxisome associated pathways to drought, dehydration and ABA\". Abstract: Peroxisome biogenesis, peroxisome β-oxidation and antioxidant enzymes show conserved upregulation in res...
PMC2990202_f5_d
"images/PMC2990202-f5.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"Arachidonic acid actions on functional integrity and attenuation of the negative effects of palmitic acid in a clonal pancreatic β-cell line\". Abstract: Chronic exposure of pancreatic β-cells to saturated non-esterified fatty acids can...
PMC11267555_f4_qa
"images/PMC11267555-f4.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a quantification / bar graph." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 4. Evaluation of the engineered...
PMC6063905_f5_d
"images/PMC6063905-f5.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"Seipin and the membrane-shaping protein Pex30 cooperate in organelle budding from the endoplasmic reticulum\". Abstract: Lipid droplets (LDs) and peroxisomes are ubiquitous organelles with central roles in eukaryotic cells. Although the...
PMC400753_f1_qa
"images/PMC400753-f1.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a scientific figure." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 1. Nucleotide sequences of the 5'-flanki...
PMC9753467_f4_d
"images/PMC9753467-f4.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"BNIP3L/NIX regulates both mitophagy and pexophagy\". Abstract: Mitochondria and peroxisomes are closely related metabolic organelles, both in terms of origin and in terms of function. Mitochondria and peroxisomes can also be turned over...
PMC10952002_f5_qa
"images/PMC10952002-f5.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a western blot / immunoblot." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 5. RNAi knockdown of TbPEX1 lead...
PMC2175187_f1_d
"images/PMC2175187-f1.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"Pex11p Plays a Primary Role in Medium-Chain Fatty Acid Oxidation, a Process That Affects Peroxisome Number and Size in Saccharomyces cerevisiae\". Abstract: The Saccharomyces cerevisiae peroxisomal membrane protein Pex11p has previously...
PMC11656475_f4
"images/PMC11656475-f4.png"
[ { "from": "human", "value": "<image>\nDescribe this scientific figure in detail." }, { "from": "gpt", "value": "Figure 4. Increased peroxisome numbers are likely associated with early stages of alcohol-induced liver injury, but are lost as fibrosis progresses. (A) Liver homogenates from three se...
PMC10469627_f4
"images/PMC10469627-f4.png"
[ { "from": "human", "value": "<image>\nDescribe this scientific figure in detail." }, { "from": "gpt", "value": "Figure 4. The N-terminal PEX19 binding site in PEX11 is conserved among species. (A) Multiple sequence alignment of N-terminal sequences of PEX11 proteins from parasites, baker’s yeast...
PMC6696164_f6_d
"images/PMC6696164-f6.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"Structural Mapping of Missense Mutations in the Pex1/Pex6 Complex\". Abstract: Peroxisome biogenesis disorders (PBDs) are nontreatable hereditary diseases with a broad range of severity. Approximately 65% of patients are affected by mut...
PMC8068806_f7_qa
"images/PMC8068806-f7.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a immunofluorescence micrograph." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 7. Immunofluorescent and imm...
PMC12786121_f5
"images/PMC12786121-f5.png"
[ { "from": "human", "value": "<image>\nDescribe this scientific figure in detail." }, { "from": "gpt", "value": "Figure 5. Lipid storage and metabolism are compromised in the hearts of the Pex11a knockout mice. (A,B): Electron micrographs of LDs (black arrowheads) and POs (black arrows) in LV car...
PMC9086359_f2_qa
"images/PMC9086359-f2.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a schematic diagram." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 2. PEX19C296S expression in PEX19 knock-...
PMC6751335_f1
"images/PMC6751335-f1.png"
[ { "from": "human", "value": "<image>\nDescribe this scientific figure in detail." }, { "from": "gpt", "value": "Figure 1. Characterization of MCs isolated from the striae of neonatal rats. Morphology of MCs on day 3 and 7 of culture (100x magnification). This picture shows the marginal cells, wh...
PMC12984136_f7_d
"images/PMC12984136-f7.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"Impaired Acetyl-CoA Compartmentalization Drives a Futile Lipogenic–Oxidative Cycle in N88S Seipinopathy\". Abstract: What are the main findings? The N88S seipin mutation disrupts acetyl-CoA compartmentalization, limiting its proper util...
PMC6417251_f2_qa
"images/PMC6417251-f2.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a quantification / bar graph." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 2. Inflammatory characteristics...
PMC4549881_f1
"images/PMC4549881-f1.png"
[ { "from": "human", "value": "<image>\nDescribe this scientific figure in detail." }, { "from": "gpt", "value": "Figure 1. a. Phosphatidyl ethanolamine 16:0/28:0 levels in Multiple Sclerosis. Cross sectional serum samples from each of the clinical groups were subjected to lipidomic analysis utili...
PMC10829319_f12_qa
"images/PMC10829319-f12.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a scientific figure." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 12. The correlation between somatic copy...
PMC9759912_f5_d
"images/PMC9759912-f5.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"Saturated very long-chain fatty acids regulate macrophage plasticity and invasiveness\". Abstract: Saturated very long-chain fatty acids (VLCFA, ≥ C22), enriched in brain myelin and innate immune cells, accumulate in X-linked adrenoleuk...
PMC3904162_f8
"images/PMC3904162-f8.png"
[ { "from": "human", "value": "<image>\nDescribe this scientific figure in detail." }, { "from": "gpt", "value": "Figure 8. TRKOs and their influence on transcription of other TR genes. Each TRKO mutant and goa1∆ is shown with arrows that connect common TR genes (rectangular boxes) affected in eac...
PMC6968987_f1_qa
"images/PMC6968987-f1.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a scientific figure." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 1. MRI examination at the age of 21 year...
PMC5210156_f1_qa
"images/PMC5210156-f1.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a western blot / immunoblot." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 1. Western blot detection of PEX...
PMC12042473_f6_qa
"images/PMC12042473-f6.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a scientific figure." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 6. The Nbr1 role involved in the pexopha...
PMC7477296_f1
"images/PMC7477296-f1.png"
[ { "from": "human", "value": "<image>\nDescribe this scientific figure in detail." }, { "from": "gpt", "value": "Figure 1. Knockdown of Pex3 in the Drosophila eye phenocopies the Rosy phenotype. (A) Wild type Drosophila eye pigment is a bright red-orange color. (B) Reduction of Pex3 activity spec...
PMC7001505_f1_d
"images/PMC7001505-f1.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"Peroxisomal fission is modulated by the mitochondrial Rho‐GTPases, Miro1 and Miro2\". Abstract: Peroxisomes are essential for a number of cellular functions, including reactive oxygen species metabolism, fatty acid β‐oxidation and lipid...
PMC3599312_f1_qa
"images/PMC3599312-f1.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a western blot / immunoblot." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 1. Pex14p protein levels and dis...
PMC6109679_f4_qa
"images/PMC6109679-f4.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a scientific figure." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 4. Melatonin effect on cell growth viabi...
PMC12796351_f10
"images/PMC12796351-f10.png"
[ { "from": "human", "value": "<image>\nDescribe this scientific figure in detail." }, { "from": "gpt", "value": "Figure 10. Multicolor STED nanoscopy reveals that in neuronal cells, MDSs comprise structurally and functionally distinct populations that mediate quality control, transport stress-rel...
PMC2175277_f2
"images/PMC2175277-f2.png"
[ { "from": "human", "value": "<image>\nDescribe this scientific figure in detail." }, { "from": "gpt", "value": "Figure 2. Effects of anti–Pex1p Fab and anti–Pex6p Fab on peroxisome priming, docking, and fusion. P1 from wild-type cells and P2 from pex5KO cells containing the precursor form of the...
PMC4589490_f5_qa
"images/PMC4589490-f5.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a western blot / immunoblot." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 5. (a) HEK293 cells expressing M...
PMC8688145_f9_qa
"images/PMC8688145-f9.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a quantification / bar graph." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 9. (a-b) Pex2 transcript in the...
PMC9838548_f5_d
"images/PMC9838548-f5.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"Peroxisomal KAT2 (3-ketoacyl-CoA thiolase 2) gene has a key role in gingerol biosynthesis in ginger (Zingiber officinale Rosc.)\". Abstract: Ginger is an important spice crop with medicinal values and gingerols are the most abundant pun...
PMC6721249_f4
"images/PMC6721249-f4.png"
[ { "from": "human", "value": "<image>\nDescribe this scientific figure in detail." }, { "from": "gpt", "value": "Figure 4. Peroxisomes in an antiviral response. (A) Peroxisomes are signaling hubs for the induction of a Type III interferon response by harboring the antiviral signaling protein MAVS...
PMC4978895_f6_qa
"images/PMC4978895-f6.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a immunofluorescence micrograph." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 6. Supersized LD phenotype o...
PMC3668122_f5_qa
"images/PMC3668122-f5.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a scientific figure." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 5. Catalase (a) and peroxidase (b) activ...
PMC5762779_f7
"images/PMC5762779-f7.png"
[ { "from": "human", "value": "<image>\nDescribe this scientific figure in detail." }, { "from": "gpt", "value": "Figure 7. Pex15 bridges Pex5/Pex14 with Pex1/Pex6. a A pull-down binding assay of GST-Pex14 with Pex5, Pex15 1-327-FLAG, and Pex1/Pex6 in the presence of ATP shows that Pex1/Pex6 assoc...
PMC11895971_f2_qa
"images/PMC11895971-f2.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a scientific figure." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 2. circSEC61A1 regulates the malignant p...
PMC10231715_f3_d
"images/PMC10231715-f3.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"Uncombable Hair in a Case of Zellweger Syndrome – A New Association\". Abstract: Zellweger syndrome (ZS) is a rare autosomal recessive, peroxisomal biogenesis disorder (PBD) that occurs due to a mutation in any of the thirteen peroxin (...
PMC8112170_multi
[ "images/PMC8112170-f1.png", "images/PMC8112170-f2.png", "images/PMC8112170-f3.png", "images/PMC8112170-f4.png", "images/PMC8112170-f5.png" ]
[ { "from": "human", "value": "<image>\n<image>\n<image>\n<image>\n<image>\nThese figures are from the study \"The Peroxisomal Localization of Hsd17b4 Is Regulated by Its Interaction with Phosphatidylserine\". Summarise what they collectively show." }, { "from": "gpt", "value": "Figure 1: Figure 1...
PMC3676407_f3
"images/PMC3676407-f3.png"
[ { "from": "human", "value": "<image>\nDescribe this scientific figure in detail." }, { "from": "gpt", "value": "Figure 3. A) pHluorin calibration curves: Cells expressing compartment targeted-pHluorin were pregrown in SCURA (48 h; 30°C; 600 rpm), inoculated in SCURA (A600 = 0.001) and grown (25°...
PMC404372_f4_qa
"images/PMC404372-f4.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a quantification / bar graph." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 4. Mouse peroxisomal 3-ketoacyl...
PMC8615211_f5_qa
"images/PMC8615211-f5.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a scientific figure." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 5. Phenotype of siliques from Arabidopsi...
PMC11421175_f4_qa
"images/PMC11421175-f4.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a scientific figure." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 4. T2-weighted and FLAIR images of patie...
PMC9086853_f8_qa
"images/PMC9086853-f8.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a schematic diagram." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 8. The pool and sulfenylation profiles o...
PMC9758912_f4_qa
"images/PMC9758912-f4.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a scientific figure." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 4. Dynamical regulation of fatty alcohol...
PMC9919379_f1_d
"images/PMC9919379-f1.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"Plant Peroxisomal Polyamine Oxidase: A Ubiquitous Enzyme Involved in Abiotic Stress Tolerance\". Abstract: Polyamines (PAs) are positively charged amines that are present in all organisms. In addition to their functions specific to grow...
PMC12602707_multi_2
[ "images/PMC12602707-f6.png", "images/PMC12602707-f7.png", "images/PMC12602707-f8.png" ]
[ { "from": "human", "value": "<image>\n<image>\n<image>\nThese figures are from the study \"Alterations in peroxisome-mitochondria interplay in skeletal muscle accelerate muscle dysfunction\". Summarise what they collectively show." }, { "from": "gpt", "value": "Figure 6: Figure 6. A Left: repres...
PMC5645307_f1
"images/PMC5645307-f1.png"
[ { "from": "human", "value": "<image>\nDescribe this scientific figure in detail." }, { "from": "gpt", "value": "Figure 1. Pparα Agonists Induce miR-181a2 Expression (A and B) HepG2 cells were treated with WY-14643 (200 μM) or vehicle DMSO for 24 hr, and then the expression of Cpt1a (A) and Lc3a ...
PMC4517885_f1_d
"images/PMC4517885-f1.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"One of Three Pex11 Family Members Is Required for Peroxisomal Proliferation and Full Virulence of the Rice Blast Fungus Magnaporthe oryzae\". Abstract: Peroxisomes play important roles in metabolisms of eukaryotes and infection of plant...
PMC3783979_f1_d
"images/PMC3783979-f1.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"Emerging roles of mitochondria in the evolution, biogenesis, and function of peroxisomes\". Abstract: In the last century peroxisomes were thought to have an endosymbiotic origin. Along with mitochondria and chloroplasts, peroxisomes pr...
PMC5210156_f3
"images/PMC5210156-f3.png"
[ { "from": "human", "value": "<image>\nDescribe this scientific figure in detail." }, { "from": "gpt", "value": "Figure 3. Western blot detection of PEX13 in HeLa/Parkin cells transfected with indicated siRNA and siRNA‐resistant PEX13 plasmid. To achieve similar PEX13 protein expression levels, 0...
PMC9538651_f3_qa
"images/PMC9538651-f3.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a scientific figure." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 3. Electron microscopy imaging of the pa...
PMC9944197_f2_qa
"images/PMC9944197-f2.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a quantification / bar graph." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 2. (A) Representative images of...
PMC2883949_f2_d
"images/PMC2883949-f2.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"Peroxisomal Membrane Proteins Insert into the Endoplasmic Reticulum\". Abstract: We demonstrate that the entry of peroxisomal membrane proteins (PMPs) into the ER is mediated by the general ER import machinery. Within the ER, PMPs attai...
PMC9456058_multi
[ "images/PMC9456058-f1.png", "images/PMC9456058-f2.png" ]
[ { "from": "human", "value": "<image>\n<image>\nThese figures are from the study \"Genetics behind Cerebral Disease with Ocular Comorbidity: Finding Parallels between the Brain and Eye Molecular Pathology\". Summarise what they collectively show." }, { "from": "gpt", "value": "Figure 1: Figure 1....
PMC5752207_f3_qa
"images/PMC5752207-f3.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a western blot / immunoblot." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 3. (a) Cross-sections of Lrp1 co...
PMC5612355_f1
"images/PMC5612355-f1.png"
[ { "from": "human", "value": "<image>\nDescribe this scientific figure in detail." }, { "from": "gpt", "value": "Figure 1. Development of luciferase assay to monitor autophagy in real time. (A) Reporter strain constructed when grown in presence of fatty acid containing media, results in peroxisom...
PMC4046565_f2_qa
"images/PMC4046565-f2.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a immunofluorescence micrograph." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 2. (A) Schematic depicting t...
PMC6678304_f1_qa
"images/PMC6678304-f1.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a scientific figure." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 1. Graphic representation of the porto-s...
PMC10515436_f1
"images/PMC10515436-f1.png"
[ { "from": "human", "value": "<image>\nDescribe this scientific figure in detail." }, { "from": "gpt", "value": "Figure 1. Mtb infection triggers peroxisome biogenesis in human macrophages. (A) Heatmap of differentially expressed genes from RNA sequencing analysis of iPSDM infected with either Mt...
PMC12154719_f6
"images/PMC12154719-f6.png"
[ { "from": "human", "value": "<image>\nDescribe this scientific figure in detail." }, { "from": "gpt", "value": "Figure 6. Substrate (phytanoyl-CoA) binds to inward-open state of ABCD3 and brings NBDs closer together. ATP binding brings NBDs further together resulting in an outward-open state (PD...
PMC7688997_f8
"images/PMC7688997-f8.png"
[ { "from": "human", "value": "<image>\nDescribe this scientific figure in detail." }, { "from": "gpt", "value": "Figure 8. Overexpression of SUPA leads to broad transcriptomic changes. (A) Venn diagram showing the overlap of DEGs between two SUPA-overexpression lines. 388 DEGs were presented in b...
PMC2156211_f3_d
"images/PMC2156211-f3.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"Fusion of Small Peroxisomal Vesicles in Vitro Reconstructs an Early Step in the in Vivo Multistep Peroxisome Assembly Pathway of Yarrowia lipolytica\". Abstract: We have identified and purified six subforms of peroxisomes, designated P1...
PMC12352285_f3_qa
"images/PMC12352285-f3.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a schematic diagram." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 3. Human UAS cDNA PEX2 and PEX16 referen...
PMC4052807_f3_d
"images/PMC4052807-f3.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"High-Confidence Glycosome Proteome for Procyclic Form Trypanosoma brucei by Epitope-Tag Organelle Enrichment and SILAC Proteomics\". Abstract: The glycosome of the pathogenic African trypanosome Trypanosoma brucei is a specialized perox...
PMC9898756_f5_qa
"images/PMC9898756-f5.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a scientific figure." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 5. Peroxisomal β-oxidation of fatty acid...
PMC10470208_multi
[ "images/PMC10470208-f1.png", "images/PMC10470208-f2.png", "images/PMC10470208-f3.png", "images/PMC10470208-f4.png" ]
[ { "from": "human", "value": "<image>\n<image>\n<image>\n<image>\nThese figures are from the study \"Identification of bile acid-CoA:amino acid N-acyltransferase as the hepatic N-acyl taurine synthase for polyunsaturated fatty acids\". Summarise what they collectively show." }, { "from": "gpt", "...
PMC7498260_f1_2_qa
"images/PMC7498260-f1-2.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a western blot / immunoblot." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 1. (A) Fao cells (4 × 106 cells ...
PMC11661142_multi
[ "images/PMC11661142-f1.png", "images/PMC11661142-f2.png", "images/PMC11661142-f3.png", "images/PMC11661142-f4.png", "images/PMC11661142-f5.png" ]
[ { "from": "human", "value": "<image>\n<image>\n<image>\n<image>\n<image>\nThese figures are from the study \"PEX1G843D remains functional in peroxisome biogenesis but is rapidly degraded by the proteasome\". Summarise what they collectively show." }, { "from": "gpt", "value": "Figure 1: Figure 1...
PMC6989686_f1_qa
"images/PMC6989686-f1.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a western blot / immunoblot." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 1. a Representative CARS live im...
PMC11627416_f9_qa
"images/PMC11627416-f9.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a immunofluorescence micrograph." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 9. (A-L): Immunofluorescence...
PMC9244630_f4_d
"images/PMC9244630-f4.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"Inferred Subcellular Localization of Peroxisomal Matrix Proteins of Guillardia theta Suggests an Important Role of Peroxisomes in Cryptophytes\". Abstract: Peroxisomes participate in several important metabolic processes in eukaryotic c...
PMC7477296_f1_d
"images/PMC7477296-f1.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"Rosy Beginnings: Studying Peroxisomes in Drosophila\". Abstract: Research using the fruit fly Drosophila melanogaster has traditionally focused on understanding how mutations affecting gene regulation or function affect processes linked...
PMC10834178_f1
"images/PMC10834178-f1.png"
[ { "from": "human", "value": "<image>\nDescribe this scientific figure in detail." }, { "from": "gpt", "value": "Figure 1. EHHADH expression is downregulated in renal cancer, and low EHHADH expression correlates with reduced survival. (A) EHHADH mRNA expression of primary ccRCC tumor samples comp...
PMC6136741_f3_qa
"images/PMC6136741-f3.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a quantification / bar graph." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 3. Staining of mouse lung tissu...
PMC11253437_f1_qa
"images/PMC11253437-f1.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a scientific figure." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 1. Average in-patient and out-patient co...
PMC8156035_f1_d
"images/PMC8156035-f1.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"Modulation of Photorespiratory Enzymes by Oxidative and Photo-Oxidative Stress Induced by Menadione in Leaves of Pea (Pisum sativum)\". Abstract: Photorespiration, an essential component of plant metabolism, is concerted across four sub...
PMC10647558_f1_d
"images/PMC10647558-f1.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"Genetic and Lifestyle-Related Factors Influencing Serum Hyper-Propionylcarnitine Concentrations and Their Association with Metabolic Syndrome and Cardiovascular Disease Risk\". Abstract: The genetic and environmental determinants of ser...
PMC11124372_f2_d
"images/PMC11124372-f2.png"
[ { "from": "human", "value": "<image>\nThis figure is from the article \"Enzymatic Metabolic Switches of Astrocyte Response to Lipotoxicity as Potential Therapeutic Targets for Nervous System Diseases\". Abstract: Astrocytes play a pivotal role in maintaining brain homeostasis. Recent research has highlighte...
PMC7463047_f3_qa
"images/PMC7463047-f3.png"
[ { "from": "human", "value": "<image>\nWhat type of scientific figure is this?" }, { "from": "gpt", "value": "This is a scientific figure." }, { "from": "human", "value": "Describe it in detail." }, { "from": "gpt", "value": "Figure 3. Pre‐ and post‐dietary intervention 30...
PMC11262808_f7
"images/PMC11262808-f7.png"
[ { "from": "human", "value": "<image>\nDescribe this scientific figure in detail." }, { "from": "gpt", "value": "Figure 7. Structural analysis of CRAT variants (PDB 1S5O). The candidate pathogenic variant we identified (p.T305M) is in red (sticks), variants from cBioPortal are in green (sticks)—o...