MaziyarPanahi (Maziyar Panahi)

reacted to fffiloni's post with 🚀🔥 1 day ago

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1330

A few weeks ago, @victor opened the door: coding agents can now ship Hugging Face Spaces autonomously.

I pulled on that thread.

As someone who builds and ships Gradio demos regularly, I didn’t just want to reproduce the loop. I wanted to see what happens when that loop is plugged into the whole Hugging Face stack.

The interesting part is not only that an agent can ship a Space.

It’s what happens when Space generation becomes a first-class Hugging Face workflow.

That became Agentic Space Factory.

More soon. 🤗

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posted an update 3 months ago

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Training mRNA Language Models Across 25 Species for $165

We built an end-to-end protein AI pipeline covering structure prediction, sequence design, and codon optimization. After comparing multiple transformer architectures for codon-level language modeling, CodonRoBERTa-large-v2 emerged as the clear winner with a perplexity of 4.10 and a Spearman CAI correlation of 0.40, significantly outperforming ModernBERT. We then scaled to 25 species, trained 4 production models in 55 GPU-hours, and built a species-conditioned system that no other open-source project offers. Complete results, architectural decisions, and runnable code below.

https://huggingface.co/blog/OpenMed/training-mrna-models-25-species

posted an update 3 months ago

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We annotated 119K medical images with two frontier VLMs (Qwen 3.5, Kimi K2.5), cross-validated at 93% agreement, and produced 110K training records, all for under $500. Fine-tuning 3 small models (2-3B params) improved all benchmarks: best model reaches +15.0% average exact match.

Everything is open-sourced: datasets, adapters, and code.

https://huggingface.co/blog/OpenMed/synthvision

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replied to their post 4 months ago

thank you! hope you enjoyed and stay tuned for Part II! 🙏

posted an update 4 months ago

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DNA, mRNA, proteins, AI. I spent the last year going deep into computational biology as an ML engineer. This is Part I of what I found. 🧬

In 2024, AlphaFold won the Nobel Prize in Chemistry.

By 2026, the open-source community had built alternatives that outperform it.

That's the story I find most interesting about protein AI right now. Not just the science (which is incredible), but the speed at which open-source caught up. Multiple teams, independently, reproduced and then exceeded AlphaFold 3's accuracy with permissive licenses. The field went from prediction to generation: we're not just modeling known proteins anymore, we're designing new ones.

I spent months mapping this landscape for ML engineers. What the architectures actually are (spoiler: transformers and diffusion models), which tools to use for what, and which ones you can actually ship commercially.

New post on the Hugging Face blog: https://huggingface.co/blog/MaziyarPanahi/protein-ai-landscape

Hope you all enjoy! 🤗

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replied to their post 5 months ago

Follow OpenMed for more releases! 🔥

posted an update 5 months ago

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Announcing: OpenMed Multilingual PII Detection Models

Today I am releasing 105 open-source models for Personally Identifiable Information (PII) detection in French, German, and Italian.

All Apache 2.0 licensed. Free for commercial use. No restrictions.

Performance:

- French: 97.97% F1 (top model)
- German: 97.61% F1 (top model)
- Italian: 97.28% F1 (top model)

All top-10 models per language exceed 96% F1

Coverage:

55+ PII entity types per language
Native ID formats: NSS (French), Sozialversicherungsnummer (German), Codice Fiscale (Italian)
Language-specific address, phone, and name patterns

Training Data:

French: 49,580 samples
German: 42,250 samples
Italian: 40,944 samples

Why Multilingual?

European healthcare operates in European languages. Clinical notes, patient records, and medical documents are generated in French, German, Italian, and other languages.

Effective de-identification requires:

- Native language understanding — not translation
- Local ID format recognition — each country has unique patterns
- Cultural context awareness — names, addresses, and formats vary
- These models deliver production-ready accuracy without requiring data to leave your infrastructure or language.

HIPAA & GDPR Compliance
Built for US and European privacy regulations:

- On-premise deployment: Process data locally with zero external dependencies
- Data sovereignty: No API calls, no cloud services, no cross-border transfers
- Air-gapped capable: Deploy in fully isolated environments if required
- Regulatory-grade accuracy: Supporting Expert Determination standards
- HIPAA and GDPR compliance across languages, without compliance gaps.

Use Cases
- Hospital EHR systems: Automated patient record de-identification
- Clinical research: Multilingual dataset preparation for studies
- Insurance companies: Claims processing across

https://huggingface.co/collections/OpenMed/multilingual-pii-and-de-identification

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posted an update 5 months ago

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From Golden Gate Bridge to Broken JSON: Why Anthropic's SAE Steering Fails for Structured Output

I ran 6 experiments trying to use Anthropic's SAE steering for JSON generation.

- Base model: 86.8% valid JSON
- Steering only: 24.4%
- Fine-tuned: 96.6%
- FSM constrained: 100%

Steering is for semantics, not syntax.

https://huggingface.co/blog/MaziyarPanahi/sae-steering-json

replied to their post 5 months ago

you are welcome! please follow OpenMed for future release! 🤗

replied to ZennyKenny's post 5 months ago

i once announced i crossed 4k on X, celebrated it with the community. just to come back in 3 days and see it down to 3600! 😅 i mean, bots are bad and don't make the platform look good so they should be removed. but took me a long time to go back to 4k! 😊

replied to their post 5 months ago

Please follow OpenMed 🤗

posted an update 5 months ago

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🚨 Day 8/8: OpenMed Medical Reasoning Dataset Release - THE GRAND FINALE

Today I complete my 8-day release series with Medical-Reasoning-SFT-Mega.
The largest open medical reasoning dataset, combining 7 state-of-the-art AI models with fair distribution deduplication.

THE 7 SOURCE MODELS (Original Sample Counts):

1. Trinity-Mini: 810,284 samples
2. Qwen3-Next-80B: 604,249 samples
3. GPT-OSS-120B: 506,150 samples
4. Nemotron-Nano-30B: 444,544 samples
5. GLM-4.5-Air: 225,179 samples
6. MiniMax-M2.1: 204,773 samples
7. Baichuan-M3-235B: 124,520 samples

TOTAL BEFORE DEDUPLICATION: 2,919,699 samples

TOKEN COUNTS:
- Content tokens: 2.22 Billion
- Reasoning tokens: 1.56 Billion
- Total tokens: 3.78 Billion
- Samples with chain-of-thought: 100%

Quick Start:

from datasets import load_dataset
ds = load_dataset("OpenMed/Medical-Reasoning-SFT-Mega")

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reacted to danielhanchen's post with 🚀😎 5 months ago

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3555

You can now run Kimi K2.5 locally! 🔥

We shrank the 1T model to 240GB (-60%) via Dynamic 1-bit.
Get >40 tok/s on 242GB or 622GB VRAM/RAM for near full precision.

GGUF: unsloth/Kimi-K2.5-GGUF

Guide: https://unsloth.ai/docs/models/kimi-k2.5

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reacted to their post with 🚀❤️ 6 months ago

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🎉 OpenMed 2025 Year in Review: 6 Months of Open Medical AI

I'm thrilled to share what the OpenMed community has accomplished since our July 2025 launch!

📊 The Numbers

29,700,000 downloads Thank you! 🙏

- 481 total models (475 medical NER models + 6 fine-tuned LLMs)
- 475 medical NER models in [OpenMed](

OpenMed ) organization
- 6 fine-tuned LLMs in [openmed-community](

openmed-community )
- 551,800 PyPI downloads of the [openmed package](https://pypi.org/project/openmed/)
- 707 followers on HuggingFace (you!)
- 97 GitHub stars on the [toolkit repo](https://github.com/maziyarpanahi/openmed)

🏆 Top Models by Downloads

1. [OpenMed-NER-PharmaDetect-SuperClinical-434M]( OpenMed/OpenMed-NER-PharmaDetect-SuperClinical-434M) — 147,305 downloads
2. [OpenMed-NER-ChemicalDetect-ElectraMed-33M]( OpenMed/OpenMed-NER-ChemicalDetect-ElectraMed-33M) — 126,785 downloads
3. [OpenMed-NER-BloodCancerDetect-TinyMed-65M]( OpenMed/OpenMed-NER-BloodCancerDetect-TinyMed-65M) — 126,465 downloads

🔬 Model Categories

Our 481 models cover comprehensive medical domains:

- Disease Detection (~50 variants)
- Pharmaceutical Detection (~50 variants)
- Oncology Detection (~50 variants)
- Genomics/DNA Detection (~80 variants)
- Chemical Detection (~50 variants)
- Species/Organism Detection (~60 variants)
- Protein Detection (~50 variants)
- Pathology Detection (~50 variants)
- Blood Cancer Detection (~30 variants)
- Anatomy Detection (~40 variants)
- Zero-Shot NER (GLiNER-based)

OpenMed
OpenMed NER: Open-Source, Domain-Adapted State-of-the-Art Transformers for Biomedical NER Across 12 Public Datasets (2508.01630)
https://huggingface.co/collections/OpenMed/medical-and-clinical-ner
https://huggingface.co/collections/OpenMed/zeroshot-medical-and-clinical-ner
OpenMed/Medical-Reasoning-SFT-GPT-OSS-120B

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replied to their post 6 months ago

Full article: OpenMed: Six Months of Open-Source Medical AI and the Road Ahead

posted an update 6 months ago

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🎉 OpenMed 2025 Year in Review: 6 Months of Open Medical AI

I'm thrilled to share what the OpenMed community has accomplished since our July 2025 launch!

📊 The Numbers

29,700,000 downloads Thank you! 🙏

- 481 total models (475 medical NER models + 6 fine-tuned LLMs)
- 475 medical NER models in [OpenMed](

OpenMed ) organization
- 6 fine-tuned LLMs in [openmed-community](

openmed-community )
- 551,800 PyPI downloads of the [openmed package](https://pypi.org/project/openmed/)
- 707 followers on HuggingFace (you!)
- 97 GitHub stars on the [toolkit repo](https://github.com/maziyarpanahi/openmed)

🏆 Top Models by Downloads

1. [OpenMed-NER-PharmaDetect-SuperClinical-434M]( OpenMed/OpenMed-NER-PharmaDetect-SuperClinical-434M) — 147,305 downloads
2. [OpenMed-NER-ChemicalDetect-ElectraMed-33M]( OpenMed/OpenMed-NER-ChemicalDetect-ElectraMed-33M) — 126,785 downloads
3. [OpenMed-NER-BloodCancerDetect-TinyMed-65M]( OpenMed/OpenMed-NER-BloodCancerDetect-TinyMed-65M) — 126,465 downloads

🔬 Model Categories

Our 481 models cover comprehensive medical domains:

- Disease Detection (~50 variants)
- Pharmaceutical Detection (~50 variants)
- Oncology Detection (~50 variants)
- Genomics/DNA Detection (~80 variants)
- Chemical Detection (~50 variants)
- Species/Organism Detection (~60 variants)
- Protein Detection (~50 variants)
- Pathology Detection (~50 variants)
- Blood Cancer Detection (~30 variants)
- Anatomy Detection (~40 variants)
- Zero-Shot NER (GLiNER-based)

OpenMed
OpenMed NER: Open-Source, Domain-Adapted State-of-the-Art Transformers for Biomedical NER Across 12 Public Datasets (2508.01630)
https://huggingface.co/collections/OpenMed/medical-and-clinical-ner
https://huggingface.co/collections/OpenMed/zeroshot-medical-and-clinical-ner
OpenMed/Medical-Reasoning-SFT-GPT-OSS-120B

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reacted to Kseniase's post with 🔥 10 months ago

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7128

10 Latest Preference Optimization Techniques

Models need feedback on what makes outputs “good” or “bad.” Policy optimization (PO) turns preferences and rewards into actual training signals. This field is evolving quickly, moving far beyond classics like PPO and GRPO. So here is our overview of 10 newest PO methods:

1. Pref-GRPO → Pref-GRPO: Pairwise Preference Reward-based GRPO for Stable Text-to-Image Reinforcement Learning (2508.20751)
Stabilizes text-to-image reinforcement learning (RL) with pairwise preference rewards and a unified UNIGENBENCH benchmark

2. PVPO (Policy with Value Preference Optimization) → PVPO: Pre-Estimated Value-Based Policy Optimization for Agentic Reasoning (2508.21104)
This critic-free RL method uses a pre-trained model as a reference anchor to reduce bias and guide learning, selecting high-value examples through data pre-sampling

3. DCPO (Dynamic Clipping Policy Optimization) → DCPO: Dynamic Clipping Policy Optimization (2509.02333)
Uses dynamic clipping, which adjusts probability limits per token for better token exploration, and smooth reward standardization to balance rewards over training steps and prevent wasted updates

4. ARPO (Agentic Reinforced Policy Optimization) → Agentic Reinforced Policy Optimization (2507.19849)
Optimizes multi-turn LLM agents that use external tools. It uses an entropy-based adaptive rollout to explore post-tool use and an advantage attribution method to better assign credit across steps, leading to more efficient tool use with fewer resources

5. GRPO-RoC (Group Relative Policy Optimization with Resampling-on-Correct) → rStar2-Agent: Agentic Reasoning Technical Report (2508.20722)
Oversamples rollouts, then resamples them to keep diverse mistakes and only the highest-quality correct answers. It reduces noises and ends up with stronger reasoning in a code environment

Read further below ⬇️
If you like this, also subscribe to the Turing post: https://www.turingpost.com/subscribe

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